Abstract: A semiconductor memory device includes a third insulating pattern and a first insulating pattern on a substrate, the third insulating pattern and the first insulating pattern being spaced apart from each other in a first direction that is perpendicular to the substrate such that a bottom surface of the third insulating pattern and a top surface of the first insulating pattern face each other, a gate electrode between the bottom surface of the third insulating pattern and the top surface of the first insulating pattern, and including a first side extending between the bottom surface of the third insulating pattern and the top surface of the first insulating pattern, and a second insulating pattern that protrudes from the first side of the gate electrode by a second width in a second direction, the second direction being different from the first direction.

Abstract: Provided are biomarkers for predicting the prognosis of cervical cancer. In the case of using the biomarkers of the present disclosure, it is possible to select patients into a high-risk group, an intermediate-risk group, or a low-risk group, and thus, it is possible to provide tailored treatment for each patient according to prognosis prediction.

Abstract: The present invention relates to a bird in which human immunoglobulin G (hIgG) Fc, a protein fused with a human-derived protein and Fc, or a monoclonal antibody is expressed in a hepatocyte-specific manner, and a method for producing the same. Birds produced by the production method of the present invention can economically mass-produce human immunoglobulin Fc with enhanced anti-inflammatory effects in egg yolk and blood.

Abstract: The present invention provides a pharmaceutical composition for preventing or treating colitis comprising tegoprazan, which is a benzimidazole derivative compound, as an effective ingredient.

Abstract: Provided is a method of producing a genome-edited bird having resistance to avian influenza viruses. A method according to an aspect may enable precise inhibition of interaction between virus proteins while maintaining the original function of an ANP32A gene in a host by substituting only key amino acids of the ANP32A gene. When the method is used, by including cell lines having resistance to avian influenza viruses, new poultry and bird breeds that may not pose any biological safety issues may be efficiently developed. Thus, it is expected that the potential for industrial application is high.

Abstract: A filling material according to an embodiment of the invention includes: an outer cover material having elasticity; an expansion material being inserted into an inside of the outer cover material, wherein the expansion material being compressed when the inside of the outer cover material is evacuated; a nozzle being provided at one end of the outer cover material, wherein air is evacuated from the inside of the outer cover material or air is injected to the inside of the outer cover material to expand the outer cover material through the nozzle; and a stopper for blocking the nozzle in a state that the inside of the outer cover material is evacuated to maintain the inside of the outer cover material to be vacuous.

Abstract: A filling material according to an embodiment of the invention includes: an outer cover material having elasticity; an expansion material being inserted into an inside of the outer cover material, wherein the expansion material being compressed when the inside of the outer cover material is evacuated; a nozzle being provided at one end of the outer cover material, wherein air is evacuated from the inside of the outer cover material or air is injected to the inside of the outer cover material to expand the outer cover material through the nozzle; and a stopper for blocking the nozzle in a state that the inside of the outer cover material is evacuated to maintain the inside of the outer cover material to be vacuous.

Abstract: Disclosed is a method for preparing an embryonic stem cell (ESC)-like cell, which includes the steps of: (a) obtaining a first cell population from a mammalian tissue or body fluid, wherein the first cell population comprises adult stem cells; (b) obtaining a second somatic cell population from a mammalian tissue, wherein the mammalian tissue is different from the mammalian tissue in step (a) and the second cell population is different from the first cell population; (c) coculturing the first cell population and the second cell population in a medium for a period of time sufficient to form a colony from either the first cell population or the second cell population; and (d) subculturing a cell from the colony in a medium for a period time sufficient to prepare the ESC-like cell.

Abstract: The present invention relates to a method for producing a preantral follicle-derived embryonic stem cell and a preantral follicle-derived embryonic stem cell. The present method comprises the steps of (a) obtaining a preantral follicle from mammalian ovaries; (b) growing the preantral follicle in vitro; (c) maturing an oocyte in vitro present in the cultured preantral follicle; (d) activating the matured oocyte for parthenogenesis; (e) culturing the activated oocyte to form a blastocyst; and (f) culturing inner cell mass (ICM) cells of the blastocyst to produce the preantral follicle-derived embryonic stem cell.

Abstract: Disclosed is a method for preparing an embryonic stem cell (ESC)-like cell, which includes the steps of: (a) obtaining a first cell population from a mammalian tissue or body fluid, wherein the first cell population comprises adult stem cells; (b) obtaining a second somatic cell population from a mammalian tissue, wherein the mammalian tissue is different from the mammalian tissue in step (a) and the second cell population is different from the first cell population; (c) coculturing the first cell population and the second cell population in a medium for a period of time sufficient to form a colony from either the first cell population or the second cell population; and (d) subculturing a cell from the colony in a medium for a period time sufficient to prepare the ESC-like cell.

Abstract: The present invention relates to a method for long-term culturing of avian spermatogonial stem cells, which comprises the steps of: (a) preparing an avian testis; (b) isolating a population of testicular cells from said avian testis; and (c) culturing said avian spermatogonial stem cells in said population of testicular cells on a feeder cell layer in a medium containing a cell growth factor, a population of avian spermatogonial stem cells and a method for producing transgenic ayes.

Abstract: An RF (radio frequency) coil assembly of a magnetic resonance imaging (MRI) system, which has a spiral-shaped coil and a plurality of sections. In one embodiment, an RF coil of a magnetic resonance imaging (MRI) system has a plurality of ring-shaped end-rings arranged vertically and a plurality of rods. Each of the rods are connected to the plurality of end-rings. Adjacent end-rings of the plurality of end-rings forms respective coil sections and each of the coil sections has switching blocks located between adjacent rods of the plurality of rods. The switching blocks are operable to control the continuity status of the plurality of rods in the respective coil section.

Abstract: The present invention relates to a method for improving the germline transmission efficiency of avian primordial germ cells (PGCs), and methods for producing avian chimeras and transgenic using it. The present method comprises the steps of (a) isolating primordial germ cells (PGCs) from an avian embryonic gonad; and (b) culturing said PGCs in vitro for at least 5 days. According to the present method, the germline transmission efficiency of PGCs can be dramatically improved in a feasible manner.

Abstract: A plasma display panel and method are provided to reduce noise. The plasma display panel may include a first substrate including a first electrode, a second substrate facing the first substrate, the second substrate including a second electrode, and barrier ribs arranged between the first substrate and the second substrate to partition discharge cells. The plasma display panel may also include a first adhesion layer arranged between the first substrate and each of the barrier ribs, and a second adhesion layer arranged between the first substrate and the second substrate.

Abstract: The present invention relates to a nucleotide sequence of a testis-specific gene in avian species and a method for identifying a testicular cell of avian species.

Abstract: An improved distribution system and method of operating the same are provided. In one embodiment, the distribution system includes a plate for loading a plurality of substrates thereon, a first transfer assembly for transferring the substrates from the plate to a conveyer, and a distribution assembly for distributing the substrates transferred by the conveyer to a first testing assembly and a second testing assembly. The distribution assembly includes a first sub-conveyer and a second sub-conveyer, and the outlet of one of the first sub-conveyer and the second sub-conveyer corresponds to the inlet of one of the first testing assembly and the second testing assembly.

Abstract: An improved distribution system and method of operating the same are provided. In one embodiment, the distribution system includes a plate for loading a plurality of substrates thereon, a first transfer assembly for transferring the substrates from the plate to a conveyer, and a distribution assembly for distributing the substrates transferred by the conveyer to a first testing assembly and a second testing assembly. The distribution assembly includes a first sub-conveyer and a second sub-conveyer, and the outlet of one of the first sub-conveyer and the second sub-conveyer corresponds to the inlet of one of the first testing assembly and the second testing assembly.

Abstract: The present invention relates to (a) variable regions of heavy and light chains of an antibody specific to a surface antigen in sporozoite of Eimeria spp.; (b) a recombinant scFV (single chain variable fragment) antibody prepared using the variable regions; (c) a method for preparing a recombinant scFv antibody; and (d) an expression vector for expressing a recombinant scFv antibody.

Abstract: The present invention relates to (a) variable regions of heavy and light chains of an antibody specific to a surface antigen in sporozoite of Eimeria spp.; (b) a recombinant scFV (single chain variable fragment) antibody prepared using the variable regions; (c) a method for preparing a recombinant scFv antibody; and (d) an expression vector for expressing a recombinant scFv antibody.

Abstract: The present invention relates to a method for transfection of avian primordial germ cells which comprises a step of electroporating a foreign gene into avian primordial germ cells after addition of dimethylsulfoxide( “DMSO”) to culture medium containing the cells, and a method for production of transgenic Aves by employing the avian primordial germ cells transfected thereby. The DMSO-electroporation method of the invention has various advantages over the conventional transfection methods in light of high transfection efficiency, safety, and simple manipulation. Accordingly, a large number of primordial germ cells transfected with a gene of interest can be efficiently produced by the invention, which, in turn, may increase the rate of transfer of exogenous DNA into recipient embryos.