Abstract: This disclosure describes techniques for controlling group access to a collaboration technology. The techniques include generating a shared encryption key among authorized producers of content associated with a collaboration technology. The techniques include receiving, by the authorized producers and from authenticated consumers, requests to access the content. The requests may be received in a partitioned manner, such that individual producers are serving a particular subset of the authenticated consumers. In response to receiving the requests, the techniques include sending the shared encryption key from the individual producers to the corresponding subset of authenticated consumers. The techniques include using the shared encryption key to encrypt content by the authorized producers, which may then be decrypted by the authenticated consumers using the shared encryption key, achieving end-to-end encryption of event content.

Abstract: The invention relates a method to identify genotype at position 171 of the ovine PrP, and a method to select an ovine for reproduction. It also relates kits to implement these methods. The identification method of the invention comprises the steps of treating a sample of ovine biological fluid to be tested containing the PrP with a denaturing and reducing solution, immobilizing the denatured and reduced PrP, optionally via a ligand, on a solid phase, contacting the denatured, reduced and immobilized PrP with at least one detection antibody, and of detecting the possible presence of said at least one detection body, one of the ligand or of said at least one detection antibody specifically binding with the PrP having a particular allelic form at position 171. The invention finds particular application in the medical field, more particularly veterinary and sanitary fields.

Abstract: The invention relates to a method for diagnosing a transmissible spongiform subacute encephalopathy (TSSE) caused by an unconventional transmissible agent (UTA) or prion. The method involves treating a sample suspected of containing a prion with proteinase K for a time and under conditions that completely degrade normal prion protein (Prp-sen), but which only partially digest abnormal prion protein (PrP-res) so that all or some of the octapeptide motif repeats comprising P(H/Q)GGG(-/T)WGQ (SEQ ID NO: 1) in the abnormal prion protein (Prp-res) are retained.

Abstract: The invention relates to a method for diagnosing a transmissible spongiform subacute encephalopathy (TSSE) caused by an unconventional transmissible agent (UTA) or prion. The method involves treating a sample suspected of containing a prion with proteinase K for a time and under conditions that completely degrade normal prion protein (Prp-sen), but which only partially digest abnormal prion protein (PrP-res) so that all or some of the octapeptide motif repeats comprising P(H/Q)GGG(-/T)WGQ (SEQ ID NO: 1) in the abnormal prion protein (Prp-res) are retained.

Abstract: This detection method uses a solid support whereon plasminogen is immobilized, and includes essentially the following steps: (a) preparing the biological sample during which the latter is incubated on a homogenizing buffer which comprises an ionic or nonionic surfactant, a glucose-containing buffer, a saccharose-based buffer and a PBS buffer or in a capture buffer comprising an ionic surfactant; said step optionally comprising incubation with a proteinase K at a final concentration ranging between 1 and 8 ?g/ml; (b) capturing the PrPres on the solid support, which is carried out in the presence of a capture buffer, as defined above; (c) a controlled denaturation of the PrPres fixed on the support comprising incubation with a denaturation buffer including at least one chaotropic agent, at a temperature ranging between room temperature and 100° C.; and (d) detecting the denatured PrPres fixed on said support with a PrP protein-specific antibody.

Abstract: The invention concerns a method for heterogeneous phase detection of an analyte, the trifunctional reagent used for implementing said method, its use for detecting an analyte, as well as the device for detecting a corresponding analyte

Abstract: The invention relates to a method for diagnosing a transmissible spongiform subacute encephalopathy (TSSE) caused by an unconventional transmissible agent (UTA) or prion. The method involves treating a sample suspected of containing a prion with proteinase K for a time and under conditions that completely degrade normal prion protein (Prp-sen), but which only partially digest abnormal prion protein (PrP-res) so that all or some of the octapeptide motif repeats comprising P(H/Q)GGG(?/T)WGQ (SEQ ID NO: 1) in the abnormal prion protein (Prp-res) are retained.

Abstract: The invention concerns a method for detection and quantitative analysis of nucleic acid molecules comprising a step which consists in extraction and random fractionation of said molecules with a strong base and applications thereof.

Abstract: Compound labelled by the acetyl cholinesterase of Electrophorus electricus, its preparation process and its use in enzymoimmunology.This compound is constituted by a molecule chosen from among the antigens, haptens and antibodies, bonded by a covalent bond to an enzyme formed by the acetyl cholinesterase of Electrophorus electricus (electric eel).For example, the molecule is the substance P or a prostaglandin and the compound can be used for the enzymoimmunological determination of these molecules.