Abstract: The present invention relates to halogenated salicylanilides, or pharmaceutically acceptable salts or esters thereof, for use in the treatment of an infection in a subject caused by Clostridium bacteria, particularly a C. difficile infection. The halogenated salicylanilides are expected to be useful in the treatment of C. difficile associated diseases including C. difficile associated diarrhoea and C. difficile associated colitis.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Gram positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: The protection device for providing protection against short-circuits upstream from an electrical power supply module having an inlet filter with at least one capacitor and an inductor and having a converter with components associated with a plurality of freewheel diodes includes at least one auxiliary winding and a dissipator element associated with the inlet filter, thereby making it possible to provide an inlet filter of small size without over dimensioning the freewheel diodes.

Abstract: The invention relates to a method for texturing a semiconductor substrate (1), comprising steps consisting in forming a plurality of cavities of random shapes, depths and distribution, in an etch mask (2), by means of non-homogeneous reactive-ion etching, forming a first rough random design, and etching the substrate using the etch mask, by means of reactive-ion etching, in such a way as to transfer the first rough random design into the substrate and to produce a second rough random design (200), comprising cavities (20) of random shapes, depths (d2r) and distribution, on the surface of the substrate.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Gram positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Gram positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

Abstract: Systems and methods for facilitating cloud-computing provisioning using deployment templates. A deployment management system receives a deployment template that includes a declarative portion specifying a plurality of resources to be deployed and an imperative portion specifying at least one procedure for adding, reconfiguring, or terminating a resource. The deployment management system generates an enumeration of a set of resources deployed prior to implementing a transition based on the deployment template, and generates a second enumeration of resources prospectively representative of a deployment conformant with the template subsequent to implementing the transition. The deployment management system identifies difference between the enumerations and generates a transition plan including a sequence of procedures for implementing the deployment template. In some implementations, an administrator can modify the transition plan.

Abstract: The invention relates to a method for texturing a semiconductor substrate (1), comprising steps consisting in forming a plurality of cavities of random shapes, depths and distribution, in an etch mask (2), by means of non-homogeneous reactive-ion etching, forming a first rough random design, and etching the substrate using the etch mask, by means of reactive-ion etching, in such a way as to transfer the first rough random design into the substrate and to produce a second rough random design (200), comprising cavities (20) of random shapes, depths (d2r) and distribution, on the surface of the substrate.

Abstract: Systems and methods for authorizing execution of actionable data by receiving a request to enable third-party use of the actionable data, the request authorized by an account with a first set of permissions, and recording the first set of permissions in association with the actionable data, receiving a request to execute the actionable data, the request authorized by an account with a second set of permissions, determining that a unified set of permissions inclusive of the first set of permissions and the second set of permissions is sufficient to authorize execution of the actionable data, and authorizing execution of the actionable data responsive to the determination. Presented as an example of actionable data is a deployment template for provisioning resources in a cloud computing environment. The disclosed systems and methods are equally applicable to other forms and contexts of actionable data.

Abstract: The protection device for providing protection against short-circuits upstream from an electrical power supply module having an inlet filter with at least one capacitor and an inductor and having a converter with components associated with a plurality of freewheel diodes includes at least one auxiliary winding and a dissipator element associated with the inlet filter, thereby making it possible to provide an inlet filter of small size without over dimensioning the freewheel diodes.

Abstract: A photoreflectance device for characterizing a rough surface includes a pump beam emitter to emit a pump beam; a probe beam emitter to emit a probe beam; a detector to detect the probe beam reflected by the surface; an integrating sphere to collect the probe beam reflected by the surface, the integrating sphere including: a first output connected to the detector, and disposed so as to receive a majority of the probe beam reflected by the surface; a second output arranged so as to receive a majority of the pump beam reflected by the surface.

Abstract: A method and system for facilitating management of cloud-based service instances, the system including one or more computing systems configured to communicate with at least one multi-tenant computing cloud, and configured to establish a cloud-based service instance hosted in the multi-tenant computing cloud and an access entity with permissions to access the established cloud-based service instance. The system can receive a request for the cloud-based service instance, the request authenticated as originating from a requestor; consult a set of access controls associated with the cloud-based service instance; determine, responsive to the consulting, if the request is allowable by the requestor; and enable, responsive to determining that the request is allowable by the requestor, the requestor to complete the request using a restricted access credential associated with the access entity.

Abstract: A photoreflectance device for characterizing a rough surface includes a pump beam emitter to emit a pump beam; a probe beam emitter to emit a probe beam; a detector to detect the probe beam reflected by the surface; an integrating sphere to collect the probe beam reflected by the surface, the integrating sphere including: a first output connected to the detector, and disposed so as to receive a majority of the probe beam reflected by the surface; a second output arranged so as to receive a majority of the pump beam reflected by the surface.

Abstract: A coiled electronic power component configured to be mounted on a base, the component including an axially extending magnetic core around which a plurality of turns are wound to form a magnetic coil, and at least one bracket for mounting on the base. The mounting bracket includes a first drain surface in thermal contact with the magnetic core and a second drain surface in thermal contact with the plurality of turns to drain calories from the magnetic core and from the plurality of turns to the base during operation of the component.

Abstract: The present invention is related to associating a machine or virtual machine instance with an access control right in a cloud-based computing environment. In one aspect, the present invention relates to an apparatus for or a method of associating a machine or virtual machine instance with an access control right in a cloud-based computing environment. In various embodiments, the apparatus is capable of, and the method includes, the following: receiving, in a cloud-based computing environment, a request to perform an action; using an identifier for the machine or virtual machine instance to determine that the received request was sent by, or on behalf of, the machine or virtual machine instance; and identifying an access control right associated with the machine or virtual machine instance making the request, to determine whether to perform the action on behalf of, or grant access by, the machine or virtual machine instance.

Abstract: A method and system for facilitating management of cloud-based service instances, the system comprising one or more computing systems configured to communicate with at least one multi-tenant computing cloud, and configured to establish a cloud-based service instance hosted in the multi-tenant computing cloud and an access entity with permissions to access the established cloud service instance. The system can receive a request for the cloud-based service instance, the request authenticated as originating from a requestor; consult a set of access controls associated with the cloud-based service instance; determine, responsive to the consulting, if the request is allowable by the requestor; and enable, responsive to determining that the request is allowable by the requestor, the requestor to complete the request using a restricted access credential associated with the access entity.

Abstract: A method and system for facilitating management of cloud-based service instances, the system including one or more computing systems configured to communicate with at least one multi-tenant computing cloud, and configured to establish a cloud-based service instance hosted in the multi-tenant computing cloud and an access entity with permissions to access the established cloud-based service instance. The system can receive a request for the cloud-based service instance, the request authenticated as originating from a requestor; consult a set of access controls associated with the cloud-based service instance; determine, responsive to the consulting, if the request is allowable by the requestor; and enable, responsive to determining that the request is allowable by the requestor, the requestor to complete the request using a restricted access credential associated with the access entity.

Abstract: The present invention is related to associating a machine or virtual machine instance with an access control right in a cloud-based computing environment. In one aspect, the present invention relates to an apparatus for or a method of associating a machine or virtual machine instance with an access control right in a cloud-based computing environment. In various embodiments, the apparatus is capable of, and the method includes, the following: receiving, in a cloud-based computing environment, a request to perform an action; using an identifier for the machine or virtual machine instance to determine that the received request was sent by, or on behalf of, the machine or virtual machine instance; and identifying an access control right associated with the machine or virtual machine instance making the request, to determine whether to perform the action on behalf of, or grant access by, the machine or virtual machine instance.

Abstract: The present invention is related to associating a machine or virtual machine instance with an access control right in a cloud-based computing environment. In one aspect, the present invention relates to an apparatus for or a method of associating a machine or virtual machine instance with an access control right in a cloud-based computing environment. In various embodiments, the apparatus is capable of, and the method includes, the following: receiving, in a cloud-based computing environment, a request to perform an action; using an identifier for the machine or virtual machine instance to determine that the received request was sent by, or on behalf of, the machine or virtual machine instance; and identifying an access control right associated with the machine or virtual machine instance making the request, to determine whether to perform the action on behalf of, or grant access by, the machine or virtual machine instance.