Abstract: The display device includes a display panel and a pixel. A compensator configured to calculate a degradation rate of the pixel based on an input gray level of first image data, and compensates the first image data based on the degradation rate to generate second image data. A data driver configured to generate a data signal based on the second image data and configured to supply the data signal to the pixel. The pixel includes a first element group and a second element group connected in series to each other, the first element group includes at least one first light emitting element, and the second element group includes at least one second light emitting element. The compensator is to calculate the degradation rate by applying first information on the number of the first light emitting elements and second information on the number of the second light emitting elements.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a COX2 acetylating agent as an active ingredient and, more particularly, to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising, as an active ingredient, a COX2 acetylating agent which exhibits an effect of inhibiting the deposition of amyloid-? in brain neurons, reducing excessive neuroinflammatory responses, and increasing the phagocytosis of amyloid-? in microglial cells. The pharmaceutical composition for preventing or treating neurodegenerative diseases comprising the COX2 acetylating agent as an active ingredient has the effects of alleviating neuroinflammation by promoting COX2 acetylation in neurons and secreting specialized pro-resolving mediators (SPMs) and thus, can be very useful in the development of a preventive or therapeutic agent for neurodegenerative diseases.

Abstract: An integrated water pump and valve device in which a water pump and a valve are integrally controlled by a single controller, and the water pump and the valve are integrated, thereby reducing an overall size.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a COX2 acetylating agent as an active ingredient and, more particularly, to a pharmaceutical composition for preventing or treating neurodegenerative diseases comprising, as an active ingredient, a COX2 acetylating agent which exhibits an effect of inhibiting the deposition of amyloid-? in brain neurons, reducing excessive neuroinflammatory responses, and increasing the phagocytosis of amyloid-? in microglial cells. The pharmaceutical composition for preventing or treating neurodegenerative diseases comprising the COX2 acetylating agent as an active ingredient has the effects of alleviating neuroinflammation by promoting COX2 acetylation in neurons and secreting specialized pro-resolving mediators (SPMs) and thus, can be very useful in the development of a preventive or therapeutic agent for neurodegenerative diseases.

Abstract: An integrated water pump and valve device in which a water pump and a valve are integrally controlled by a single controller, and the water pump and the valve are integrated, thereby reducing an overall size.

Abstract: An integrated device of a pump and a valve is disclosed. The integrated device of a pump and a valve includes a drive unit, a valve assembly mounted on the drive unit and configured to be switchable to a first position or a second position by the drive unit, a pump mounted on the drive unit, and a controller configured to control operation of the drive unit and the pump. The valve assembly includes a plurality of inlets and a plurality of outlets. At the first position and the second position of the valve assembly, different fluid passages are formed in the valve assembly. The pump is configured to communicate with the valve assembly to allow a flow of fluid through the valve assembly.

Abstract: The present invention relates to a use of a triazole compound as a ghrelin receptor agonist and, more specifically, to a composition for preventing or treating diseases mediated by the ghrelin receptor, the composition being of a triazole compound which strongly binds to the ghrelin receptor with very high specificity. The compound provided by the present invention exhibits a strong binding force to the ghrelin receptor with very high specificity, and thus may be very usefully employed for preventing or developing a therapeutic agent for diseases mediated by the ghrelin receptor.

Abstract: The present invention relates to a novel use for HDL-ApoM-S1P (a high density lipoprotein in which apolipoprotein M is impregnated with sphingosine-1-phosphate), and more particularly, to using HDL-ApoM-S1P to prevent, improve, or treat degenerative brain disorders (in particular, Alzheimer's disease), cognitive disorders, learning disabilities, and memory disorders, and using HDL-ApoM-S1P to improve cognitive ability, learning ability, and memory. The HDL-ApoM-S1P according to the present invention not only alleviates neuroinflammation but also significantly exhibits improvement effects of cognitive disorder, learning disability, and memory disorder with respect to individuals suffering from degenerative brain disorders (in particular, Alzheimer's disease), and exhibits an effect of greatly reducing amyloid beta and tau deposition. Moreover, increased HDL-ApoM-S1P in the body also has an excellent effect of improving the cognitive, learning, and memory abilities of non-disabled individuals.

Abstract: A display device includes an afterimage compensator generating output grayscales by applying at least one of first and second weights to input grayscales when the input grayscales correspond to a still image, and pixels displaying an image based on the output grayscales. The afterimage compensator applies the first weight having an initial value greater than 1 to the input grayscales of a first group, and converges the first weight to 1, and applies the second weight having initial values less than 1 to the input grayscales of a second group, and converges the second weights to 1.

Abstract: A display apparatus includes a display panel, a driving controller and a data driver. The driving controller processes input image data according to a variable input frequency and generates a data signal having a varied frame length. The data driver converts the data signal into a data voltage and outputs the data voltage to the display panel. The driving controller determines a variable frequency mode and generates an asymmetric data signal including a positive data signal and a negative data signal which are asymmetric with respect to a common voltage for a same grayscale value in the variable frequency mode.

Abstract: The present invention relates to an antibody for detecting acetylation of COX2 protein, and uses thereof, and more specifically, to an antibody that specifically recognizes the acetylation of S565 residue of the COX2 protein; and uses thereof for diagnosing neurodegenerative diseases or inflammatory diseases. An antibody or a functional fragment thereof according to the present invention specifically binds to an acetylated residue of COX2 protein, and can thus be very effectively used for diagnosing neurodegenerative diseases, inflammatory diseases, and the like in which the degree of acetylation of S565 residue of the COX2 protein is reduced.

Abstract: A display device includes a display part, a degradation compensator that generates a first compensated grayscale value by compensating for a first grayscale value corresponding to a first pixel, and generates a second compensated grayscale value by compensating for a second grayscale value corresponding to a second pixel, and a data driver that generates a first data signal based on the first compensated grayscale value to supply the first data signal to the first pixel, and generates a second data signal based on the second compensated grayscale value to supply the second data signal to the second pixel. A second degradation curve is defined by a first degradation coefficient corresponding to a first degradation curve, and a second degradation coefficient corresponding to a first estimated degradation curve for the light conversion particles of a second color calculated by applying the first degradation curve.

Abstract: An afterimage compensator includes: a pixel data generator configured to generate characteristic data for one or more pixels from among a plurality of pixels by using a captured image; a stress accumulator configured to generate an accumulated stress for the one or more pixels in which stress corresponding to the one or more pixels is accumulated based on an image signal of a voltage domain; a domain converter configured to convert the accumulated stress for the one or more pixels from the voltage domain to accumulated stress data for the one or more pixels of a grayscale domain; and a compensator configured to generate compensation data using the characteristic data for the one or more pixels and the accumulated stress data for the one or more pixels.

Abstract: A display device includes an afterimage compensator generating output grayscales by applying at least one of first and second weights to input grayscales when the input grayscales correspond to a still image, and pixels displaying an image based on the output grayscales. The afterimage compensator applies the first weight having an initial value greater than 1 to the input grayscales of a first group, and converges the first weight to 1, and applies the second weight having initial values less than 1 to the input grayscales of a second group, and converges the second weights to 1.

Abstract: A display apparatus includes a display panel, a driving controller and a data driver. The display panel is configured to display an image. The driving controller is configured to generate a compensated image data for compensating a decrease of a luminance of an edge portion of the display panel based on input image data. The data driver is configured to output a data voltage to the display panel based on the compensated image data. The driving controller is configured to generate the compensated image data by comparing a maximum value among subpixel grayscale values of the input image data to which a luminance compensating coefficient is applied and a maximum grayscale value of the input image data. The luminance compensating coefficient is configured to be determined according to a location in the display panel.

Abstract: The present invention relates to a amyotrophic lateral sclerosis (ALS) diagnostic composition using acid sphingomyelinase (ASM), and a method for detecting diagnostic markers and, more specifically, to a method and a composition for detecting markers for ALS, the method comprising the steps of: (a) providing a sample of a subject; (b) measuring the ASM expression level or the enzyme activation level in the sample; (c) determining that a subject, of which the ASM expression level or the enzyme activation level is increased compared to that of a normal person, has ALS. According to the investigation of the present inventors, the activity of ASM, among lipids and enzymes related to the sphingolipid metabolism, is specifically increased in a sample of an ALS patient compared to that of a normal person. ASM can be used as a marker for diagnosing ALS, thereby enabling the development of a novel and effective diagnostic reagent.

Abstract: Disclosed is a wing in which, while a continuous surface is maintained, a chord length and camber of an airfoil may be modified via only a rotational drive alone, whereby a structure is simple and aerodynamic efficiency may be improved.

Abstract: A display apparatus includes a display panel, a driving controller and a data driver. The display panel is configured to display an image. The driving controller is configured to generate a compensated image data for compensating a decrease of a luminance of an edge portion of the display panel based on input image data. The data driver is configured to output a data voltage to the display panel based on the compensated image data. The driving controller is configured to generate the compensated image data by comparing a maximum value among subpixel grayscale values of the input image data to which a luminance compensating coefficient is applied and a maximum grayscale value of the input image data. The luminance compensating coefficient is configured to be determined according to a location in the display panel.

Abstract: A display apparatus includes a display panel including a plurality of pixels, and a driver which receives input image data, generates final image data by compensating the input image data to increase luminances of pixels disposed in at least one edge portion of the display panel among the plurality of pixels, and drives the display panel based on the final image data. The input image data for a pixel of the pixels is compensated based on a compensation constant determined according to a position of the pixel when the input image data for the pixel represents a gray level higher than or equal to a first reference gray level, and is compensated based on a reduced compensation constant that is reduced from the determined compensation constant when the input image data for the pixel represents the gray level lower than the first reference gray level.

Abstract: The present invention relates to a novel phenylsulfonyl oxazole derivative and a use thereof and specifically, to a compound represented by Chemical Formula 1 in the present specification or a pharmaceutically acceptable salt thereof, and to a use thereof for prevention, treatment, or improvement of neurodegenerative disease.