Patents by Inventor Jae-Il Ahn

Jae-Il Ahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crosslinked hydrogels and related method of preparation
    Patent number: 9987225
    Abstract: The present invention provides a method of manufacturing a hydrogel comprising the step of crosslinking a biopolymer using a carbodiimide crosslinker of Formula I wherein at least one of R1 and R2 is a functional group that is a bulky organic functional group. R1 and R2 can each independently be an optionally substituted saturated or unsaturated functional group selected from the group consisting of an alkyl, a cycloalkyl, a heterocyclic, and an aryl. The bulky organic functional group will slow down the crosslinking reaction of carbodiimide due to the steric effects and/or electronic effects, in comparison to a crosslinking reaction using EDC. Also provided are the hydrogels and ophthalmic devices prepared using the method of the invention and uses thereof.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: June 5, 2018
    Assignee: Ottawa Hospital Research Institute
    Inventors: May Griffith, Fengfu Li, Jae-Il Ahn
  • Crosslinked Hydrogels and Related Method of Preparation
    Publication number: 20120321585
    Abstract: The present invention provides a method of manufacturing a hydrogel comprising the step of crosslinking a biopolymer using a carbodiimide crosslinker of Formula I wherein at least one of R1 and R2 is a functional group that is a bulky organic functional group. R1 and R2 can each independently be an optionally substituted saturated or unsaturated functional group selected from the group consisting of an alkyl, a cycloalkyl, a heterocyclic, and an aryl. The bulky organic functional group will slow down the crosslinking reaction of carbodiimide due to the steric effects and/or electronic effects, in comparison to a crosslinking reaction using EDC. Also provided are the hydrogels and ophthalmic devices prepared using the method of the invention and uses thereof.
    Type: Application
    Filed: September 29, 2010
    Publication date: December 20, 2012
    Applicants: UNIVERSITY OF OTTAWA, OTTAWA HOSPITAL RESEARCH INSTITUTE
    Inventors: May Griffith, Fengfu Li, Jae-Il Ahn