Patents by Inventor Jadranka Koehn

Jadranka Koehn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ADENO-ASSOCIATED VIRUS PURIFICATION METHODS
    Publication number: 20220267796
    Abstract: Provided herein are methods of producing an adeno-associated virus (AAV) product and methods of purifying adeno-associated virus. AAV is loaded onto an affinity resin, wash steps are undertaken at room temperature, and AAV is eluted from the affinity resin at a lower temperature. Various buffers are disclosed for use in the wash steps and elution.
    Type: Application
    Filed: June 26, 2020
    Publication date: August 25, 2022
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Christian FIEDLER, Marcus SCHEINDEL, Meinhard HASSLACHER, Jadranka KOEHN
  • ADENO-ASSOCIATED VIRUS PURIFICATION METHODS
    Publication number: 20200332266
    Abstract: Provided herein are methods of producing an adeno-associated virus (AAV) product and methods of purifying adeno-associated virus. AAV is loaded onto an affinity resin, wash steps are undertaken, and AAV is eluted from the affinity resin. Various buffers are disclosed for use in the wash steps and elution.
    Type: Application
    Filed: December 27, 2018
    Publication date: October 22, 2020
    Applicants: BAXALTA INCORPORATED, BAXALTA GMBH
    Inventors: Christian FIEDLER, Meinhard HASSLACHER, Jadranka KOEHN
  • METHOD FOR PICKING A COLONY OF CELLS
    Publication number: 20180106713
    Abstract: The present invention relates to a method for picking a colony of cells and to producing a cell line from this colony, as well as to the cell line thus established and to use of this cell line in a method for producing a biological molecule or biological entity of interest.
    Type: Application
    Filed: May 30, 2016
    Publication date: April 19, 2018
    Applicants: Baxalta Incorporat, Baxalta GmbH
    Inventors: Jadranka KOEHN, Marianne NEURATH, Ernst BOEHM, Michael DOCKAL
  • Production of fully processed and functional factor X in a furin-secreting mammalian expression system
    Patent number: 9873892
    Abstract: Disclosed herein are methods for production of fully-processed mature Factor X in an expression system producing a controlled amount of furin between 50 U/mL and 300 U/mL of culture supernatant. Also disclosed are transformed cells, expression systems, and expression vectors for the expression of furin and Factor X.
    Type: Grant
    Filed: August 12, 2015
    Date of Patent: January 23, 2018
    Assignees: BAXALTA INCORPORATED, BAXALTA GMBH
    Inventors: Ernst Böhm, Franziska Horling, Jadranka Koehn, Michael Dockal
  • PRODUCTION OF FULLY PROCESSED AND FUNCTIONAL FACTOR X IN A FURIN-SECRETING MAMMALIAN EXPRESSION SYSTEM
    Publication number: 20160046957
    Abstract: Disclosed herein are methods for production of fully-processed mature Factor X in an expression system producing a controlled amount of furin between 50 U/mL and 300 U/mL of culture supernatant. Also disclosed are transformed cells, expression systems, and expression vectors for the expression of furin and Factor X.
    Type: Application
    Filed: August 12, 2015
    Publication date: February 18, 2016
    Inventors: Ernst Böhm, Franziska Horling, Jadranka Koehn, Michael Dockal