Abstract: There is provided a transnasal anticonvulsive pharmaceutical composition including a poorly soluble anticonvulsant. The anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether and fatty acid ester, wherein the fatty acid ester is selected from the group consisting of caprylocaproyl polyoxylglyceride, isopropyl palmitate, oleoyl polyoxylglyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate and polysorbate 20. Also, the anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether, fatty acid ester, methylpyrrolidone, water and alcohol. Therefore, the transnasal anticonvulsive pharmaceutical composition may be useful to highly enhance the bioavailability of the poorly soluble anticonvulsant.

Abstract: There is provided a transnasal anticonvulsive pharmaceutical composition including a poorly soluble anticonvulsant. The anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether and fatty acid ester, wherein the fatty acid ester is selected from the group consisting of caprylocaproyl polyoxylglyceride, isopropyl palmitate, oleoyl polyoxylglyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate, and polysorbate 20. Also, the anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether, fatty acid ester, methylpyrrolidone, water and alcohol. Therefore, the transnasal anticonvulsive pharmaceutical composition may be useful to highly enhance the bioavailability of the poorly soluble anticonvulsant.

Abstract: Provided are a novel isoprene synthase derived from sweet potato and a method of preparing isoprene using the same, and more specifically, a novel isoprene synthase derived from sweet potato, a gene encoding the isoprene synthase, a host cell transformed with the gene, and a method of preparing isoprene using the same. The isoprene synthase of the present invention may have higher isoprene productivity as compared to isoprene synthases known in the related art to thereby be effectively used in isoprene biosynthesis and preparation of an isoprene polymer using the same.

Abstract: The present invention generally relates to intranasal pharmaceutical compositions comprising a benzodiazepine and methods of use thereof that can provide a therapeutic effect without a decrease in blood pressure and/or pulse after administration of the pharmaceutical composition.

Abstract: An apparatus and method for adjusting an operating frequency of a multi-band antenna and a system supporting the same in a wireless communication system are provided, in which a plurality of shorting pins spaced from a radiation patch by difference distances, and a switch connects one of the shorting pins to the radiation patch.

Abstract: An antenna device of a mobile communication terminal is provided, the device including at least one radiation pattern and at least one magneto dielectric module or dielectric module installed in a selected position on the radiation pattern to tune one or more resonance frequencies of the radiation pattern according to resonance frequencies required for the terminal. The radiation pattern is selected from among one or more radiation patterns fabricated according to a usable frequency band. The one or more radiation patterns each include one or more resonance frequencies. The magneto dielectric module is selected from among one or more magneto dielectric modules fabricated for controlling the one or more resonance frequencies of the one or more radiation patterns. The dielectric module is selected from among one or more dielectric modules fabricated for controlling the one or more resonance frequencies of the one or more radiation patterns.

Abstract: The present invention generally relates to intranasal pharmaceutical compositions comprising a benzodiazepine and methods of use thereof that can provide a therapeutic effect without a decrease in blood pressure and/or pulse after administration of the pharmaceutical composition.

Abstract: There is provided a transnasal anticonvulsive pharmaceutical composition including a poorly soluble anticonvulsant. The anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether and fatty acid ester, wherein the fatty acid ester is selected from the group consisting of caprylocaproyl polyoxylglyceride, isopropyl palmitate, oleoyl polyoxylglyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate, and polysorbate 20. Also, the anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether, fatty acid ester, methylpyrrolidone, water and alcohol. Therefore, the transnasal anticonvulsive pharmaceutical composition may be useful to highly enhance the bioavailability of the poorly soluble anticonvulsant.

Abstract: An apparatus for multiple antennas having a low coupling coefficient in a wide frequency bandwidth in a wireless communication system is provided. To obtain the low coupling coefficient in the wide frequency bandwidth by minimizing interference between antennas which are close to each other, without an additional device, in the wireless communication system, the apparatus includes a transceiver and a line for decreasing a coupling coefficient. The transmitter includes a first antenna and a second antenna for transmitting and receiving signals over a radio channel and the line is indirectly connected the first antenna and the second antenna using a physically disconnected line.

Abstract: There is provided a transnasal anticonvulsive pharmaceutical composition including a poorly soluble anticonvulsant. The anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether and fatty acid ester, wherein the fatty acid ester is selected from the group consisting of caprylocaproyl polyoxylglyceride, isopropyl palmitate, oleoyl polyoxylglyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate, and polysorbate 20. Also, the anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether, fatty acid ester, methylpyrrolidone, water and alcohol. Therefore, the transnasal anticonvulsive pharmaceutical composition may be useful to highly enhance the bioavailability of the poorly soluble anticonvulsant.

Abstract: A method for fabricating an antenna device of a mobile communication terminal, the method including selecting radiation patterns according to a usable frequency band, selecting and fabricating magneto dielectric modules for adjusting resonance frequencies of the selected radiation patterns, selecting and fabricating dielectric modules for adjusting resonance frequency of the selected radiation patterns, selecting and fabricating a radiation pattern having a number of resonance frequencies required for the terminal from among the radiation patterns selected in the pattern selection step, and selecting at least one of the magneto dielectric modules and the dielectric modules and installing it in the radiation pattern to tune a resonance frequency of the radiation pattern to the resonance frequency required for the terminal.

Abstract: The present invention generally relates to intranasal pharmaceutical compositions comprising a benzodiazepine and methods of use thereof that can provide a therapeutic effect without a decrease in blood pressure and/or pulse after administration of the pharmaceutical composition.

Abstract: There is provided a transnasal anticonvulsive pharmaceutical composition including a poorly soluble anti-convulsant. The anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether and fatty acid ester, wherein the fatty acid ester is selected from the group consisting of caprylocaproyl polyoxylglyceride, isopropyl palmitate, oleoyl polyoxylglyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate, and polysorbate 20. Also, the anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether, fatty acid ester, methylpyrrolidone, water and alcohol. Therefore, the transnasal anticonvulsive pharmaceutical composition may be useful to highly enhance the bioavailability of the poorly soluble anticonvulsant.

Abstract: An apparatus and method for adjusting an operating frequency of a multi-band antenna and a system supporting the same in a wireless communication system are provided, in which a plurality of shorting pins spaced from a radiation patch by difference distances, and a switch connects one of the shorting pins to the radiation patch.

Abstract: A Multiple-Input Multiple-Output (MIMO) antenna system with multiple antennas is provided. The MIMO antenna system includes a number of conductive elements, and a number of band stop devices. The conductive elements are spaced apart from each other and operate in corresponding resonant frequency bands respectively when they receive electric power. When the conductive elements are operated, the band stop devices block interference between the conductive elements in the resonant frequency bands, and isolate the conductive elements from each other. The band stop devices are located between adjacently separate conductive elements and connect the conductive elements to each other. The MIMO antenna system can stop interference between the conductive elements via the band stop devices, thereby increasing the operational efficiency of the conductive elements.

Abstract: An apparatus for multiple antennas having a low coupling coefficient in a wide frequency bandwidth in a wireless communication system is provided. To obtain the low coupling coefficient in the wide frequency bandwidth by minimizing interference between antennas which are close to each other, without an additional device, in the wireless communication system, the apparatus includes a transceiver and a line for decreasing a coupling coefficient. The transmitter includes a first antenna and a second antenna for transmitting and receiving signals over a radio channel and the line is indirectly connected the first antenna and the second antenna using a physically disconnected line.

Abstract: There is provided a transnasal anticonvulsive pharmaceutical composition including a poorly soluble anti-convulsant. The anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether and fatty acid ester, wherein the fatty acid ester is selected from the group consisting of caprylocaproyl polyoxylglyceride, isopropyl palmitate, oleoyl polyoxylglyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate, and polysorbate 20. Also, the anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether, fatty acid ester, methylpyrrolidone, water and alcohol. Therefore, the transnasal anticonvulsive pharmaceutical composition may be useful to highly enhance the bioavailability of the poorly soluble anticonvulsant.

Abstract: A method for fabricating an antenna device of a mobile communication terminal, the method including selecting radiation patterns according to a usable frequency band, selecting and fabricating magneto dielectric modules for adjusting resonance frequencies of the selected radiation patterns, selecting and fabricating dielectric modules for adjusting resonance frequency of the selected radiation patterns, selecting and fabricating a radiation pattern having a number of resonance frequencies required for the terminal from among the radiation patterns selected in the pattern selection step, and selecting at least one of the magneto dielectric modules and the dielectric modules and installing it in the radiation pattern to tune a resonance frequency of the radiation pattern to the resonance frequency required for the terminal.

Abstract: Disclosed herein is a transnasal anticonvulsive pharmaceutical composition comprising diazepam as an active ingredient, water, a fatty acid ester, diethylene glycol monoethyl ether, ethanol and sodium glycocholate, wherein the weight of the fatty acid ester is at least 2-fold higher than that of water and is at least 2-fold higher than that of ethanol. The anticonvulsive pharmaceutical composition for transmucosal delivery of diazepam according to the present invention includes a minimized content of water and ethanol, a fatty acid ester as a main ingredient and no use of a polar solvent, e.g. glycol, and, exhibits improved diazepam solubility and transmucosal permeability due to using a small amount of water and ethanol. The present invention also includes treatment of convulsions by transnasally administering to a patient in need thereof a therapeutically effective amount of the disclosed compositions.

Abstract: There is disclosed a transdermal composition comprising from about 0.1 to 25% by weight of a piroxicam-inorganic material complex composed of a swellable clay and piroxicam intercalated between layers thereof, from about 50 to 80% by weight of an adhesive polymeric material, and from about 0.1 to 25% by weight of an absorption enhancer. There is further disclosed a transdermal patch system comprising the subject transdermal composition. In the transdermal composition, piroxicam is dispersed on a molecular level between layers of a clay material. As a result, the dispersability, stability and solubility of the piroxicam are improved, the recrystallization of the piroxicam is prevented, and excellent absorption properties and skin permeability of the piroxicam are achieved. Therefore, excellent anti-inflammatory and analgesic effects are exhibited, little or no skin irritation is caused, thereby preventing occurrence of side effects, and the active ingredient is continuously administered by a transdermal route.