Abstract: Disclosed is a novel dicarboxylic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Abstract: Disclosed are novel inorganic acid salts of sibutramine, which have good physicochemical properties, and crystalline forms thereof. Also disclosed are pharmaceutical compositions comprising the compounds as effective ingredients, methods of preparing the compounds, and the use of the compounds.

Abstract: The method of activating a vehicle fuel cell for ensuring maximum performance, improves performance of a polymer electrolyte membrane fuel cell, reduces a hydrogen usage, and has stable performance after manufactured. The method includes: placing a fuel cell in an activation device so as to be activated; changing a humidification state of a humidifier which supplies vapor to the fuel cell and a state of a cooling water; supplying a reactant gas to the fuel cell and maintaining a no-load state; maintaining a load state while changing a flow rate of the vapor and gas supplied to the fuel cell; changing the sate of the fuel cell to the no-load state, and re-supplying the reactant gas to the fuel cell; and comparing data measured when the fuel cell operates in the no-load state and data measured when the fuel cell operates in the load state respectively with a reference value.

Abstract: Provided is a sustained-release formulation: (a) a sustained-release core including an active ingredient and a polymer having erosion and swelling property in mammalian intestinal secretions, (b) an enteric film coating layer coated on the sustained-release core, and (c) an active ingredient-containing film coating layer coated on the enteric film coating layer and including the active ingredient and hydrophilic polymer for film coating.

Abstract: A microemulsion preconcentrate is provided, which comprises an active component, an oil, a surfactant, and a hydrophilic solvent selected from the group consisting of propylene glycol diacetate, propylene glycol monoacetate, and salts of the forgoing materials.