Abstract: A solution of gamma-globulins, coming for example from Cohn's fractionation, is submitted to a step of fractionation with polyethylene-glycol, a step of moderated enzymatic treatment with pepsin, plasmin or papain, and a step of PEG elimination.

Abstract: Procedure for the preparation of a concentrate of prothrombinogenic compound.This procedure, in which, starting from a source of prothrombinogenic compound, an adsorption is followed by an elution, is characterized by the fact that a source of prothrombinogenic compound and a source of antithrombin III (or AT III) is placed in contact with an adsorbing agent capable of adsorbing both the prothrombinogenic compound and antithrombin III, and that the foregoing occurs in the presence of heparin, at least during the elution stage, and that elution is carried out with an elution agent capable of eluting the prothrombinogenic compound, the AT III and heparin at the same time.Application of the product obtained, notably to the treatment of blood coagulation difficulties.

Abstract: An improved process for preparing factor VIII concentrate which comprises a first stage wherein fibrinogen is precipitated from a buffered plasma or plasma cryoprecipitate solution by the addition of a polyol and a second stage where factor VIII is precipitated from the resulting supernatant also by the addition of a polyol. The improvement in the first stage resides in adding the polyol in an amount of 1-3% and maintaining the temperature of the buffered solution between about 2.degree.-4.degree. C.

Abstract: Purified albumin is prepared from frozen placenta, placental blood or other hemolyzed blood by the steps of eliminating hemoglobin, eliminating enzymes and eliminating group substances.