Patents by Inventor Jacques Martinerie

Jacques Martinerie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10939838
    Abstract: The invention relates to a method for detecting a physiological state of a patient deviating from a reference physiological state, in which, after having determined, in each of Q frequency bands, R reference matrices PRq,r with qe[1 . . . Q] and r?[1 . . . R] which correspond to the reference physiological state, the following steps are repeated in a loop: carrying out measurements, in M time segments, of an electroencephalographic signal; filtering and centering the measurements in Q frequency bands to obtain and determine M×Q scaled matrices of spatial covariance; for each time segment m, calculating a deviation from the reference physiological state, and comparing each of the deviations from the reference physiological state to a predefined threshold. The invention also relates to a monitoring device applying said method.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: March 9, 2021
    Assignees: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, FONDATION ICM—INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Thomas Similowski, Mathieu Raux, Mario Chavez, Jacques Martinerie, Pierre Pouget
  • Publication number: 20150119745
    Abstract: The invention relates to a method for detecting a physiological state of a patient deviating from a reference physiological state, in which, after having determined, in each of Q frequency bands, R reference matrices PRq,r with qe[1 . . . Q] and r?[1 . . . R] which correspond to the reference physiological state, the following steps are repeated in a loop: carrying out measurements, in M time segments, of an electroencephalographic signal; filtering and centering the measurements in Q frequency bands to obtain and determine M×Q scaled matrices of spatial covariance; for each time segment m, calculating a deviation from the reference physiological state, and comparing each of the deviations from the reference physiological state to a predefined threshold. The invention also relates to a monitoring device applying said method.
    Type: Application
    Filed: May 3, 2013
    Publication date: April 30, 2015
    Applicants: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, FONDATION ICM- INSTITUT DU CERVEAU ET DE LA MOELLE EPINIERE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS
    Inventors: Thomas Similowski, Mathieu Raux, Mario Chavez, Jacques Martinerie, Pierre Pouget
  • Patent number: 7697979
    Abstract: A method for analyzing synchronizations of the electroencephalography of an individual using a set of sensors starting from cerebral electromagnetic analysis of the individual. The method creates a database by acquisition and digitization of electrophysiological signals output from the sensors, and calculates the degree of synchronization existing between all pairs of sensors recorded in an assembly protocol, in frequency bands between 0 and 2000 Hz, to build up the database of classes each characterizing a reference state. The method further performs statistical validation of a period analyzed in real time, which assigns this period to a class in the database, and detects a specific period with a determined degree of synchronization. A device implements this method.
    Type: Grant
    Filed: October 14, 2003
    Date of Patent: April 13, 2010
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Jacques Martinerie, Michel Le Van Quyen, Jean-Philippe Lachaux, Bernard Renault
  • Publication number: 20090054800
    Abstract: The invention relates to a method of representing a dynamic functional image of the brain. It consists in acquiring (A) for a specific duration a plurality of electrophysiological signals {esi}1N of cerebral activity from a set of electrodes {Ei}1N placed on the scalp (S) of the subject, in locating (B) the set of neuroelectric generators {{right arrow over (g)}jk}11JK in the cerebral volume from a three-dimensional image {Ck}1K made up of successive cross-sections of the brain, and in applying the inverse problem, and within active zones that include neuroelectric generators discriminating (C) the amount of synchrony that exists between electrophysiological signal and neuroelectric generator pairs in a plurality of frequency bands, to detect groups of discriminating neural networks {RNdk}1K. The invention is useful for non-invasive study of provoked or unprovoked functional anomalies.
    Type: Application
    Filed: July 10, 2006
    Publication date: February 26, 2009
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS-
    Inventors: Jacques Martinerie, Sylvain Baillet, Line Garnero, Jean-Philippe Lachaux, Michel Le Van Quyen, Bernard Renault
  • Publication number: 20060015034
    Abstract: A method for analyzing synchronizations of the electroencephalography of an individual using a set of sensors starting from cerebral electromagnetic analysis of the individual. The method creates a database by acquisition and digitization of electrophysiological signals output from the sensors, and calculates the degree of synchronization existing between all pairs of sensors recorded in an assembly protocol, in frequency bands between 0 and 2000 Hz, to build up the database of classes each characterizing a reference state. The method further performs statistical validation of a period analyzed in real time, which assigns this period to a class in the database, and detects a specific period with a determined degree of synchronization. A device implements this method.
    Type: Application
    Filed: October 14, 2003
    Publication date: January 19, 2006
    Inventors: Jacques Martinerie, Michel Le Van Quyen, Jean-Philippe Lachaux, Bernard Renault
  • Patent number: 6507754
    Abstract: The invention concerns a device and a method for the detection of changes in dynamic properties of electrical brain activity to characterize and to differentiate between physiological and pathological conditions, or to anticipate epileptic seizures.
    Type: Grant
    Filed: January 17, 2002
    Date of Patent: January 14, 2003
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Michel Le Van Quyen, Jacques Martinerie, Francisco Varela, Michel Baulac
  • Patent number: 6442421
    Abstract: A method for the detection of changes in dynamic properties of brain electrical activity is used to characterize and differentiate between physiological and pathological conditions, and to anticipate epileptic seizures. The detection of changes in dynamic properties of brain electrical activity is accomplished by constructing reference dynamics (Sref) of a normal state from an EEG, comparing the reference dynamics (Sref) with dynamics of a test segment (St), and computing the similarities over the entire EEG recordings by sliding the test segment (St) periodically.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: August 27, 2002
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Michel Le Van Quyen, Jacques Martinerie, Francisco Varela, Michel Baulac
  • Publication number: 20020095099
    Abstract: The invention concerns a device and a method for the detection of changes in dynamic properties of electrical brain activity to characterize and to differentiate between physiological and pathological conditions, or to anticipate epileptic seizures.
    Type: Application
    Filed: January 17, 2002
    Publication date: July 18, 2002
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFICQUE
    Inventors: Michel Le Van Quyen, Jacques Martinerie, Francisco Varela, Michel Baulac