Patents by Inventor Jacques Fahy

Jacques Fahy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitrogenated derivatives of pancratistatin
    Patent number: 8697064
    Abstract: The present invention concerns nitrogenated derivatives of narciclasine and pancratistatin of the following general formula (I) as well as their pharmaceutically acceptable salts. The present invention also concerns the use of these compounds in cancer therapy as well as a method for their preparation.
    Type: Grant
    Filed: December 26, 2012
    Date of Patent: April 15, 2014
    Assignee: Pierre Fabre Medicament
    Inventors: Frédéric Marion, Jean-Philippe Annereau, Jacques Fahy
  • Dimeric derivatives of artemisinin and application in anti-cancer therapy
    Patent number: 8614339
    Abstract: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I) below: Formula (I) and the pharmaceutically acceptable salts thereof, and also to the preparation method thereof and to the uses thereof, especially in the treatment of cancer.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: December 24, 2013
    Assignees: Pierre Fabre Medicament, Centre National de la Recherche Scientifique (CNRS), Universite Paris-Sud 11
    Inventors: Jean-Pierre Begue, Danièle Bonnet-Delpon, Benoît Crousse, Anaïs Fournial, Céline Mordant, Jacques Fahy
  • NITROGENATED DERIVATIVES OF PANCRATISTATIN
    Publication number: 20130121986
    Abstract: The present invention concerns nitrogenated derivatives of narciclasine and pancratistatin of the following general formula (I) as well as their pharmaceutically acceptable salts. The present invention also concerns the use of these compounds in cancer therapy as well as a method for their preparation.
    Type: Application
    Filed: December 26, 2012
    Publication date: May 16, 2013
    Inventors: Frederic MARION, Jean-Philippe ANNEREAU, Jacques FAHY
  • Nitrogenated derivatives of pancratistatin
    Patent number: 8415348
    Abstract: The present invention concerns nitrogenated derivatives of narciclasine and pancratistatin of the following general formula (I) as well their pharmaceutically acceptable salts. The present invention also concerns the use of these compounds in cancer therapy as well as a method for their preparation.
    Type: Grant
    Filed: July 28, 2009
    Date of Patent: April 9, 2013
    Assignee: Pierre Fabre Medicament
    Inventors: Frédéric Marion, Jean-Philippe Annereau, Jacques Fahy
  • Dimeric derivatives of artemisinin and application in anticancer therapy
    Patent number: 8236850
    Abstract: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I): or a pharmaceutically acceptable salt thereof with B1 and B2 selected from C?O, CHOH and CH2, as well as to their use in treating cancer and to their preparation method.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: August 7, 2012
    Assignees: Pierre Fabre Medicament, Centre National de la Recherche Scientifique, Universite Paris-Sud 11
    Inventors: Jean-Pierre Begue, Danielle Bonnet-Delpon, Benoît Crousse, Fabienne Grellepois, Constance Chollet, Jacques Fahy, Céline Mordant
  • DIMERIC DERIVATIVES OF ARTEMISININ AND APPLICATION IN ANTI-CANCER THERAPY
    Publication number: 20110152289
    Abstract: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I) below: Formula (I) and the pharmaceutically acceptable salts thereof, and also to the preparation method thereof and to the uses thereof, especially in the treatment of cancer.
    Type: Application
    Filed: July 29, 2009
    Publication date: June 23, 2011
    Applicants: PIERRE FABRE MEDICAMENT, UNIVERSITE PARIS-SUD
    Inventors: Jean-Pierre Begue, Daniele Bonnet-Delpon, Benoit Crousse, Anais Fournial, Celine Mordant, Jacques Fahy
  • NITROGENATED DERIVATIVES OF PANCRATISTATIN
    Publication number: 20110123516
    Abstract: The present invention concerns nitrogenated derivatives of narciclasine and pancratistatin of the following general formula (I) as well their pharmaceutically acceptable salts. The present invention also concerns the use of these compounds in cancer therapy as well as a method for their preparation.
    Type: Application
    Filed: July 28, 2009
    Publication date: May 26, 2011
    Applicant: PIERRE FABRE MEDICAMENT
    Inventors: Frédéric Marion, Jean-Philippe Annereau, Jacques Fahy
  • DIMERIC DERIVATIVES OF ARTEMISININ AND APPLICATION IN ANTICANCER THERAPY
    Publication number: 20100266570
    Abstract: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I): or a pharmaceutically acceptable salt thereof with B1 and B2 selected from C?O, CHOH and CH2, as well as to their use in treating cancer and to their preparation method.
    Type: Application
    Filed: December 22, 2008
    Publication date: October 21, 2010
    Applicants: Pierre Fabre Medicament, Centre National De La Recherche Scientifique, Universite Paris-Sud 11
    Inventors: Jean-Pierre Begue, Danièle Bonnet-Delpon, Benoît Crousse, Fabienne Grellepois, Constance Chollet, Jacques Fahy, Céline Mordant
  • Vinca alkaloid antimitotic halogenated derivatives
    Patent number: 6127377
    Abstract: The invention concerns novel halogenated derivatives of the vinblastine and vinorelbine family, corresponding to general formula (I) and their therapeutically acceptable salts. The invention also concerns the application of these compounds in therapy and their method of preparation. The invention further concerns a novel method for preparing vinflunine or 20',20'-difluoro-3',4'-dihydrovinorelbine, of formula (a).
    Type: Grant
    Filed: October 7, 1999
    Date of Patent: October 3, 2000
    Assignee: Adir et Compagnie
    Inventors: Alain Duflos, Jacques Fahy, Valerie Thillaye du Boullay, Jean-Marc Barret, Bridget Hill
  • Antimitotic binary alkaloid derivatives from catharanthus roseus
    Patent number: 5620985
    Abstract: Novel fluorinated derivatives of the vinblastine and vinorelbine family of general formula (1), ##STR1## wherein the symbols have the meanings indicated in the Specification and Claims, and the therapeutically-acceptable salts of these molecules, as well as pharmaceutical compositions thereof. The invention also concerns the application of said compounds in the treatment of a cancer pathology and their methods of preparation.
    Type: Grant
    Filed: January 19, 1996
    Date of Patent: April 15, 1997
    Assignee: Pierre Fabre Medicament
    Inventors: Jean-Claude Jacquesy, Jacques Fahy, Christian Berrier, Dennis Bigg, Marie-Paule Jouannetaud, Fabien Zunino, Anna Kruczynski, Robert Kiss
  • Process for the preparation of vincristine
    Patent number: 4767855
    Abstract: The present invention relates to a process for the preparation of vincristine.The process for the semisynthesis of vincristine according to the present invention comprises oxidizing vinblastine or its salts with chromic acid or its salts, in ethyl acetate at a low temperature.
    Type: Grant
    Filed: June 2, 1986
    Date of Patent: August 30, 1988
    Assignee: P. F. Medicament
    Inventors: Roger Tarroux, Jacques Fahy, Philippe Hatinguais