Patents by Inventor Jaehon Kim

Jaehon Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for reducing an alpha-keto ester
    Patent number: 7109004
    Abstract: A process for preparing (R)-hydroxy ester (II) from alpha-keto ester I comprising adding the alpha-keto ester I to a mixture comprising the ketoreductase enzyme and non-ketoreductase enzyme components, wherein the ketoreductase enzyme has a molecular weight between 36000 and 38000, and wherein the ketoreductase enzyme has an N-terminal amino acid sequence selected from the group of sequences consisting of (SEQ. ID NO. 1) Ala-Ile-Pro-Asp-Asn-Ala-Val-Leu-Glu-Gly-Ser-Leu- Val-Lys-Val-Thr-Gly-Ala-Asn-Gly (SEQ. ID NO. 4) Met-Ala-Ile-Pro-Asp-Asn-Ala-Val-Leu-Glu-Gly-Ser- Leu-Val-Lys-Val-Thr-Gly-Ala-Asn-Gly, and (SEQ. ID NO. 2) Met-Ala-Lys-Ile-Asp-Asn-Ala-Val-Leu-Pro-Glu-Gly- Ser-Leu-Val-Leu-Val-Thr-Gly-Ala-Asn-Gly.
    Type: Grant
    Filed: July 8, 2003
    Date of Patent: September 19, 2006
    Assignee: Merck & Co., Inc.
    Inventors: Jeffrey C. Moore, Michael G. Sturr, Kathleen McLaughlin, Jaehon Kim
  • Process for preparation of (6S,9R)-11-OXO-5,6,7,8,9,10-hexahydro-6,9-methanobenzocyclooctene
    Publication number: 20050112738
    Abstract: The present invention is directed to processes for the preparation of (6S,9R)-11-oxo-5,6,7,8,9,10-hexahydro-6,9-methanobenzocyclooctene. Racemic 11-oxo-5,6,7,8,9, 10-hexahydro-6,9-methanobenzocyclooctene has the Chemical Abstracts registry number 82799-14-2 and is useful in the preparation of compounds with pharmacological activity.
    Type: Application
    Filed: September 30, 2004
    Publication date: May 26, 2005
    Inventors: Jeffrey Moore, Michael Sturr, Matthew Truppo, Jaehon Kim
  • Process for reducing an alpha-keto ester
    Publication number: 20040101937
    Abstract: A process for preparing (R)-hydroxy ester (II) 1
    Type: Application
    Filed: July 8, 2003
    Publication date: May 27, 2004
    Inventors: Jeffrey C. Moore, Michael G. Sturr, Kathleen McLaughlin, Jaehon Kim