Patents by Inventor Jacques J. Peschon

Jacques J. Peschon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IL-17 receptor A antigen binding proteins
    Patent number: 11858999
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Grant
    Filed: August 5, 2020
    Date of Patent: January 2, 2024
    Assignee: AMGEN K-A, INC.
    Inventors: Joel E. Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • IL-17 Receptor A antigen binding proteins
    Patent number: 11180564
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: November 23, 2021
    Assignee: AMGEN K-A, INC.
    Inventors: Joel E. Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
    Publication number: 20200362045
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Application
    Filed: August 5, 2020
    Publication date: November 19, 2020
    Inventors: Joel E. Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
    Publication number: 20200017591
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Application
    Filed: December 21, 2018
    Publication date: January 16, 2020
    Inventors: Joel E. Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • IL-17 receptor A antigen binding proteins
    Patent number: 10208122
    Abstract: Disclosed is an isolated human monoclonal antibody that specifically binds IL-17 Receptor A, or an IL-17 Receptor A binding fragment thereof, and inhibits IL-17A from binding and activating the receptor. The present disclosure also provides compositions and methods for treating diseases mediated by IL-17 Receptor A activation.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: February 19, 2019
    Assignee: AMGEN K-A, INC.
    Inventors: Joel E. Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
    Publication number: 20160251443
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Application
    Filed: March 2, 2016
    Publication date: September 1, 2016
    Inventors: Joel E. Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • IL-17 receptor A antigen binding proteins
    Patent number: 9096673
    Abstract: The present invention relates to IL-17 Receptor A antigen binding proteins, such as antibodies, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation.
    Type: Grant
    Filed: March 10, 2011
    Date of Patent: August 4, 2015
    Assignee: KIRIN-AMGEN, INC.
    Inventors: Joel Tocker, Jacques J. Peschon, James F. Smothers
  • IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
    Publication number: 20140356355
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Application
    Filed: June 13, 2014
    Publication date: December 4, 2014
    Inventors: Joel E. Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • Methods of treating psoriasis using IL-17 receptor A antibodies
    Patent number: 8790648
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: July 29, 2014
    Assignee: Amgen Inc.
    Inventors: Joel Tocker, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • Polynucleotides encoding IL-17 receptor A antigen binding proteins
    Patent number: 8545842
    Abstract: The present invention relates to IL-17 receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, and the polynucleotide sequences encoding them, as well as host cells, expression vectors, and methods of making IL-17 receptor A antigen binding proteins.
    Type: Grant
    Filed: June 25, 2010
    Date of Patent: October 1, 2013
    Assignee: Kirin-Amgen, Inc.
    Inventors: Joel Tocker, Jacques J. Peschon, James F. Smothers
  • Methods of using IL-17 receptor a antibodies
    Patent number: 8435518
    Abstract: The present invention relates to IL-17 Receptor A antigen binding proteins, such as antibodies, and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: May 7, 2013
    Assignee: Kirin-Amgen, Inc.
    Inventors: Joel Tocker, Jacques J. Peschon, David Fitzpatrick
  • IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
    Publication number: 20120251547
    Abstract: The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.
    Type: Application
    Filed: May 15, 2012
    Publication date: October 4, 2012
    Applicant: Amgen, Inc.
    Inventors: Joel TOCKER, Jacques J. Peschon, David Fitzpatrick, James F. Smothers, Christopher Mehlin, Ai Ching Lim
  • IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
    Publication number: 20110166331
    Abstract: The present invention relates to IL-17 Receptor A antigen binding proteins, such as antibodies, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation.
    Type: Application
    Filed: March 10, 2011
    Publication date: July 7, 2011
    Applicant: Amgen, Inc.
    Inventors: Joel TOCKER, Jacques J. Peschon, James F. Smothers
  • IL-17 receptor A antigen binding proteins
    Patent number: 7939070
    Abstract: The present invention relates to IL-17 Receptor A antigen binding proteins, such as antibodies, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: May 10, 2011
    Assignee: Amgen Inc.
    Inventors: Joel Tocker, Jacques J. Peschon, James F. Smothers
  • METHODS OF USING IL-17 RECEPTOR A ANTIBODIES
    Publication number: 20110081339
    Abstract: The present invention relates to IL-17 Receptor A antigen binding proteins, such as antibodies, and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation.
    Type: Application
    Filed: October 6, 2010
    Publication date: April 7, 2011
    Applicant: AMGEN INC.
    Inventors: JOEL TOCKER, JACQUES J. PESCHON, DAVID FITZPATRICK
  • POLYNUCLEOTIDES ENCODING IL-17 RECEPTOR A ANTIGEN BINDING PROTEINS
    Publication number: 20110008841
    Abstract: The present invention relates to IL-17 receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, and the polynucleotide sequences encoding them, as well as host cells, expression vectors, and methods of making IL-17 receptor A antigen binding proteins.
    Type: Application
    Filed: June 25, 2010
    Publication date: January 13, 2011
    Applicant: Amgen Inc.
    Inventors: Joel TOCKER, Jacques J. Peschon, James F. Smothers
  • IL-17 HETEROMERIC RECEPTOR COMPLEX
    Publication number: 20110008356
    Abstract: The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor C form a heteromeric receptor complex that is biologically active.
    Type: Application
    Filed: June 13, 2008
    Publication date: January 13, 2011
    Applicant: AMGEN, INC.
    Inventors: Jacques J. Peschon, Joel Tocker, Dean Toy
  • Methods of treating psoriasis using IL-17 Receptor A antibodies
    Patent number: 7833527
    Abstract: The present invention relates to IL-17 Receptor A antigen binding proteins, such as antibodies, and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: November 16, 2010
    Assignee: Amgen Inc.
    Inventors: Joel Tocker, Jacques J. Peschon, David Fitzpatrick
  • Polynucleotides encoding IL-17 receptor A antigen binding proteins
    Patent number: 7786284
    Abstract: The present invention relates to IL-17 receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, and the polynucleotide sequences encoding them, as well as host cells, expression vectors, and methods of making IL-17 receptor A antigen binding proteins.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: August 31, 2010
    Assignee: Amgen Inc.
    Inventors: Joel Tocker, Jacques J. Peschon, James F. Smothers
  • METHODS FOR TREATING AUTOIMMUNE AND CHRONIC INFLAMMATORY CONDITIONS USING ANTAGONISTS OF CD30 OR CD30L
    Publication number: 20100071079
    Abstract: The invention provides methods of treating autoimmune and chronic inflammatory conditions by administering agents that hinder the CD30/CD30L interaction, combination treatments, and methods of treating conditions resistant to treatment with TNF? inhibitors by administering agents that inhibit signal transduction by CD30 or IL-1. Included also are treatments involving concurrently administering agents that block the CD30/CD30L interaction and agents that antagonize the IL-4/IL-4R interaction. Additionally provided is an animal model for screening candidate agents for their efficacy in treating conditions that are resistant to treatment with TNF? inhibitors.
    Type: Application
    Filed: November 10, 2009
    Publication date: March 18, 2010
    Applicant: Immunex Corporation
    Inventors: Kendall M. MOHLER, Dauphine S. Barone, Jacques J. Peschon, Mary K. Kennedy, John D. Pluenneke