Patents by Inventor Jacques Demassey

Jacques Demassey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6838453
    Abstract: The invention concerns vitronectin receptor antagonist compounds of formula (3): R1—Y—A—B—D—E—F—G wherein R1, Y, A, B, D, E, F, and G are as defined in the description, their physiologically acceptable salts and their prodrugs, methods for preparing compounds of formula (I), their use, in particular as medicine and pharmaceutical compositions containing them.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: January 4, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Jacques Demassey, Jean-Francois Gourvest, Jean-Marie Ruxer, John Bernard Weston, Jean-Michel LeFrancois
  • Publication number: 20040225111
    Abstract: The invention concerns vitronectin receptor antagonist compounds of formula (I): R1—Y-A-B-D-E-F-G wherein R1, Y, A, B, D, E, F, and G are as defined in the description, their physiologically acceptable salts and their prodrugs, methods for preparing compounds of formula (I), their use, in particular as medicine and pharmaceutical compositions containing them.
    Type: Application
    Filed: November 4, 2002
    Publication date: November 11, 2004
    Inventors: Jacques Demassey, Jean-Francois Gourvest, Jean-Marie Ruxer, John Bernard Weston, Jean-Michel LeFrancois
  • Publication number: 20030225302
    Abstract: Aromatic amides, their preparation process and their use as pesticides 1
    Type: Application
    Filed: May 2, 2003
    Publication date: December 4, 2003
    Inventors: Jacques Demassey, Robert Peek, Antonio Ugolini, John Weston
  • Patent number: 6579902
    Abstract: Compounds of formula (I); wherein R1=alkyl, alkenyl or alkynyl, O-alkyl, O-alkenyl or optionally substituted, optionally interrupted O-alkynyl; R2=hydrogen or halogen; R3=hydrogen, alkyl or halogen; R4=NHR′ or NHOR″, R′ or R″ are identical or different and represent hydrogen, alkyl, alkenyl or alkynyl, aryl; R5=hydrogen or O-alkyl; R6=alkyl or CH2—O-alkyl; R7=hydrogen or alkyl or R6 et R7 form a cycle together with the carbon carrying them in addition to the addition salts thereof with bases. The compounds of formula (I) have antibiotic properties.
    Type: Grant
    Filed: January 9, 2002
    Date of Patent: June 17, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Jacques Demassey, Michel Klich, Branislav Musicki
  • Patent number: 6555709
    Abstract: Aromatic amides, their preparation process and their use as pesticides.
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: April 29, 2003
    Assignee: Hoechst Schering AgrEvo S.A.
    Inventors: Agnés Brouillard, Jacques Demassey, Philippe Dutheil, John Weston
  • Publication number: 20030008913
    Abstract: Compounds of formula (I) in which R represents the remainder of an alcohol used in the pyrethroid series, in all their possible stereoisomer forms as well as their mixtures, and compositions comprising them. The compounds of formula (I) are useful as pesticides.
    Type: Application
    Filed: May 7, 2002
    Publication date: January 9, 2003
    Inventors: Andrew Adams, Jean Pierre Demoute, Jacques Demassey, Didier Babin
  • Publication number: 20020068838
    Abstract: Compounds of formula (I) in which a, b, c, 1
    Type: Application
    Filed: December 28, 1999
    Publication date: June 6, 2002
    Inventors: JACQUES DEMASSEY, ROBERT PEEK, ANTONIO UGOLINI, JOHN WESTON
  • Patent number: 6159973
    Abstract: The subject of the invention is the compounds of formula (I):Q(CH.sub.2).sub.a --(X.sub.1).sub.b --Q.sub.1 --Q.sub.2 --C(X.sub.2)--N(R.sub.1)(R.sub.2) (I)in which:Q represents an aryl radical,X.sub.1 represents oxy, thio, sulphinyl or sulphonyl,X.sub.2 represents oxygen or sulphur,Q.sub.1 represents a cyclopropanediyl radical,Q.sub.2 represents an arylene radical,R.sub.1 and R.sub.2 represent:either a hydrogen atom or a hydrocarbon radicalor one of the groupsR.sub.3 --C.dbd.X.sub.3, (R.sub.3).sub.2 --P.dbd.X.sub.3, T.sub.2 --R.sub.5 or S(O).sub.j --N(R.sub.6)(R.sub.7)in which X.sub.3 represents an oxygen atom or a sulphur atom, T.sub.2 represents a bivalent oxy, carbonyl or oxycarbonyl group and j is equal to 0, 1 or 2,their preparation process and their use as pesticides.
    Type: Grant
    Filed: July 21, 1999
    Date of Patent: December 12, 2000
    Assignee: Hoechst Schering Agrevo S.A.
    Inventors: Jacques Demassey, Michel Gohar, Christian Wehrey
  • Patent number: 6013837
    Abstract: The subject of the invention is the compounds of formula (I):Q(CH.sub.2)a-(X.sub.1).sub.b -Q.sub.1 -Q.sub.2 -C(X.sub.2)--N(R.sub.1)(R.sub.2) (I)in which:Q represents an aryl radical,X.sub.1 represents oxy, thio, sulphinyl or sulphonyl,X.sub.2 represents oxygen or sulphur,Q.sub.1 represents a cyclopropanediyl radical,Q.sub.2 represents an arylene radical,R.sub.1 and R.sub.2 represent:either a hydrogen atom or a hydrocarbon radical or one of the groupsR.sub.3 --C.dbd.X.sub.3, (R.sub.3).sub.2 --P.dbd.X.sub.3, T.sub.2 -R.sub.5 or S(O).sub.j --N(R.sub.6)(R.sub.7)in which X.sub.3 represents an oxygen atom or a sulphur atom, T.sub.2 represents a bivalent oxy, carbonyl or oxycarbonyl group and j is equal to 0, 1 or 2, their preparation process and their use as pesticides.
    Type: Grant
    Filed: July 30, 1997
    Date of Patent: January 11, 2000
    Assignee: Hoechst Marion Roussel
    Inventors: Jacques Demassey, Michel Gohar, Christian Wehrey
  • Patent number: 5972839
    Abstract: The invention relates to novel .alpha.-fluoroacrylic acid derivatives, to active compound/antidote combinations which comprise .alpha.-fluoroacrylic acid derivatives and are outstandingly suitable for use in crops of useful plants, to their use and to methods for protecting crop plants.
    Type: Grant
    Filed: December 17, 1997
    Date of Patent: October 26, 1999
    Assignee: Hoechst Schering AgrEvo GmbH
    Inventors: Frank Ziemer, Lothar Willms, Klaus Bauer, Hermann Bieringer, Christopher Rosinger, Jacques Demassey
  • Patent number: 5405865
    Abstract: A compound in all possible stereoisomeric forms and mixtures thereof of the formula ##STR1## wherein the substituents are defined as in the specification having pesticidal properties.
    Type: Grant
    Filed: February 3, 1993
    Date of Patent: April 11, 1995
    Assignee: Roussel-Uclaf
    Inventors: Marc Benoit, Jacques Demassey, Jean-Pierre Demoute
  • Patent number: 5401771
    Abstract: An insecticidal composition comprising an insecticidally effective amount of (S) .alpha.-cyano-3-phenoxy-benzyl(1R, trans) 2,2-dimethyl-3-[(.DELTA.Z) 2-fluoro-3-oxo-3-methoxy-propenyl]-cyclopropane carboxylate and an inert carrier having excellent insecticidal activity and low mammal toxicity.
    Type: Grant
    Filed: June 25, 1993
    Date of Patent: March 28, 1995
    Assignee: Roussel-Uclaf
    Inventors: Jacques Demassey, Jean-Pierre Demoute, Pierre Pastre, Andre Teche
  • Patent number: 5310751
    Abstract: All possible stereoisomer forms and mixtures thereof of a compound of the formula ##STR1## wherein X is halogen, Y is --0-- or --S-- and R is selected from the group consisting of optionally substituted alkyl, alkenyl and alkynyl of up to 8 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, optionally substituted aryl and aralkyl of up to 14 carbon atoms and optionally substituted heterocyclic having pesticidal properties.
    Type: Grant
    Filed: July 1, 1992
    Date of Patent: May 10, 1994
    Assignee: Roussel Uclaf
    Inventors: Didier Babin, Marc Benoit, Jacques Demassey, Jean-Pierre Demoute
  • Patent number: 5262438
    Abstract: All possible stereoisomers and mixtures thereof of a compound of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, fluorine, chlorine and bromine, R is selected from the group consisting of optionally substituted alkyl, alkenyl, alkynyl and cycloalkyl of up to 8 carbon atoms, optionally substituted aryl and aralkyl of up to 14 carbon atoms and optionally substituted heterocyclic and Z is selected from the group consisting of hydrogen, methyl, --CN and --C.tbd.CH having pesticidal, particularly insecticidal properties.
    Type: Grant
    Filed: July 1, 1992
    Date of Patent: November 16, 1993
    Assignee: Roussel-UCLAF
    Inventors: Marc Benoit, Jacques Demassey, Jean-Pierre Demoute
  • Patent number: 5164409
    Abstract: All possible stereoisomers and mixtures of a compound of the formula ##STR1## wherein X and Y are different and are selected from the group consisting of hydrogen, halogen, --CN, alkyl and haloalkyl of 1 to 8 carbon atoms and phenyl optionally substituted by at least one member of the group consisting of halogen and alkyl and alkoxy of 1 to 8 carbon atoms, R.sub.1 is selected from the group consisting of hydrogen, methyl, --CN and ethynyl, ##STR2## A and B are individually selected from the group consisting of hydrogen, halogen, alkyl of 1 to 8 carbon atoms and aryl of 6 to 14 carbon atoms and the --CF.sub.3 is in the 2-, 4- or 5-position of the pyrrole ring having pesticidal activity.
    Type: Grant
    Filed: February 26, 1991
    Date of Patent: November 17, 1992
    Assignee: Roussel Uclaf
    Inventors: Marc Benoit, Jacques Demassey, Jean-Pierre Demoute, Jean Tessier
  • Patent number: 5030655
    Abstract: A compound selected from the group consisting of all possible isomeric forms and mixtures thereof of a compound of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, alkenyl and alkynyl of 2 to 8 carbon atoms and cycloalkyl and cycloalkylalkyl of 3 to 8 carbon atoms, R.sub.2 is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, alkenyl and alkynyl of 2 to 8 carbon atoms, cycloalkyl of 3 to 8 carbon atoms and acyl of 1 to 9 carbon atoms, X.sub.1 and X.sub.2 are individually selected from the group consisting of fluorine, chlorine, bromine, iodine, --CF.sub.3, --CN, --COOR and ##STR2## R is alkyl of 1 to 8 carbon atoms, Hal is chlorine, bromine or fluorine and R.sub.3 is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms and residue of an alcohol used in pyrethrinoid synthesis having excellent pesticidal properties.
    Type: Grant
    Filed: September 25, 1989
    Date of Patent: July 9, 1991
    Assignee: Roussel Uclaf
    Inventors: Jean Tessier, Jacques Demassey, Jean-Pierre Demoute
  • Patent number: 5008281
    Abstract: All stereoisomeric forms and mixtures thereof of a compound of the formula ##STR1## wherein X is --O-- or --S--, Y is --C.dbd.O, ##STR2## or --CH.sub.2 --, R.sub.1 is selected from the group consisting of hydrogen, halogen, optionally unsaturated alkyl of 1 to 8 carbon atoms and optionally unsaturated cycloalkyl of 3 to 8 carbon atoms, the latter two being optionally substituted with one or more halogen and aryl of 6 to 14 carbon atoms, R.sub.2 is selected from the group consisting of hydrogen, --CF.sub.3, --NO.sub.2, --CN, halogen, alkoxy of 1 to 8 carbon atoms, aryl of 6 to 14 carbon atoms, an ester, optionally unsaturated alkyl of 1 to 8 carbon atoms and optionally unsaturated cycloalkyl of 3 to 8 carbon atoms, the latter two being optionally substituted with one or more halogen, R.sub.3 is selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms, --CN and --C.tbd.CH and A is the residue of an ACOOH pyrethrinoid acid having pesticidal properties.
    Type: Grant
    Filed: November 7, 1989
    Date of Patent: April 16, 1991
    Assignee: Roussel Uclaf
    Inventors: Jacques Demassey, Jean-Pierre Demoute, Jean Tessier
  • Patent number: 4939172
    Abstract: Novel cyclopropane carboxylic acid esters of all possible stereoisomeric forms and mixtures thereof of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, fluorine, chlorine and bromine, R is selected from the group consisting of optionally unsaturated alkyl of 1 to 8 carbon atoms optionally substituted, optionally unsaturated cycloalkyl of 3 to 8 carbon atoms optionally substituted, optionally substituted aryl of 6 to 14 carbon atoms and optionally substituted heterocycle, Z is selected from the group consisting of hydrogen, --CH.sub.3, --CN and --C.tbd.CH and Y is selected from the group consisting of hydrogen, --OH, optionally unsaturated alkyl of 1 to 8 carbon atoms optionally substituted, --CN, --(CH.sub.2).sub.m --OAlk, --(CH.sub.2).sub.m --S--Alk, ##STR2## m is 0,1,2,3 or 4, Alk is alkyl of 1 to 12 carbon atoms, --Si(Alk').sub.3, Alk' is optionally unsaturated alkyl of 1 to 8 carbon atoms optionally substituted, --O--Ar and --(CH.sub.2).sub.
    Type: Grant
    Filed: February 8, 1988
    Date of Patent: July 3, 1990
    Assignee: Roussel Uclaf
    Inventors: Joseph Cadiergue, Jacques Demassey, Jean-Pierre Demoute, Jean Tessier
  • Patent number: 4925862
    Abstract: All stereoisomeric forms and mixtures thereof of a compound of the formula ##STR1## wherein X is --O-- or --S--, Y is --C.dbd.O, ##STR2## or --CH.sub.2 --, R.sub.1 is selected from the group consisting of hydrogen, halogen, optionally unsaturated alkyl of 1 to 8 carbon atoms and optionally unsaturated cycloalkyl of 3 to 8 carbon atoms, the latter two being optionally substituted with one or more halogen and aryl of 6 to 14 carbon atoms, R.sub.2 is selected from the group consisting of hydrogen, --CF.sub.3, --NO.sub.2, --CN, halogen, alkoxy of 1 to 8 carbon atoms, aryl of 6 to 14 carbon atoms, an ester, optionally unsaturated alkyl of 1 to 8 carbon atoms and optionally unsaturated cycloalkyl of 3 to 8 carbon atoms the latter two being optionally substituted with one or more halogen, R.sub.3 is selected from the group consisting of hydrogen, alkyl of 1 to 3 carbon atoms, --CN and --C.tbd.CH and A is the residue of an ACOOH pyrethrinoid acid having pesticidal properties.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: May 15, 1990
    Assignee: Roussel Uclaf
    Inventors: Jacques Demassey, Jean-Pierre Demoute, Jean Tessier
  • Patent number: 4849443
    Abstract: A compound of the formula ##STR1## wherein A is the residue of a ACOOH pyrethrinoid acid, Z is selected from the group consisting of hydrogen, --CN, --C.tbd.CH, --CH.sub.3 and alkyl of 1 to 3 carbon atoms, R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms, alkenyl and alkynyl of 2 to 8 carbon atoms, cycloalkyl, cycloalkenyl and cycloalkynyl of 3 to 8 carbon atoms, aryl of 6 to 14 carbon atoms and aralkyl of 7 to 18 carbon atoms and R.sub.2 is selected from the group consisting of hydrogen, halogen, alkyl of 1 to 8 carbon atoms, alkenyl and alkynyl of 2 to 8 carbon atoms, cycloalkyl, cycloalkenyl and cycloalkynyl of 3 to 8 carbon atoms, aryl of 6 to 14 carbon atoms, aralkyl of 7 to 18 carbon atoms, --CN, --CF.sub.3, --NO.sub.2 and --COOAlK and AlK is alkyl of 1 to 18 carbon atoms having pesticidal activities.
    Type: Grant
    Filed: September 14, 1987
    Date of Patent: July 18, 1989
    Assignee: Roussel Uclaf
    Inventors: Jean Tessier, Jacques Demassey, Jean-Pierre Demoute