Abstract: The present invention relates to an implant comprising: —a core material comprising polydimethylsiloxane or at least one hydrogel polymer; —a tube encasing said core material comprising an ethylene vinyl acetate polymer or at least one hydrogel polymer; —a sealant for closure of the open ends of said tube comprising polydimethylsiloxane or a mono-, di-, or triacetoxy derivative thereof, or at least one hydrogel polymer; and —at least one active ingredient; wherein said at least one active ingredient is selected from the group comprising celecoxib, sulindac, tamoxifen, oestrogen, oestradiol, ethinyl oestradiol, mestranol, dienogest, norgestrel, levonorgestrel, desogestrel, norgestimate, ethynodiol diacetate, leuprorelin, buserelin, gonrelin, triptorelin, nafarelin, deslorelin, histrelin, and supprelin; and with the proviso that when the sealant is said at least one hydrogelpolymer, the core material comprises polydimethylsiloxane. Furthermore, the invention relates to an implant for use as a medicament.

Abstract: A medical instrument has a rod-shaped body which has a distal end section which can be inserted through a vagina into an uterus. A bell-shaped element is mounted on the rod-shaped body. The bell-shaped element being slidingly displaceable along said rod-shaped body at least between an axial position on said rod-shaped body close to a proximal end thereof and up to said distal end section inserted in an uterus.

Abstract: The present invention provides for a device comprising a scaffold composition, a bioactive composition and a bio-in-hibiting composition, wherein said bioactive and bio-inhibiting compositions are incorporated into or coated onto said scaffold composition, wherein said scaffold composition temporally supports survival and growth of resident follicles, migration and multiplication of stroma cells and spreading and organization of endothelial cells and new vessels wherein said bioactive composition regulates development of a resident follicle, formation of new blood vessels and chemoattraction and proliferation of stroma cells and wherein the bio-inhibiting composition regulates inhibition of the development of a second resident follicle. The presence of the bio-inhibiting composition within the scaffold is involved in the quiescence of the follicles in the primordial stage, which is important to restore fertility.

Abstract: The present invention concerns hybrid manual-robotic system for supporting and moving a surgical instrument having active main structure (100) that comprises: a) a base (2) for attachment to an operating table having an operating surface (150); b) a hexahedral-shape frame (3), which shape is formed from a first (5, 5?) and second (4, 4?) pair of opposing parallelograms and opposing proximal (6?) and distal (6) rectangles, which frame (3) is formed by at least seven links (7, 8, 9, 10, 11, 12, 13, 22, 23) connected by revolute joints (14, 15, 16, 17, 18, 19, 20, 26, 27, 109), whereby a) a pair of parallel base links (7, 13) of the proximal rectangle (6?) is coupled to the base (2) by two revolute joints (116, 117), and are configured to lie and remain essentially perpendicular to the plane of the 10 operating surface (150) and to revolve around their longitudinal axes that coincide with the axes of revolution of joints (116, 117), whereby b) said revolute joints are configured to allow the hexahedral frame (3)

Abstract: A medical instrument has a rod-shaped body which has a distal end section which can be inserted through a vagina into an uterus. A bell-shaped element is mounted on the rod-shaped body. The bell-shaped element being slidingly displaceable along said rod-shaped body at least between an axial position on said rod-shaped body close to a proximal end thereof and up to said distal end section inserted in an uterus.

Abstract: The present invention relates to a uterine manipulator comprising at least (i) a handle (1) which has a longitudinal axis (10), (ii) an arm (2) which also has a longitudinal axis (20) with a distal end (21) connecting it to the handle (1) and a proximal end (22), and (iii) a head (3) which has a longitudinal axis (30) and which is attached to the proximal end (22) of the arm (2), the shape and length of said arm (2) being sufficient to allow the head (3) of said arm to be introduced into the vaginal cavity, characterized in that said head (3) is provided with a sectioning device (4) arranged on a support (5), allowing the vaginal wall to be sectioned, this sectioning device (4) being arranged at a certain distance from the longitudinal axis (30) of the head (3) and being able to perform a rotating movement, preferably of 360 degrees, about said longitudinal axis (30).

Abstract: A device for treating the interior of a body cavity with laser energy includes an optical fiber having a distal end to be inserted into the body cavity to be treated, and a proximal end to be located externally of the body cavity and to be coupled to a source of laser energy; a second fiber axially movable with respect to the optical fiber and mechanically coupled to its distal end to cause it to move in the lateral direction; and a stiffening spine normally supporting the distal ends of the two fibers in side-by-side relation, but permitting the distal end of one fiber to move laterally with respect to the other fiber.

Abstract: A device for treating the interior of a body cavity with laser energy includes a cannula having a distal end adapted to be inserted into the body cavity to be treated, and a proximal end to be located externally of the body cavity when the distal end is inserted therein, and an optical fiber axially movable within the cannula to either a retracted, non-operative position or to an extended, operative position. The optical fiber has a proximal end to be coupled to a source of laser energy, and a distal end to project outwardly of the cannula in the extended, operative position of the optical fiber. The distal end of the optical fiber has a roughened outer surface for scattering the laser energy laterally outwardly of the optical fiber.