Patents by Inventor Jadwiga Bienkowska

Jadwiga Bienkowska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR CHARACTERIZATION OF MULTIPLE SCLEROSIS
    Publication number: 20170306402
    Abstract: Methods and systems to characterize multiple sclerosis (MS) in a subject, e.g., in a subject having a progressive form of MS are disclosed.
    Type: Application
    Filed: September 11, 2015
    Publication date: October 26, 2017
    Inventors: Raghavendra Hosur, Jadwiga Bienkowska
  • BIOMARKERS PREDICTIVE OF LUPUS PROGRESSION AND USES THEREOF
    Publication number: 20170269075
    Abstract: Methods, systems and kits to detect and/or quantify lupus and disease progression in a subject having, or at risk of having, lupus are disclosed.
    Type: Application
    Filed: May 11, 2015
    Publication date: September 21, 2017
    Inventors: Ann Marie RANGER, Jadwiga BIENKOWSKA, Carrie Greene WAGER, Laurence Saul MAGDER, Michelle PETRI
  • SYSTEMS AND METHODS FOR CHARACTERIZATION OF MULTIPLE SCLEROSIS
    Publication number: 20160040236
    Abstract: Methods and systems to characterize multiple sclerosis in a subject, e.g., in a subject a progressive form of MS are disclosed.
    Type: Application
    Filed: March 15, 2014
    Publication date: February 11, 2016
    Inventors: Raghavendra Hosur, Suzanne Szak, Jadwiga Bienkowska
  • LTBR BLOCKADE: METHODS FOR OPTIMIZING THERAPEUTIC RESPONSIVENESS OF PATIENTS
    Publication number: 20130216557
    Abstract: The invention provides compositions and methods for predicting therapeutic responsiveness of a subject having an autoimmune disorder to an agent that inhibits signaling via LT?R based on the level of expression of IFN or a marker thereof in the subject. The invention also provides methods of treating selected subjects with agents that inhibit or reduce signaling vial LT?R.
    Type: Application
    Filed: August 15, 2011
    Publication date: August 22, 2013
    Applicant: Biogen Idec MA Inc.
    Inventors: Jadwiga Bienkowska, Jeffrey L. Browning
  • Cell surface glycoprotein
    Patent number: 8124748
    Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: February 28, 2012
    Assignee: Ares Trading S.A.
    Inventors: Stephen Fitzgerald, Richard Fagan, Jadwiga Bienkowska, Christine Power, Melanie Yorke-Smith
  • BIOMARKERS FOR PREDICTING ANTI-TNF RESPONSIVENESS OR NON-RESPONSIVENESS
    Publication number: 20100303813
    Abstract: The present disclosure provides biomarkers that are predictive a subject's responsiveness or non-responsiveness to an anti-TNF therapy. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities (e.g., an anti-TNF therapy or a non-anti-TNF therapy) for a subject suffering from a disease such as an immune disorder.
    Type: Application
    Filed: June 6, 2008
    Publication date: December 2, 2010
    Applicants: Biogen Idec MA Inc., The Feinstein Institute for Medical Research
    Inventors: John P. Carulli, Peter K. Gregersen, Franak Batliwalla, Jadwiga Bienkowska, Chunyu Liu
  • Isolated INSP 163 protein
    Patent number: 7700724
    Abstract: This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a C1q-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: April 20, 2010
    Assignee: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke, Jadwiga Bienkowska
  • Cell Surface Glycoprotein
    Publication number: 20080124309
    Abstract: This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: August 11, 2005
    Publication date: May 29, 2008
    Applicant: Ares Trading S.A.
    Inventors: Stephen Fitzgerald, Richard Fagan, Jadwiga Bienkowska, Christine Power, Melanie Yorke-Smith
  • Alpha macroglobulin family member
    Publication number: 20070128600
    Abstract: This invention relates to a protein, termed INSP097, herein identified as a member of the alpha macroglobulin family, in particular as an alpha-2-macroglobulin-like proteinase inhibitor, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: November 7, 2003
    Publication date: June 7, 2007
    Inventors: Richard Fagan, Christopher Phelps, Tania Rodrigues, Christine Power, Jadwiga Bienkowska
  • C1q related protein
    Publication number: 20070072260
    Abstract: This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a C1q-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: October 27, 2004
    Publication date: March 29, 2007
    Inventors: Stephen Fitzgerald, Richard Fagan, Christine Power, Melanie Yorke, Jadwiga Bienkowska
  • Novel il-8-like polypeptides
    Publication number: 20070067858
    Abstract: The present invention discloses open reading frames (ORFs) in human genome encoding for novel IL-8-like/TMEM9 polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
    Type: Application
    Filed: May 27, 2004
    Publication date: March 22, 2007
    Inventors: Gregg Mcallister, Regina Gorski, Jadwiga Bienkowska
  • Alpha macroglobulin protein family members
    Publication number: 20070021588
    Abstract: This invention relates to two proteins, termed INSP087, herein identified as members of the alpha macroglobulin family, in particular as alpha-2-macroglobulin-like proteinase inhibitors, and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention, and treatment of disease.
    Type: Application
    Filed: October 16, 2003
    Publication date: January 25, 2007
    Inventors: Richard Fagan, Christopher Phelps, Tania Rodrigues, Christine Power, Jadwiga Bienkowska
  • Novel fibrillin-like polypeptides
    Publication number: 20060248603
    Abstract: The present invention discloses open reading frames (ORFS) in human genome encoding for novel fibrillin-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
    Type: Application
    Filed: December 22, 2003
    Publication date: November 2, 2006
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Gregg McAllister, Jadwiga Bienkowska
  • Novel fibulin-like polypeptides
    Publication number: 20060228709
    Abstract: The present invention discloses open reading frames (ORFs) in human genome encoding for novel fibulin-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
    Type: Application
    Filed: December 10, 2003
    Publication date: October 12, 2006
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Jadwiga Bienkowska, Gregg Mcallister
  • Novel preadipocyte factor-1-like polypeptides
    Publication number: 20060155117
    Abstract: The present invention discloses open reading frames (ORFs) in human genome encoding for novel Preadipocyte factor-1-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
    Type: Application
    Filed: December 23, 2003
    Publication date: July 13, 2006
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Jadwiga Bienkowska, Gregg Mcallister
  • Novel mucin-like polypeptides
    Publication number: 20060150262
    Abstract: The present invention discloses open reading frame (ORFs) in human genome encoding for novel mucin-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: February 4, 2004
    Publication date: July 6, 2006
    Inventors: Jadwiga Bienkowska, Gregg McAllister
  • Novel notch-like polypeptides
    Publication number: 20060141468
    Abstract: The present invention discloses open reading frames (ORFs) in human genome encoding for novel notch-like polypeptides, and reagents related thereto including variants, mutants and fragments of said polypeptides, as well as ligands and antagonists directed against them. The invention provides methods for identifying and making these molecules, for preparing pharmaceutical compositions containing them, and for using them in the diagnosis, prevention and treatment of diseases.
    Type: Application
    Filed: December 9, 2003
    Publication date: June 29, 2006
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Jadwiga Bienkowska, Gregg Macallister