Abstract: Methylpiperazinoazepine derivatives corresponding to formula (I): ##STR1## wherein the symbols X, R.sub.1, R.sub.2, N.sub.1 and N.sub.2 have different meanings and pharmaceutically acceptable salts thereof, preparation and use thereof.

Abstract: This invention relates to new derivatives of 4-amino-3-sulfonamido-pyridine having diuretic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which R.sub.1 represents hydrogen or an alkyl, cycloalkyl, carbamoyl or sulfonamido radical;R.sub.2 represents an alkyl, halogenoalkyl, cycloalkyl, alkenyl, alkynyl, hydroxyalkyl, alkoxyalkyl, phenyl (possibly substituted), phenylalkyl, diphenylmethyl, isobornyl, furfuryl, tetrahydrofurfuryl, dialkylaminoalkyl or heterocyclic radical; or R.sub.1 and R.sub.2 form together with the nitrogen atom a saturated heterocyclic radical; andX represents an alkoxy radical, an heterocyclic amino radical, or a secondary or tertiary amino radical having its first substituent selected from hydrogen and the alkyl and alkenyl groups, and its second substituent selected from the alkyl, alkenyl, alkynyl, hydroxyalkyl, diphenylmethyl, isorbornyl, furfuryl, tetrahydrofurfuryl, phenylalkyl and heterocyclic groups.

Abstract: This invention relates to new derivatives of pyridine having hypo-uricemic or hypolipemic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an oxy or thio group, R.sub.1 represents hydrogen, a group of the formula R.sub.3 NHCO (II), wherein R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, cycloalkyl or possibly substituted phenyl group, or a group of the formula R.sub.4 --CO (III) in which R.sub.4 represents a C.sub.1- C.sub.4 -alkyl group or a possibly substituted phenyl group, and R', R" and R'" represent each a possible substituent selected from the group comprising the halogens, the trifluoromethyl and the C.sub.1- C.sub.4 alkyl groups.

Abstract: This invention relates to new derivatives of 1,2,4-thiadiazine having anti-inflammatory properties.The new derivatives of 1,2,4-thiadiazine may be represented by the following general formula: ##STR1## in which R.sub.1 and Z each represent an unsubstituted or substituted phenyl group.This invention relates also to the N-oxides of the compounds of formula I, as well as to the acid and base addition salts of said compounds.

Abstract: This invention relates to new derivatives of pyridine having anti-inflammatory and diuretic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an amino, C.sub.1 -C.sub.4 -alkylamino, oxy or thio group, R.sub.1 represents a group of the formula R.sub.3 NHCA (II), wherein A represents oxygen or sulfur, and R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, alkenyl, cycloalkyl, phenyl (which may be substituted) or R.sub.4 CO (III) group, R.sub.4 representing a phenyl group (which may be substituted), R.sub.2 represents hydrogen or a C.sub.1 -C.sub.4 alkyl group and Z represents a C.sub.1 -C.sub.4 -alkyl, methylfuryl, pyridyl or phenyl group (which may be substituted).This invention relates also to the N-oxides of the compounds of formula I, as well as to the acid and base addition salts of said compounds.

Abstract: This invention relates to compounds of the formula: ##STR1## wherein R.sub.1 in the 3- or 5-position is a carboxamido group whereas R.sub.2 in the 2-position is a 1-methyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.

Abstract: This invention relates to compounds of the formula: ##SPC1##Wherein R.sub.1 in the 3- or 5-position is preferably a substituted sulfonamido or a carboxamido group whereas R.sub.2 in the 2-, 4- or 6-position is preferably an alkyl- or hydroxyalkyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.

Abstract: This invention relates to compounds of the formula ##SPC1##Wherein R.sub.1 in the 3- or 5-position is a cyano group whereas R.sub.2 and in the 2-position is a N-methyl-piperazinyl group.Said compounds may be used as anti-inflammatory and cardiovascular agents.

Abstract: This invention relates to new derivatives of pyridine having anti-inflammatory and diuretic properties.The new derivatives of pyridine may be represented by the following general formula: ##STR1## in which X represents an amino, C.sub.1 -C.sub.4 -alkylamino, oxy or thio group, R.sub.1 represents a group of the formula R.sub.3 NHCA (II), wherein A represents oxygen or sulfur, and R.sub.3 represents a C.sub.1 -C.sub.4 -alkyl, alkenyl, cycloalkyl, phenyl (which may be substituted) or R.sub.4 CO (III) group, R.sub.4 representing a phenyl group (which may be substituted), R.sub.2 represents hydrogen or a C.sub.1 -C.sub.4 alkyl group and Z represents a C.sub.1 -C.sub.4 -alkyl, methylfuryl, pyridyl or phenyl group (which may be substituted).This invention relates also to the N-oxides of the compounds of formula I, as well as to the acid and base addition salts of said compounds.