Abstract: The present invention relates to a compound of formula (I), or a tautomer, a stereoisomer, a hydrate, a solvate, a polymorph, a prodrug, an isotope, or a co-crystal thereof, or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3 and R4 are as defined in the description and claims. The present invention also relates to a pharmaceutical composition comprising a compound according to the invention, and a pharmaceutical acceptable carrier. The present invention also relates to the present compounds for use as a medicine and/or as diagnostics. The present invention also relates to the present compounds for use in the prevention and/or treatment of GPR17 mediated disorders, such as for example a disorder or syndrome selected from a myelination disorder and a disorder or syndrome associated with brain tissue damage.

Abstract: A method, system and computer program product for estimating degradation and durability characteristics of a reinforced concrete structure are provided. Location-dependent information conveying structural information associated with different locations along the concrete structure is received, the location-dependent information having been obtained by applying a non-destructive testing (NDT) process to the concrete structure. The location-dependent information is processed in combination with information conveying material properties and information conveying estimated environmental conditions to derive concrete degradation simulation data conveying estimated degradation and durability characteristics associated with the different locations along the concrete structure. A signal is then released, causing the estimated degradation and durability characteristics of the concrete structure to be displayed on a display device.

Abstract: An aircraft engine module handling assembly including a carriage, a pivoting portion at a top of the carriage, a module support tooling, and an additional mechanism for assembly of the tooling on the pivoting portion, such that the module can be rotated from an original vertical position, observed when it reaches an assembly shop in a crate, to a horizontal position suitable for its assembly with another module of an engine.

Abstract: A carriage configured to transport an aircraft engine module from a preparation station to an assembly station includes, on a dolly, a reinforcement structure configured to be made horizontally mobile by sliding on balls, two vertically mobile brackets, and moving fingers to slide under the module's supports. The module is then supported by the carriage in a safe manner, can be raised and transported, and can also be temporarily overturned to check that its interior is empty.

Abstract: A method, system and computer program product for estimating degradation and durability characteristics of a reinforced concrete structure are provided. Location-dependent information conveying structural information associated with different locations along the concrete structure is received, the location-dependent information having been obtained by applying a non-destructive testing (NDT) process to the concrete structure. The location-dependent information is processed in combination with information conveying material properties and information conveying estimated environmental conditions to derive concrete degradation simulation data conveying estimated degradation and durability characteristics associated with the different locations along the concrete structure. A signal is then released, causing the estimated degradation and durability characteristics of the concrete structure to be displayed on a display device.

Abstract: The present invention relates to systems and methods for providing steam to a gas recovery unit 130 based on changes to steam flow to and/or power generated by a power generation unit 119. The gas recovery unit 130 may part of a thermal power generation unit 100 and may be an amine based CO2 recovery unit including two or more regenerator columns 153.

Abstract: The present invention relates to systems and methods for controlling the flow of steam provided to a gas recovery unit 130 based on changes to steam flow to and/or power generated by a power generation unit 119. The gas recovery unit 130 may be part of a thermal power generation unit and may be an amine based CO2 recovery unit including two or more regenerator columns 153.

Abstract: A carriage configured to transport an aircraft engine module from a preparation station to an assembly station includes, on a dolly, a reinforcement structure configured to be made horizontally mobile by sliding on balls, two vertically mobile brackets, and moving fingers to slide under the module's supports. The module is then supported by the carriage in a safe manner, can be raised and transported, and can also be temporarily overturned to check that its interior is empty.

Abstract: An aircraft engine module handling assembly including a carriage, a pivoting portion at a top of the carriage, a module support tooling, and an additional mechanism for assembly of the tooling on the pivoting portion, such that the module can be rotated from an original vertical position, observed when it reaches an assembly shop in a crate, to a horizontal position suitable for its assembly with another module of an engine.

Abstract: The present invention relates to a method of controlling a power plant, which power plant comprises: a boiler being adapted for combusting an organic fuel and for generating steam and a process gas comprising carbon dioxide; a steam system being; and a carbon dioxide capture system being adapted to remove at least a portion of the carbon dioxide from the process gas by contacting a carbon dioxide absorbent solution with the process gas, the method comprising: forwarding a portion of the steam produced by the power plant boiler to a regenerator of the carbon dioxide capture system; regenerating the absorbent solution in said regenerator through heating of said carbon dioxide absorbent solution by means of the forwarded steam; and automatically controlling the operation of the carbon capture system by means of at least one automatic controller. The invention also relates to a power plant including a carbon dioxide capture system.

Abstract: A timepiece has a portion of its case body capable of being removed from the rest of the case body. The removable portion bears an interchangeable dial plate. The device is configured in such a manner that the dial plate never serves as a stopping abutment when it is inserted in the timepiece. A closure device allows the interchangeable dial to be suitably fastened to the watch.

Abstract: The present invention relates to a computational tool that allows to evaluate the degradation of cement-based materials under various types of chemical attacks such as sulfates, chlorides, and plain water. It is based on the physical principles of ionic mass conservation and chemical equilibrium between a solution and different solid phases. The effect of the dissolution or the precipitation of solid phases on the transport coefficients is considered. A method for determining an ion concentration in solution of at least two ions capable of undergoing transport in a cement-based material under a chemical attack and a solid phase profile for at least one component of said cement-based material is provided. A method for determining a diffusion coefficient for each of at least two ions capable of undergoing transport in a cement-based material is also provided.

Abstract: A timepiece has a portion of its case body capable of being removed from the rest of the case body. The removable portion bears an interchangeable dial plate. The device is configured in such a manner that the dial plate never serves as a stopping abutment when it is inserted in the timepiece. A closure device allows the interchangeable dial to be suitably fastened to the watch.

Abstract: The present invention relates to a computational tool that allows to evaluate the degradation of cement-based materials under various types of chemical attacks such as sulfates, chlorides, and plain water. It is based on the physical principles of ionic mass conservation and chemical equilibrium between a solution and different solid phases. The effect of the dissolution or the precipitation of solid phases on the transport coefficients is considered. A method for determining an ion concentration in solution of at least two ions capable of undergoing transport in a cement-based material under a chemical attack and a solid phase profile for at least one component of said cement-based material is provided. A method for determining a diffusion coefficient for each of at least two ions capable of undergoing transport in a cement-based material is also provided.