Patents by Inventor Jae-yoon Ryu

Jae-yoon Ryu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition for preventing and treating transplant rejection or transplant rejection diseases, comprising novel compound and calcineurin inhibitor
    Patent number: 11969397
    Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: April 30, 2024
    Assignee: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Mi-La Cho, Dong-Yun Shin, Jong-Young Choi, Chul-Woo Yang, Sung-Hwan Park, Seon-Yeong Lee, Min-Jung Park, Joo-Yeon Jhun, Se-Young Kim, Hyeon-Beom Seo, Jae-Yoon Ryu, Keun-Hyung Cho
  • COMPOSITION FOR PREVENTING AND TREATING TRANSPLANT REJECTION OR TRANSPLANT REJECTION DISEASES, COMPRISING NOVEL COMPOUND AND CALCINEURIN INHIBITOR
    Publication number: 20220031637
    Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.
    Type: Application
    Filed: November 7, 2019
    Publication date: February 3, 2022
    Inventors: Mi-La CHO, Dong-Yun SHIN, Jong-Young CHOI, Chul-Woo YANG, Sung-Hwan PARK, Seon-Yeong LEE, Min-Jung PARK, Joo-Yeon JHUN, Se-Young KIM, Hyeon-Beom SEO, Jae-Yoon RYU, Keun-Hyung CHO
  • RAPO strain for alleviating, treating or preventing rheumatoid arthritis and composition containing the same
    Patent number: 11135254
    Abstract: Disclosed are a novel Bifidobacterium longum RAPO (Accession No.: KCTC 13773BP) and a composition for alleviating, treating or preventing rheumatoid arthritis containing Bifidobacterium longum RAPO (Accession No.: KCTC 13773BP) selected herein.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: October 5, 2021
    Assignees: THE CATHOLIC UNIVERSITY OF KOREA, BIFIDO CO., LTD.
    Inventors: Geun Eog Ji, Yun Ju Jeong, Sang Jun Park, Su Young Yang, Hyon Ha Lee, Sung Hwan Park, Mi La Cho, Ji Hyeon Ju, Seung Ki Kwok, Joo Ha Lee, Ji Won Kim, Seon Yeong Lee, Jun Geol Ryu, Joo Yeon Jhun, Jae Yoon Ryu
  • BIFIDOBACTERIUM LONGUM RAPO STRAIN FOR ALLEVIATING, TREATING OR PREVENTING RHEUMATOID ARTHRITIS AND COMPOSITION CONTAINING THE SAME
    Publication number: 20210154244
    Abstract: Disclosed are a novel Bifidobacterium longum RAPO (Accession No.: KCTC 13773BP) and a composition for alleviating, treating or preventing rheumatoid arthritis containing Bifidobacterium longum RAPO (Accession No.: KCTC 13773BP) selected herein.
    Type: Application
    Filed: October 15, 2019
    Publication date: May 27, 2021
    Inventors: Geun Eog JI, Yun Ju JEONG, Sang Jun PARK, Su Young YANG, Hyon Ha LEE, Sung Hwan PARK, Mi La CHO, Ji Hyeon JU, Seung Ki KWOK, Joo Ha LEE, Ji Won KIM, Seon Yeong LEE, Jun Geol RYU, Joo Yeon JHUN, Jae Yoon RYU
  • Composition containing for alleviating, preventing or treating rheumatoid arthritis
    Patent number: 10617725
    Abstract: Provided is a composition containing Bifidobacterium for alleviating, preventing or treating rheumatoid arthritis. The Bifidobacterium bifidum ATT newly isolated according to the present invention is useful as a rheumatoid arthritis medicine or a probiotic material for alleviating rheumatoid arthritis owing to potent efficacy in treating rheumatoid arthritis.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: April 14, 2020
    Assignees: BIFIDO CO., LTD., THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Geun Eog Ji, Yunju Jeong, Hui Fang, Bin Kwon, Sung-Hwan Park, Mi-La Cho, Ji-Hyeon Ju, Seung-Ki Kwok, Jennifer Lee, Ji-Won Kim, Seon-Yeong Lee, Jun-Geol Ryu, Joo-Yeon Jhun, Jae-yoon Ryu, Hyeon-Beom Seo
  • COMPOSITION CONTAINING BIFIDOBACTERIUM FOR ALLEVIATING, PREVENTING OR TREATING RHEUMATOID ARTHRITIS
    Publication number: 20190231830
    Abstract: Provided is a composition containing Bifidobacterium for alleviating, preventing or treating rheumatoid arthritis. The Bifidobacterium bifidum ATT newly isolated according to the present invention is useful as a rheumatoid arthritis medicine or a probiotic material for alleviating rheumatoid arthritis owing to potent efficacy in treating rheumatoid arthritis.
    Type: Application
    Filed: May 11, 2018
    Publication date: August 1, 2019
    Applicants: BIFIDO CO., LTD., THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Geun Eog JI, Yunju JEONG, Hui FANG, KWON, Bin KWON, Bin, Sung-Hwan PARK, Mi-La CHO, Ji-Hyeon JU, Seung-Ki KWOK, Jennifer LEE, Ji-Won KIM, Seon-Yeong LEE, Jun-Geol RYU, Joo-Yeon JHUN, Jae-yoon RYU, Hyeon-Beom SEO