Patents by Inventor Jae Kyoung Pak

Jae Kyoung Pak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N and/or N derivatized, metal and organic protected L-histidine for coupling to biomolecules for highly efficient labeling with [M(OH)(CO)] by coordination
    Patent number: 8512675
    Abstract: The present invention relates to novel histidine derivates that can be used for the labeling of biomolecules with radioactive metal tricarbonyls. The new derivatives have a histidine that is derivatized at the N? and at least protected at the N? and optionally at the N?; or derivatized at the N? and at least protected at the N? and optionally at the N?; or derivatized at the N? and N? and at least protected at the N? and optionally at the N?; or derivatized at the N?; or derivatized at the N?; or derivatized at the N? and N?; or at least protected at the N? and optionally at the N?.
    Type: Grant
    Filed: April 29, 2004
    Date of Patent: August 20, 2013
    Assignee: Mallinckrodt LLC
    Inventors: Roger Alberto, Jae Kyoung Pak
  • Process for the preparation of imidazopyridines
    Patent number: 6841679
    Abstract: A compound of the general formula (1), in which: Y denotes hydrogen, a halogen or a C1-4 alkyl group; X1 and X2 denote, independently of each other, hydrogen, a halogen, a C1-4 alkoxy, C1-6 alkyl, CF3, CH3S CH3SO2 or NO2 group; and R1 and R2 denote independently of each other, hydrogen or a C1-5 alkyl group, with the proviso that R1 and R2 do not both denote hydrogen, or a salt thereof, and is prepared by a multi-step process, the last step of which comprises reducing a compound of the general formula (6), in which Y, X1, X2, R1 and R2 are as defined above with an appropriate reducing agent, such as Zn, and, if desired, converting the compound of formula (1) thus obtained, into a salt. The products of this process are known to have useful pharmacological properties, e.g. as anxiolytics.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: January 11, 2005
    Assignee: Cilag AG
    Inventors: Heidedore Hisabeth Rey-Papina, Armin Rossler, Giusep Derungs, Jae Kyoung Pak, Max Rey
  • Process for the preparation of imidazopyridines
    Publication number: 20040072861
    Abstract: A compound of general formula (1), in which: Y denotes hydrogen, a halogen or a C1-4 alkyl group X1 and X2 denote, independently of each other, hydrogen, a halogen or a C1-4 alkoxy, C1-6 alkyl, CF3, CH3S CH3SO2 or NO2 group and R1 and R2 denote independently of each other, hydrogen or a C1-5 alkyl group, with the proviso that R1 and R2 do not both denote hydrogen, or a salt thereof is prepared by a multi-step process, the last step of which comprises reducing a compound of the general formula (6), in which Y, X1, X2, R1 and R2 are as defined above with an appropriate reducing agent, such as Zn, and, if desired, converting the compound of formula (1) thus obtained, into a salt. The products of this process are known to have useful pharmacological properties, e.g. as anxiolytics.
    Type: Application
    Filed: November 24, 2003
    Publication date: April 15, 2004
    Inventors: Max Rey, H. J. Rey-Papina, Armin Rossler, Giusep Derungs, Jae Kyoung Pak