Patents by Inventor Jacques Seguin

Jacques Seguin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11504234
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: November 22, 2022
    Assignee: BMEYE B.V.
    Inventor: Jacques Seguin
  • Publication number: 20220218210
    Abstract: Methods and systems are provided for diagnosis and/or treatment of microvascular dysfunction, such as microvascular obstruction (MVO) by injecting volumetric flows into a vessel using an infusion system to arrest or reverse native antegrade flow, such that an equipoise value of volumetric flow rate and corresponding pressure may be determined, which in turn enables calculation of MVO, absolute hydrodynamic resistance, fractional flow reserve, coronary flow reserve, and other physiologic parameters in real-time or near real time.
    Type: Application
    Filed: January 10, 2022
    Publication date: July 14, 2022
    Applicant: CorFlow Therapeutics AG
    Inventors: Robert S. SCHWARTZ, Martin T. ROTHMAN, Jacques SEGUIN
  • Publication number: 20200368020
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Application
    Filed: August 14, 2020
    Publication date: November 26, 2020
    Applicant: BMEYE B.V.
    Inventor: Jacques Seguin
  • Patent number: 10813752
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: October 27, 2020
    Assignee: BMEYE B.V.
    Inventor: Jacques Seguin
  • Patent number: 10743988
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: August 18, 2020
    Assignee: BMEYE B.V.
    Inventor: Jacques Seguin
  • Patent number: 10639154
    Abstract: An intervalvular implant for a mitral valve having a frame and a membrane covering the frame is provided. The frame includes an elongated base portion formed by two curved or chevron branches connected to two connection areas of the implant for connecting to the annulus of the mitral valve. The frame further includes a longitudinal hoop extending in a plane substantially perpendicular to the plane in which the elongated base portion extends. The membrane is flexible and extends from one branch to the other branch while passing around the longitudinal hoop. The membrane may be connected to the branches without being stretched between the branches and the hoop so that the membrane forms lateral portions on each side of the implant that are able to transition between an outwardly convex, concave shape, and an outwardly concave, recessed shape.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: May 5, 2020
    Inventor: Jacques Seguin
  • Patent number: 10406299
    Abstract: The invention relates to a system for the sequential intranasal administration of at least one active ingredient selected from a DR group having at least one side effect of respiratory depression and at least one active ingredient selected from an ADR group that counteracts the respiratory depression that may be induced by the active ingredients of the DR group. The invention also relates to a portable sequential intranasal administration device comprising an intranasal administration system according to the principles of the invention.
    Type: Grant
    Filed: February 8, 2016
    Date of Patent: September 10, 2019
    Assignee: Vapomed Limited
    Inventors: Jacques Seguin, Emad Sabry
  • Patent number: 10406300
    Abstract: Devices and methods for sequential aerosolized administration of pharmaceutical agents. A portable device may be used to administer an initial dose of an active formulation comprising at least one first pharmaceutical agent and a subsequent dose of an active formulation comprising at least one second pharmaceutical agent that may have the effect of countering, enhancing, or mitigating the first pharmaceutical agent.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: September 10, 2019
    Assignee: Vapomed Limited
    Inventors: Jacques Seguin, Emad Sabry
  • Patent number: 10383724
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: August 20, 2019
    Assignee: BMEYE B.V.
    Inventor: Jacques Seguin
  • Patent number: 10219901
    Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: March 5, 2019
    Assignee: MEDTRONIC CV LUXEMBOURG S.A.R.L.
    Inventors: Jacques Seguin, Georg Bortlein
  • Publication number: 20190029817
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Application
    Filed: September 28, 2018
    Publication date: January 31, 2019
    Inventor: Jacques Seguin
  • Publication number: 20190029816
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Application
    Filed: September 28, 2018
    Publication date: January 31, 2019
    Inventor: Jacques Seguin
  • Patent number: 9962258
    Abstract: A prosthetic heart valve comprises a collapsible and expandable support frame comprising a longitudinal axis. The frame comprises a first circumferential undulating structure defining an outflow end of the frame, and a second circumferential undulating structure spaced apart from the first circumferential undulating structure. The frame also comprises a plurality of struts longitudinally aligned with the longitudinal axis of the frame, and connecting the first circumferential undulating structure to the second circumferential undulating structure. Each strut of the plurality of struts comprises a first end terminating at a trough of the first circumferential undulating structure, and a second end terminating at a peak of the second circumferential undulating structure. The prosthetic heat valve also comprises a biological tissue valve coupled to the frame.
    Type: Grant
    Filed: February 11, 2014
    Date of Patent: May 8, 2018
    Assignee: MEDTRONIC CV LUXEMBOURG S.A.R.L.
    Inventors: Jacques Seguin, Georg Bortlein
  • Publication number: 20170273785
    Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable prosthesis frame. If desired, one or more expandable anchors may be used. The prosthesis frame, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the prosthesis frame may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia. The prosthesis frame is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.
    Type: Application
    Filed: April 6, 2017
    Publication date: September 28, 2017
    Inventors: Jacques Seguin, Georg Bortlein, Than Nguyen, Edward Pannek
  • Publication number: 20170224479
    Abstract: Systems and methods for mitral valve repair having a docking station and a valve implant. The docking station is an anchoring device having a helix structure. The valve implant is made of an expandable frame and a valve, and is radially expandable to a diameter that is at least the same as an expanded diameter of the anchoring device. The method of delivering the docking station and valve implant is performed by inserting the components through device delivery catheters.
    Type: Application
    Filed: April 21, 2017
    Publication date: August 10, 2017
    Inventor: Jacques Seguin
  • Publication number: 20170224477
    Abstract: This implant (1) has a frame (2) and a membrane (3) covering this frame; —the frame (2) has: —an elongated base portion (5) formed by two curved or chevron branches being connected to connecting areas (7) of the implant (1) for connecting to the annulus of the mitral valve (100); —a longitudinal hoop (8) extending in a plane substantially perpendicular to the plane in which extends said base portion; —the membrane (3) is flexible and extends from one branch to the other while passing near the hoop (8), this membrane being connected to said branches without being stretched between these branches and this hoop so that the two thereby formed lateral portions (3a) of the membrane (3) on both sides of the implant are able to adopt either a concave shape, outwardly convex, or a recessed shape, outwardly concave.
    Type: Application
    Filed: October 12, 2015
    Publication date: August 10, 2017
    Inventor: Jacques SEGUIN
  • Patent number: 9629716
    Abstract: Methods and apparatus are provided for repairing or replacing a defective cardiac valve including an anchor having a double helix configured to engage the cardiac valve leaflets of a diseased or defective cardiac valve, and a replacement valve body disposed in an expandable stent configured to be disposed within the anchor so that the anchor limits expansion of the expandable stent. The expandable stent of the replacement valve body may be self-expanding or mechanically expanded, e.g., using a balloon catheter or catheter-based mandrel and the valve body may be formed of animal tissue or a synthetic fabric.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: April 25, 2017
    Assignee: BMEYE B.V.
    Inventor: Jacques Seguin
  • Patent number: 9629720
    Abstract: Apparatus and methods for repairing a cardiac valve, e.g., a mitral valve, are provided. The apparatus may include an expandable frame defining a curved structure in the expanded deployed state and a membrane coupled to the expandable frame. The membrane may curve around a native leaflet, e.g., the posterior leaflet, in a first plane and curve around another leaflet, e.g., the anterior leaflet, in an orthogonal plane. The membrane may be adapted to be suspended in the flow path of the cardiac valve such a first surface of the membrane abuts the native leaflet during systole and a second surface of the membrane abuts the other native leaflet during systole, thereby reducing cardiac valve regurgitation.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: April 25, 2017
    Inventor: Jacques Seguin
  • Publication number: 20170100333
    Abstract: The invention relates to a system for the sequential intranasal administration of at least one active ingredient selected from a DR group having at least one side effect of respiratory depression and at least one active ingredient selected from an ADR group that counteracts the respiratory depression that may be induced by the active ingredients of the DR group. The invention also relates to a portable sequential intranasal administration device comprising an intranasal administration system according to the principles of the invention.
    Type: Application
    Filed: February 8, 2016
    Publication date: April 13, 2017
    Applicant: VAPOMED LIMITED
    Inventors: Jacques SEGUIN, Emad SABRY
  • Patent number: 9585754
    Abstract: Implants formed by a helically wound wire and methods of using same for the treatment of a mitral heart valve. According to the invention, it has dimensions such that it is able to be screwed into the wall of the annulus and/or into the cardiac wall adjoining the annulus such that a portion of the annulus and/or of the wall is located in the perimeter of the implant; and it comprises at least one first coil able, during said screwing of the implant, to insert itself into the wall while having a first dimension and at least one second coil having a second dimension, or adopting this second dimension after implantation, the second dimension being smaller than the first dimension such that the implant, once inserted, enables contraction of the wall portion located in the perimeter of the implant.
    Type: Grant
    Filed: December 17, 2015
    Date of Patent: March 7, 2017
    Assignee: Medtronic, Inc.
    Inventors: Jacques Seguin, Than Nguyen, Bruno Lecointe