Patents by Inventor Jae Hong Kweon

Jae Hong Kweon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE FORM OF HETEROCYCLIC COMPOUND AS PROTEIN KINASE INHIBITOR
    Publication number: 20240051957
    Abstract: The present invention relates to a crystalline form of the heterocyclic compound N-(4-(1-(2-cyanoacetyl)-3-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-pyrrolo[2,3-b]pyridin-6-yl)cyclopropanecarboxamide as a protein kinase inhibitor.
    Type: Application
    Filed: March 16, 2022
    Publication date: February 15, 2024
    Inventors: Young Ju Kim, Jun Kim, Hanna Kim, Jae Hong Kweon, Ye-Lim Lee, Do Seok Hwang
  • Intermediates for optically active piperidine derivatives and preparation methods thereof
    Patent number: 11780810
    Abstract: A preparation method according to the present invention makes it possible to industrially produce large amounts of highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield by use of commercially available reagents and solvents. In addition, the use of novel intermediates according to the present invention makes it possible to produce highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield.
    Type: Grant
    Filed: January 7, 2022
    Date of Patent: October 10, 2023
    Inventors: Jae Hong Kweon, Eun Sun Kim, Hyuk Woo Lee, Dong Hyun Ko, Chae Young Ryu, Kwang Do Choi, SeungPyeong Heo
  • Intermediates for Optically Active Piperidine Derivatives and Preparation Methods Thereof
    Publication number: 20220127230
    Abstract: A preparation method according to the present invention makes it possible to industrially produce large amounts of highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield by use of commercially available reagents and solvents. In addition, the use of novel intermediates according to the present invention makes it possible to produce highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield.
    Type: Application
    Filed: January 7, 2022
    Publication date: April 28, 2022
    Inventors: Jae Hong Kweon, Eun Sun Kim, Hyuk Woo Lee, Dong Hyun Ko, Chae Young Ryu, Kwang Do Choi, SeungPyeong Heo
  • Intermediates for optically active piperidine derivatives and preparation methods thereof
    Patent number: 11254641
    Abstract: A preparation method according to the present invention makes it possible to industrially produce large amounts of highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield by use of commercially available reagents and solvents. In addition, the use of novel intermediates according to the present invention makes it possible to produce highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: February 22, 2022
    Assignee: HK inno.N Corporation
    Inventors: Jae Hong Kweon, Eun Sun Kim, Hyuk Woo Lee, Dong Hyun Ko, Chae Young Ryu, Kwang Do Choi, SeungPyeong Heo
  • Intermediates for Optically Active Piperidine Derivatives and Preparation Methods Thereof
    Publication number: 20210107873
    Abstract: A preparation method according to the present invention makes it possible to industrially produce large amounts of highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield by use of commercially available reagents and solvents. In addition, the use of novel intermediates according to the present invention makes it possible to produce highly pure optically active tert-butyl 3-methyl-4-oxopiperidine-1-carboxylate in high yield.
    Type: Application
    Filed: December 7, 2018
    Publication date: April 15, 2021
    Inventors: Jae Hong Kweon, Eun Sun Kim, Hyuk Woo Lee, Dong Hyun Ko, Chae Young Ryu, Kwang Do Choi, SeungPyeong Heo
  • Crystalline form of a benzimidazole derivative and a preparation method thereof
    Patent number: 9908870
    Abstract: The present invention relates to a novel crystalline form of a benzimidazole derivative and a preparation method thereof. The novel crystalline form according to the present invention is hardly changed chemically and/or physically under a long-term photo-stressed condition, has a low hygroscopicity, and has an extremely low static-electricity-inducing capability, thus being advantageous for formulation, and due to the excellent stability of the crystal form itself, it is very useful for long-term storage of the compound.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: March 6, 2018
    Assignee: CJ HEALTHCARE CORPORATION
    Inventors: Young Ju Kim, Eun Sun Kim, Ji Yun Lee, Hyuk Woo Lee, Jae Hong Kweon, Sung Ah Lee, Kwang Do Choi, Dong Hyun Ko, Seung Pyeong Heo
  • A NOVEL CRYSTALLINE FORM OF A BENZIMIDAZOLE DERIVATIVE AND A PREPARATION METHOD THEREOF
    Publication number: 20180009791
    Abstract: The present invention relates to a novel crystalline form of a benzimidazole derivative and a preparation method thereof. The novel crystalline form according to the present invention is hardly changed chemically and/or physically under a long-term photo-stressed condition, has a low hygroscopicity, and has an extremely low static-electricity-inducing capability, thus being advantageous for formulation, and due to the excellent stability of the crystal form itself, it is very useful for long-term storage of the compound.
    Type: Application
    Filed: November 18, 2015
    Publication date: January 11, 2018
    Inventors: Young Ju KIM, Eun Sun KIM, Ji Yun LEE, Hyuk Woo LEE, Jae Hong KWEON, Sung Ah LEE, Kwang Do CHOI, Dong Hyun KO, Seung Pyeong HEO
  • Method for preparation of benzimidazole derivatives
    Patent number: 9493425
    Abstract: The present invention provides a method for preparing a compound with a benzimidazole structure with an excellent yield using a low-cost starting material, not requiring an additional separation process, or not using a dangerous reagent during the manufacturing process. Furthermore, the present invention also provides an intermediate and a final product produced by the preparing method.
    Type: Grant
    Filed: July 4, 2014
    Date of Patent: November 15, 2016
    Assignee: CJ HEALTHCARE CORPORATION
    Inventors: Jae Hong Kweon, Eun Sun Kim, Seog Beom Song, Sung Ah Lee, Ji Yun Lee, Kwang Do Choi, Young Joon Park
  • METHOD FOR PREPARATION OF BENZIMIDAZOLE DERIVATIVES
    Publication number: 20160159747
    Abstract: The present invention provides a method for preparing a compound with a benzimidazole structure with an excellent yield using a low-cost starting material, not requiring an additional separation process, or not using a dangerous reagent during the manufacturing process. Furthermore, the present invention also provides an intermediate and a final product produced by the preparing method.
    Type: Application
    Filed: July 4, 2014
    Publication date: June 9, 2016
    Inventors: Jae Hong Kweon, Eun Sn Kim, Seog Beom Song, Sung Ah Lee, Ji Yun Lee, Kwang Do Choi, Young Joon Park
  • THIAZOLIDINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF
    Publication number: 20100048570
    Abstract: The present invention relates to novel 2-carbonyl-3-acyl-1,3-thiazolidines having a ?-amino group on the acyl chain, in free, prodrug form or pharmaceutically acceptable salt thereof, including their enantiomers, diastereomers and racemates, as efficient inhibitors against DPP-IV. The invention further relates to the pharmaceutical compositions comprising the disclosed compounds. The present invention also relates to methods for preparing the disclosed compounds and for treating DPP-IV-mediated diseases.
    Type: Application
    Filed: January 16, 2008
    Publication date: February 25, 2010
    Applicants: Kainos Medicine, Inc, Korea Research Institute of Chemical Technology, Yungjin Pharmaceutical Company, Ltd
    Inventors: Sung Soo Kim, Jin Hee Ahn, Hyae Gyeong Cheon, Sang Dal Rhee, Nam Sook Kang, Ki Young Kim, Seung Kyu Kang, Won Hoon Jung, Sung Gyu Kim, Sun Young Kim, Jae Hong Kweon, Sang Kwon Sohn, Min Ki Shin, Ni Na Ha