Patents by Inventor Jae Keith Joung

Jae Keith Joung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Transcription activator-like effector (tale) - lysine-specific demethylase 1 (LSD1) fusion proteins
    Patent number: 11891631
    Abstract: Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: February 6, 2024
    Assignee: The General Hospital Corporation
    Inventors: Jae Keith Joung, Eric M. Mendenhall, Bradley E. Bernstein, Deepak Reyon
  • TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) - LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) FUSION PROTEINS
    Publication number: 20190359951
    Abstract: Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof.
    Type: Application
    Filed: April 5, 2019
    Publication date: November 28, 2019
    Inventors: Jae Keith Joung, Eric M. Mendenhall, Bradley E. Bernstein, Deepak Reyon
  • TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR (TALE) - LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) FUSION PROTEINS
    Publication number: 20150267176
    Abstract: Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array (TALE) or zinc finger array, and a catalytic domain comprising a sequence that catalyzes histone demethylation, and methods of use thereof.
    Type: Application
    Filed: October 11, 2013
    Publication date: September 24, 2015
    Inventors: Jae Keith Joung, Eric M. Mendenhall, Bradley E. Bernstein, Deepak Reyon
  • ZINC FINGER NUCLEASE FOR THE CFTR GENE AND METHODS OF USE THEREOF
    Publication number: 20150093802
    Abstract: The present invention provides new zinc finger proteins and zinc finger nuclease (ZFNs) that find particular using in repairing the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
    Type: Application
    Filed: September 30, 2014
    Publication date: April 2, 2015
    Applicants: UNIVERSITY OF IOWA RESEARCH FOUNDATION, THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL
    Inventors: Paul MCCRAY, Morgan MAEDER, Jae Keith JOUNG
  • Zinc finger nuclease for the CFTR gene and methods of use thereof
    Patent number: 8846578
    Abstract: The present invention provides new zinc finger proteins and zinc finger nuclease (ZFNs) that find particular using in repairing the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: September 30, 2014
    Assignees: The General Hospital Corporation, University of Iowa Research Foundation
    Inventors: Paul McCray, Morgan Maeder, Jae Keith Joung
  • ZINC FINGER NUCLEASE FOR THE CFTR GENE AND METHODS OF USE THEREOF
    Publication number: 20110086015
    Abstract: The present invention provides new zinc finger proteins and zinc finger nuclease (ZFNs) that find particular using in repairing the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 14, 2011
    Inventors: Paul McCray, Morgan Maeder, Jae Keith Joung
  • Bacterial counterselectable hybrid systems
    Patent number: 7504216
    Abstract: The present application relates to the hybrid selection methods in prokaryotes using counterselectable reporter genes.
    Type: Grant
    Filed: February 2, 2005
    Date of Patent: March 17, 2009
    Assignee: University of Massachusetts
    Inventors: Scot Andrew Wolfe, Xiangdong Meng, Jae Keith Joung