Patents by Inventor Jacques De Bakker Milo Thomas

Jacques De Bakker Milo Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Means and Methods for Influencing Electrical Activity of Cells
    Publication number: 20110077702
    Abstract: The invention provides means and methods for providing a cell with a spontaneous electrical activity and means and methods for increasing the depolarization rate of a cell having a spontaneous electrical activity. Means and methods are provided comprising: providing a cell with a compound capable of providing and/or increasing a pacemaker current If, and diminishing electrical coupling between said cell and surrounding cells and/or reducing the inward rectifier current IK1 of said cell, and or increasing the availability of INa at depolarized potentials, preferably using overexpression of additional sodium channels.
    Type: Application
    Filed: September 27, 2010
    Publication date: March 31, 2011
    Applicant: Academisch Medisch Centrum Bij de Universiteit van Amsterdam
    Inventors: Gerard J.J. Boink, Hanno L. Tan, Jacques De Bakker Milo Thomas