Patents by Inventor Jacques Gore

Jacques Gore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8026231
    Abstract: The invention relates to novel aminothiol ester compounds having the general formula (I): and to a method for preparing them and to their use in pharmaceutical compositions intended for use in human or veterinary medicine (cancers and precancers, dermatological, rheumatic and ophthalmological complaints in particular) or in cosmetic compositions. The invention also relates to a pharmaceutical or cosmetic composition, characterized in that it comprises, as active agent, a compound of general formula (I) in combination with a pharmaceutically or cosmetically acceptable support.
    Type: Grant
    Filed: March 28, 2006
    Date of Patent: September 27, 2011
    Assignee: CNRS
    Inventors: Guy Fournet, Gerard Anthony Quash, Jacques Gore
  • Publication number: 20070032476
    Abstract: The invention relates to novel aminothiol ester compounds having the general formula (I): and to a method for preparing them and to their use in pharmaceutical compositions intended for use in human or veterinary medicine (cancers and precancers, dermatological, rheumatic and ophthalmological complaints in particular) or in cosmetic compositions. The invention also relates to a pharmaceutical or cosmetic composition, characterized in that it comprises, as active agent, a compound of general formula (I) in combination with a pharmaceutically or cosmetically acceptable support.
    Type: Application
    Filed: March 28, 2006
    Publication date: February 8, 2007
    Applicant: CNRS - CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Guy Fournet, Gerard Quash, Jacques Gore
  • Patent number: 7078402
    Abstract: The invention relates to novel aminothiol ester compounds having the general formula (I): and to a method for preparing them and to their use in pharmaceutical compositions intended for use in human or veterinary medicine (cancers and precancers, dermatological, rheumatic and ophthalmological complaints in particular) or in cosmetic compositions. The invention also relates to a pharmaceutical or cosmetic composition, characterized in that it comprises, as active agent, a compound of general formula (I) in combination with a pharmaceutically or cosmetically acceptable support.
    Type: Grant
    Filed: May 31, 2001
    Date of Patent: July 18, 2006
    Assignee: Centre National de la Recherche Scientifique (CNRS)
    Inventors: Guy Fournet, Gerard Anthony Quash, Jacques Gore
  • Publication number: 20030181443
    Abstract: The invention relates to novel aminothiol ester compounds having the general formula (I): 1
    Type: Application
    Filed: May 6, 2003
    Publication date: September 25, 2003
    Inventors: Guy Fournet, Gerard Anthony Quash, Jacques Gore
  • Patent number: 6117902
    Abstract: The present invention provides 6,8-Dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical, wherein they correspond to the following formula (I): ##STR1## in which: R represents OR.sub.3 or ##STR2## R.sub.3 representing a hydrogen atom, a linear or branched alkyl radical, or a radical of the formula ##STR3## n being an integer from 1 to 10 and r' and r", which are identical or different, representing a hydrogen atom, a linear or branched alkyl radical or, taken together, form with the nitrogen atom, a nitrogen-containing heterocycle optionally substituted with an optionally substituted oxygen or nitrogen atom,R.sub.5 and R.sub.4, identical or different, represent a hydrogen atom or a linear or branched alkyl radical,R.sub.1 and R.sub.2, which are identical or different, represent a hydrogen atom, a radical --COCH.sub.3 or a radical of formula:--CO(CH.sub.2).sub.2 SCH.sub.3 (II)with the proviso that at least one of the radicals R.sub.1 or R.sub.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: September 12, 2000
    Assignee: Galderman Research & Development, S.N.C. Sophia Abtipolis
    Inventors: Gerard Anthony Quash, Jacques Gore, Guy Fournet
  • Patent number: 4767872
    Abstract: A compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 each independently represent a hydrocarbon gp which can be substituted and/or carry a heteroatom, or R.sub.1 and R.sub.2 together represent a hydrocarbon, optionally substituted, forming with the carbon atom to which they are attached, a ring capable of carrying a heteroatom, R.sub.3 represents hydrogen, lower alkyl or aryl, and R.sub.4 and R.sub.5 each independently represent hydrogen or a hydrocarbon group, as well as the acid addition salts thereof. A method of preparing the compounds and the use thereof as an anti-tumor medicine are disclosed.
    Type: Grant
    Filed: January 31, 1986
    Date of Patent: August 30, 1988
    Assignees: Centre National de la Recherche Scientifique (CNRS), Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Alain Doutheau, Jacques Gore, Gerard A. Quash, Bernard Didier
  • Patent number: 4556742
    Abstract: .alpha.,.delta.-Diethylenic carbonyl compounds of the formula ##STR1## are made by an oxy-Cope rearrangement of an acetylenic alcohol of the formula ##STR2## in the presence of a catalyst based on a metal of Group Ib of the periodic table or palladium. In the formulae (I) and (II), R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be identical or different, each denote a hydrogen atom or a hydrocarbon radical R.sub.2 and R.sub.3 being capable together of forming an alkylene radical (--CH.sub.2 --).sub.n in which one or more carbon atoms may be substituted by one or more alkyl radicals containing 1 to 4 carbon atoms, n is 3 to 20 inclusively and R.sub.5 denotes a hydrogen atom.
    Type: Grant
    Filed: May 25, 1984
    Date of Patent: December 3, 1985
    Assignee: Rhone-Poulenc Sante
    Inventors: Norbert Bluthe, Armand S. Falou, Jacques Gore
  • Patent number: 4510330
    Abstract: Process for the preparation of .delta.-ethylenic carbonyl compounds of the formula: ##STR1## by the oxy-Cope rearrangement of a diethylenic alcohol of the formula: ##STR2## in which the transformation is carried out in the presence of a catalytic amount of a divalent palladium compound.In the depicted formulae R.sub.1, R.sub.4 and R.sub.6 each represent a hydrogen atom or a hydrocarbon radical, R.sub.2 represents a hydrogen atom and R.sub.3 and R.sub.5 each represent a hydrocarbon radical, or R.sub.3 and R.sub.4 together represent an alkylene radical (--CH.sub.2 --).sub.n (wherein n is an integer from 3 to 20 inclusive) in which one or more carbon atoms can optionally carry as substituent(s) one or more alkyl radicals containing 1 to 4 carbon atoms.The carbonyl products are useful as starting materials for the preparation of compounds intended for use in pharmacy, in agriculture or perfumery.
    Type: Grant
    Filed: June 21, 1982
    Date of Patent: April 9, 1985
    Assignee: Rhone-Poulenc Sante
    Inventors: Norbert Bluthe, Jacques Gore, Max Malacria
  • Patent number: 4421934
    Abstract: Process for the preparation of .delta.-ethylenic carbonyl compounds of the formula (I) by the oxy-Cope rearrangement of a diethylenic alcohol of the formula (II), in the presence of a mercuric salt: in formulae (I) and (II), R.sub.1, R.sub.2, R.sub.4, R.sub.5 and R.sub.6, which are identical or different, represent a hydrogen atom or an acyclic hydrocarbon radical and R.sub.3 represents an acyclic hydrocarbon radical, it being understood that R.sub.1 and R.sub.3 can together form a trimethylene radical, or alternatively that R.sub.3 and R.sub.4 can together form an alkylene radical containing 3 to 20 carbon atoms.
    Type: Grant
    Filed: March 5, 1982
    Date of Patent: December 20, 1983
    Assignee: Rhone-Poulenc Sante
    Inventors: Norbert Bluthe, Jacques Gore, Max Malacria