Patents by Inventor Jacques Huck

Jacques Huck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and pharmaceutical compositions thereof for the treatment of proliferative disorders
    Patent number: 9062051
    Abstract: The present invention discloses compounds according to Formula I: wherein R1, R2, R3, R4, L, and X are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and their use in the prophylaxis and/or treatment of inflammatory conditions, type 2 diabetes, neurological and/or neurodegenerative diseases, autoimmune diseases, proliferative diseases (in particular metastatic diseases, and/or cancer), abnormal angiogenesis associated diseases, degradation of cartilage, and/or disruption of cartilage homeostasis, in particular in the prophylaxis and/or treatment of cancer. The present invention also discloses methods of treatment using the same compounds, for the prophylaxis and/or treatment of said diseases by administering the compound of the invention.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: June 23, 2015
    Assignee: GALAPAGOS NV
    Inventors: Laurent Raymond Maurice Sanière, Jacques Huck, Graeme James Dykes, Benoit Antoine Schmitt, Javier Blanc, Anna Sara Butler, Florence Marie-Emilie Bonnaterre, Stéphane Nicolas Alain Beaumont
  • NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20150080391
    Abstract: The present invention discloses compounds according to Formula I: wherein R1, R2, R3, R4, L, and X are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and their use in the prophylaxis and/or treatment of inflammatory conditions, type 2 diabetes, neurological and/or neurodegenerative diseases, autoimmune diseases, proliferative diseases (in particular metastatic diseases, and/or cancer), abnormal angiogenesis associated diseases, degradation of cartilage, and/or disruption of cartilage homeostasis, in particular in the prophylaxis and/or treatment of cancer. The present invention also discloses methods of treatment using the same compounds, for the prophylaxis and/or treatment of said diseases by administering the compound of the invention.
    Type: Application
    Filed: August 18, 2014
    Publication date: March 19, 2015
    Inventors: Laurent Raymond Maurice SANIÈRE, Jacques HUCK, Graeme James DYKES, Benoit Antoine SCHMITT, Javier BLANC, Anna Sara BUTLER, Florence Marie-Emilie BONNATERRE, Stéphane Nicolas Alain BEAUMONT
  • Use of Piperidine Derivatives as Agonists of Chemokine Receptor Activity
    Publication number: 20090054451
    Abstract: The present invention is directed to novel piperidine derivatives and to the use of piperidine derivatives of formula I as agonists of chemokine receptor activity.
    Type: Application
    Filed: August 4, 2008
    Publication date: February 26, 2009
    Applicant: Euroscreen S.A.
    Inventors: Jacques Huck, Frederic Ooms, Christian Tyrchan, Hamid R. Hoveyda
  • Novel Piperidine-4-Acetic Acid Derivatives and Their Use
    Publication number: 20090048291
    Abstract: The present invention is directed to compounds of formula I compositions comprising them and their use.
    Type: Application
    Filed: August 4, 2008
    Publication date: February 19, 2009
    Applicant: Euroscreen S.A.
    Inventors: Jacques Huck, Frederic Ooms, Julien Parcq, Regereau Yannick, Hamid R. Hoveyda, Guillaume Dutheuil