Patents by Inventor Jacques Haiech

Jacques Haiech has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridazine compounds, compositions and methods
    Patent number: 9663493
    Abstract: The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: May 30, 2017
    Assignees: Northwestern University, Universite De Strasbourg, Centre National De La Recherche Scientifique (CNRS)
    Inventors: D. Martin Watterson, Linda Van Eldik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Velentza, Wenhui Hu, Magdalena Zasadzki
  • Pyridazine compounds, compositions and methods
    Patent number: 9527819
    Abstract: The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: December 27, 2016
    Assignees: NORTHWESTERN UNIVERSITY, UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: D. Martin Watterson, Linda Van Eldik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Velentza, Wenhui Hu, Magdalena Zasadzki
  • PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS
    Publication number: 20160326139
    Abstract: The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Application
    Filed: June 29, 2016
    Publication date: November 10, 2016
    Applicants: NORTHWESTERN UNIVERSITY, UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: D. Martin WATTERSON, Linda VAN ELDIK, Jacques HAIECH, Marcel HIBERT, Jean-Jacques BOURGUIGNON, Anastasia VELENTZA, Wenhui HU, Magdalena ZASADZKI
  • PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS
    Publication number: 20150175555
    Abstract: The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Application
    Filed: December 3, 2014
    Publication date: June 25, 2015
    Applicants: NORTHWESTERN UNIVERSITY, UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: D. Martin WATTERSON, Linda VAN ELDIK, Jacques HAIECH, Marcel HIBERT, Jean-Jacques BOURGUIGNON, Anastasia VELENTZA, Wenhui HU, Magdalena ZASADZKI
  • Pyridazine compounds, compositions and methods
    Patent number: 8933076
    Abstract: The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for, research, drug screening, and therapeutic applications.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: January 13, 2015
    Assignees: Centre National de la Recherche Scientifique (CNRS), Northwestern University, Universite de Strasbourg
    Inventors: D. Martin Watterson, Linda Van Eldik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Velentza, Wenhui Hu, Magdalena Zasadzki
  • BIOMARKER FOR CHRONIC INFLAMMATORY LUNG DISEASES
    Publication number: 20140371099
    Abstract: The invention relates to an in vitro method for the diagnosis and/or prognosis and/or evaluation of the progression of a chronic inflammatory lung disease in a subject, using the level of expression of the GPR15 G protein-coupled receptor gene as a biomarker for the disease.
    Type: Application
    Filed: January 31, 2013
    Publication date: December 18, 2014
    Inventors: Nelly Frossard, Jacques Haiech, Christine Lehalle, Romain Kessler, Antoine Magnan, Pascal Chanez, Jean-Luc Galzi
  • BISACODYL AND ITS ANALOGUES AS DRUGS FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20140186872
    Abstract: The present invention provides compounds having the formula A: (A) or pharmaceutically acceptable salt thereof, wherein W, R1, R2 and R5 are as defined in classes and subclasses herein, and pharmaceutical compositions thereof, as described generally and in subclasses herein, which compounds are useful as cytotoxic agents towards proliferating and/or quiescent cancer stem cells, and thus are useful, for example, for the treatment of cancer.
    Type: Application
    Filed: June 6, 2012
    Publication date: July 3, 2014
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE- CNRS, UNIVERSITE DE STRASBOURG
    Inventors: Marie Feve, Maria Zeniou-Meyer, Jacques Haiech, Herve Chneiweiss, Marie-Claude Kilhoffer, Samir Mameri, Marcel Hibert
  • Pyridazine compounds, compositions and methods
    Patent number: 8367672
    Abstract: The invention relates to novel chemical compounds and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: February 5, 2013
    Assignees: Universite de Strasbourg, Northwestern University, Centre National de la Recherche Scientifique (CNRS)
    Inventors: D. Martin Watterson, Linda J. Van Eldik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Velentza, Wenhui Hu, Magdalena Zasadzki
  • PYRIDAZINE COMPOUNDS, COMPOSITIONS AND METHODS
    Publication number: 20120245125
    Abstract: The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of making and using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for, research, drug screening, and therapeutic applications.
    Type: Application
    Filed: June 8, 2012
    Publication date: September 27, 2012
    Applicants: Northwestern University
    Inventors: D. Martin Watterson, Linda Van Eldik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Velentza, Wenhui Hu, Magdalena Zasadzki
  • Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
    Patent number: 8088774
    Abstract: A novel class of pyridazine compositions and related methods of use.
    Type: Grant
    Filed: July 7, 2010
    Date of Patent: January 3, 2012
    Assignees: Northwestern University, Universite de Strasbourg, Centre National de la Recherche Scientifique, A Scientific Research Centre
    Inventors: Daniel Martin Watterson, Anu R. Sawkar, Thomas J. Lukas, Salida Mirzoeva, Linda J. Van Eldik, Marcel Hibert, Anastasia Velentza, Magdalena Zasadzki, Jacques Haiech, Jean-Jacques Bourguignon
  • Pyridazine compounds and methods
    Patent number: 8063047
    Abstract: The invention relates to novel chemical compounds of Formula I compositions and methods of using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Grant
    Filed: May 12, 2008
    Date of Patent: November 22, 2011
    Assignees: Centre National de la Recherche Scientifique (CNRS), Northwestern University, Universite de Strasbourg
    Inventors: Martin Watterson, Linda Van El Dik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Veleniza, Wenhui Hu, Magdaena Zasadzki
  • Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
    Patent number: 7888357
    Abstract: A novel class of pyridazine compositions and related methods of use.
    Type: Grant
    Filed: October 26, 2005
    Date of Patent: February 15, 2011
    Assignees: Northwestern University, Universite de Strasbourg, Centre National de la Recherche Scientifique
    Inventors: Daniel Martin Watterson, Anastasia Velentza, Magdalena Zasadzki, Jacques Haiech, Jean-Jacques Bourguignon, Anu R. Sawkar, Thomas J. Lukas, Salida Mirzoeva, Linda J. Van Eldik, Marcel Hibert
  • Novel Compounds Which Interact With PEA-15
    Publication number: 20090170749
    Abstract: The present invention relates to novel pseudopeptide compounds of defined formula, capable of interacting with the PEA-15 protein and to the use thereof in screening methods and to a method of diagnosing pathological conditions which may involve PEA-15.
    Type: Application
    Filed: December 15, 2006
    Publication date: July 2, 2009
    Applicant: Institut National De La Sante Et De La Recherche Medicale (Inserm)
    Inventors: Marcel Hibert, Hadjila Chabane, Dominique Bonnet, Jacques Haiech, Francois Renault-Mihara, Hervé M. Chneiweiss
  • PYRIDAZINE COMPOUNDS AND METHODS
    Publication number: 20090029985
    Abstract: The invention relates to novel chemical compounds, compositions and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Application
    Filed: May 12, 2008
    Publication date: January 29, 2009
    Inventors: Martin Watterson, Linda Van El Dik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Valeniza, Wenhui Hu, Magdena Zasadzki
  • Pyridazine Compounds, Compositions and Methods
    Publication number: 20080318899
    Abstract: The invention relates to novel chemical compounds and methods of making and using the same. In particular, the invention provides pyridazine compounds and/or related heterocyclic derivatives, compositions comprising the same, and methods of using pyridazine compounds and/or related heterocyclic derivatives and compositions comprising the same, for modulation of cellular pathways (e.g., signal transduction pathways), for treatment or prevention of inflammatory diseases (e.g., Alzheimer's disease), for research, drug screening, and therapeutic applications.
    Type: Application
    Filed: November 2, 2005
    Publication date: December 25, 2008
    Inventors: Martin Watterson, Linda Van Eldik, Jacques Haiech, Marcel Hibert, Jean-Jacques Bourguignon, Anastasia Velentza, Wenhui Hu, Magdelena Zasadzki
  • Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
    Publication number: 20060073472
    Abstract: A novel class of pyridazine compositions and related methods of use.
    Type: Application
    Filed: October 26, 2005
    Publication date: April 6, 2006
    Inventors: D. Watterson, Anastasia Velentza, Magdalena Zasadzki, Jacques Haiech, Jean-Jacques Bourguignon, Anu Sawkar, Thomas Lukas, Salida Mirzoeva, Linda Van Eldik, Marcel Hibert
  • Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
    Publication number: 20030176437
    Abstract: A novel class of pyridazine compositions and related methods of use.
    Type: Application
    Filed: September 3, 2002
    Publication date: September 18, 2003
    Inventors: D.M. Watterson, Anu R. Sawkar, Thomas J. Lukas, Salida Mirzoeva, Linda J. Van Eldik, Marcel Hibert, Anastasia Velentza, Magdalena Zasadzki, Jacques Haiech, Jean-Jacques Bourguignon