Patents by Inventor Jacqui Hoffman

Jacqui Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080090801
    Abstract: The present invention is directed to novel 4-methylpyridopyrimidinone compounds of Formula (I), and to salts thereof, their synthesis, and their use as inhibitors of phosphoinositide 3-kinase alpha (PI3-K?).
    Type: Application
    Filed: September 13, 2007
    Publication date: April 17, 2008
    Inventors: Hengmiao Cheng, Dilip Bhumralkar, Klaus Dress, Jacqui Hoffman, Mary Johnson, Robert Kania, Phuong Le, Mitchell Nambu, Mason Pairish, Michael Plewe, Khanh Tran
  • Publication number: 20050261290
    Abstract: The present invention relates to compounds with the formulas (I), (II), and (III), or a pharmaceutically acceptable salt thereof: wherein T is a (4 to 10)-membered heterocyclyl selected from the group consisting of and wherein R1, R2 and R3 are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formulas (I), (II), and (III) and methods of treating a condition that is mediated by the modulation of the 11-?-hsd-1 enzyme, the method comprising administering to a mammal an effective amount of a compound of formulas (I), (II), and (III).
    Type: Application
    Filed: May 4, 2005
    Publication date: November 24, 2005
    Inventors: Hengmiao Cheng, Stephan Cripps, Klaus Dress, Jacqui Hoffman, Buwen Huang, Stanley Kupchinsky, Phuong Le, Sajiv Nair, Timothy Parrott, Christopher Smith, Yong Wang, Yi Yang