Abstract: Disclosed are an oral film and stick jelly containing glutathione and a milk thistle extract. Provided are an oral disintegrating film, an oral mucosal adhesive film, and a stick jelly that contain glutathione, a milk thistle extract, or the like as an active ingredient, and thus are highly efficacious in improving absorption in the oral mucosa, antioxidant activity, and anti-inflammatory activity, strengthening immunity, and enhancing liver function of humans and companion animals.

Abstract: The present invention provides a pharmaceutical composition for prevention or treatment of a stress disease and depression, the pharmaceutical composition be safely useable without toxicity and side effects by using an extract of leaves of Vaccinium bracteatum Thunb., which is natural resource of Korea, so that the reduction of manufacturing and production costs and the import substitution and export effects can be expected through the replacement of a raw material for preparation with a plant inhabiting in nature.

Abstract: A dual set-up zoom actuator includes a first carrier having a first lens and movable along an optical axis, a second carrier having a second lens and being capable of moving anterior or posterior to the first carrier along the optical axis, a housing enclosing the first and second carriers, a first coil unit equipped to the housing and having n, which is a natural number not less than two, first coils disposed anterior or posterior along the optical axis, a second coil unit equipped to the housing at a location different than the first coil unit and having n+1 second coils disposed anterior or posterior along the optical axis, a first magnet having n+1 magnetic poles facing the first coil unit and mounted on the first carrier, and a second magnet having n magnetic poles facing the second coil unit and mounted on the second carrier.

Abstract: Apparatuses for camera calibration using a light source are provided, one of apparatus comprises, a n-light sources (n is 3 or more) which can be mounted on the camera, an actual coordinate computation processing unit which irradiates light to an image pickup surface being captured by the camera through the n-light sources to capture an image of an n-sided polygon made up of n-light spots formed on the image pickup surface, and analyses a degree of distortion on the n-sided screen to obtain n or more coordinate pairs obtained by matching the coordinates on the screen and the coordinates on an actual space and a calibration computation processing unit which receives the n or more coordinate pairs as input to convert a two-dimensional coordinate on the screen into a three-dimensional coordinate on the actual space.

Abstract: Inhibitors of AMPA-type glutamate ion channels are useful as biochemical probes for structure-function studies and as drug candidates for a number of neurological disorders and diseases. Disclosed herein is the identification of an RNA inhibitor or aptamer by an in vitro evolution approach and characterization of its mechanism of inhibition on the sites of interaction by equilibrium binding and on the receptor channel-opening rate by a laser-pulse photolysis technique. The aptamer of the invention is a noncompetitive inhibitor of AMPA-type glutamate ion channels, one that selectively inhibits the GluA2Qflip AMPA receptor subunit without any effect on other AMPA receptor subunits or on kainate or NMDA receptors. Furthermore, the aptamer preferentially inhibits the closed-channel state of GluA2Qflip with a KI=1.5 ?M or by ˜15-fold over the open-channel state. The potency and selectivity of this aptamer rival those of small molecule inhibitors.

Abstract: Inhibitors of AMPA-type glutamate ion channels are useful as biochemical probes for structure-function studies and as drug candidates for a number of neurological disorders and diseases. Disclosed herein is the identification of an RNA inhibitor or aptamer by an in vitro evolution approach and characterization of its mechanism of inhibition on the sites of interaction by equilibrium binding and on the receptor channel-opening rate by a laser-pulse photolysis technique. The aptamer of the invention is a noncompetitive inhibitor of AMPA-type glutamate ion channels, one that selectively inhibits the GluA2Qflip AMPA receptor subunit without any effect on other AMPA receptor subunits or on kainate or NMDA receptors. Furthermore, the aptamer preferentially inhibits the closed-channel state of GluA2Qflip with a KI=1.5 ?M or by ˜15-fold over the open-channel state. The potency and selectivity of this aptamer rival those of small molecule inhibitors.