Abstract: The present disclosure relates to an isolated anti-FcRN antibody, which is an antibody binding to FcRN (stands for neonatal Fc receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmunre diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases.

Abstract: A pouch type lithium secondary battery includes a crude cell equipped with electrode leads and electrode tabs, a battery case for sealing the crude cell, and insulating materials provided on an inner surface of the battery case in which the electrode leads and the electrode tabs are disposed. In a method of fabricating a pouch type lithium secondary battery comprising a crude cell equipped with electrode leads and electrode tabs, and a battery case for sealing the crude cell, the battery case is comprised of a first receiving portion for receiving the crude cell and a second receiving portion for receiving the electrode leads. The method includes the steps of processing insulating materials on an inner surface of the second receiving portion, inserting the crude cell into the battery case, and sealing the battery case.

Abstract: The present invention discloses a crude cell for a large secondary battery comprising unit cells alternately stacked in the fold/fold type or a crude cell for a large secondary battery comprising unit cells wound and stacked in the jelly roll type, each unit cell having an anode, a cathode and a separator, in which a polymer film is inserted in the crude cell to support the crude cell. According to the present invention, it is possible to prevent structural distortion caused by external impact and self reaction of the crude cell by firmly supporting the crude cell. Consequently, it is possible to prevent short of the anode and the cathode in the crude cell by electrical connection and to improve interfacial properties of the anode, the cathode and the separator.