Abstract: A novel quinazoline compound having SOS1 inhibitory activity and uses of the quinazoline compound are disclosed. More particularly, the present invention relates to a novel quinazoline derivative compound having inhibitory activity on SOS1 binding to RAS family proteins and/or RAC1, to pharmacologically acceptable salts thereof, and to pharmaceutical compositions containing the quinazoline compound. The novel quinazoline compound has the following chemical formula 1: wherein all the variables have meaning as defined in the specification.

Abstract: Provided is a pointing data input method using a pointing device having a directional sensor for inputting pointing data accurately in an intended direction regardless of the bearing of the device, and a non-directional sensor. A device (100) includes DS (110), NDS (120), and a controller (130). The controller (130) controls pointing data on the basis of NDS data, and the pointing data is recognized by the DS (110) and is inputted based on a measured movement direction and distance. The controller (130) includes a comparator (132) for comparing the NDS data with the DS data, a modifier 134 for modifier (134) for modifying the DS data, and a means (136) for outputting the movement direction recognized by the NDS (120) as pointing data.