Abstract: Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the liposomal irinotecan (MM-398) is co-administered with 5-fluorouracil and leucovorin.

Abstract: A sputter trap formed on at least a portion of a sputtering chamber component has a plurality of particles and a particle size distribution plot with at least two different distributions. A method of forming a sputter trap having a particle size distribution plot with at least two different distributions is also provided.

Abstract: A sputter trap formed on at least a portion of a sputtering chamber component has a plurality of particles and a particle size distribution plot with at least two different distributions. A method of forming a sputter trap having a particle size distribution plot with at least two different distributions is also provided.

Abstract: A sputtering chamber component including a front surface, a back surface opposite the front surface, and a sputter trap formed on at least a portion of the back surface, and a coating of metallic particles formed on the sputter trap. The coating has a thickness from about 0.025 mm to about 2.54 mm (0.001 inches to about 0.1 inches) and is substantially free of impurities, and the particles of the coating are substantially diffused.

Abstract: Provided are methods for treating breast cancer in a patient by administering effective amounts of liposomal irinotecan sucrosofate (MM-398). The breast cancer may be triple negative breast cancer (TNBC), estrogen receptor/progesterone receptor (ER/PR) positive breast cancer, ER-positive breast cancer, or PR-positive breast cancer, or metastatic breast cancer.

Abstract: Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the liposomal irinotecan (MM-398) is co-administered with 5-fluorouracil and leucovorin.

Abstract: Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the liposomal irinotecan (MM-398) is co-administered with 5-fluorouracil and leucovorin.

Abstract: A sputtering target comprising a sputtering material and having a non-planar sputtering surface prior to erosion by use in a sputtering system, the non-planar sputtering surface having a circular shape and comprising a central axis region including a concave curvature feature at the central axis region. The central axis region having a wear profile after erosion by use in a sputtering system for at least 1000 kWhrs including a protuberance including a first outer circumferential wear surface having a first slope. A reference, protruding convex curvature feature for a reference target after sputtering use for the same time includes a second outer circumferential wear surface having a second slope. The protuberance provides a sputtered target having reduced shadowing relative to the reference, protruding convex curvature feature, wherein the first slope is less steep than a second slope.

Abstract: A sputter trap formed on at least a portion of a sputtering chamber component has a plurality of particles and a particle size distribution plot with at least two different distributions. A method of forming a sputter trap having a particle size distribution plot with at least two different distributions is also provided.

Abstract: A display driving integrated circuit is provided which drives a plurality of gate lines included in a display panel. The display driving integrated circuit includes: a charge pump configured to change a voltage from an external power source to generate an output voltage; and a gate line driver configured to drive the plurality of gate lines based on the output voltage. The charge pump may operate in one of a low-current mode and a high-current mode based on a size of the display panel.

Abstract: Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the liposomal irinotecan (MM-398) is co-administered with 5-fluorouracil and leucovorin.

Abstract: Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the liposomal irinotecan (MM-398) is co-administered with 5-fluorouracil and leucovorin.

Abstract: A valve may include a housing forming one inlet and at least one outlet, an operating unit mounted in the housing, and performing expansion or contraction in accordance with a temperature of a flowing working fluid to selectively connect the at least outlet with the one inlet for exhausting the flowing working fluid outside of the housing, wherein the operating unit includes a sliding member slidably inserted into the interior of the housing, a flange member forming a penetration hole and fixedly mounted inside of the sliding member, a rod movably inserted into the penetration hole of the flange member, and a deformable member fixed at the penetration hole of the flange member and expanded or contracted in accordance with a temperature of the flowing working fluid.

Abstract: The present invention makes it possible to integrate and control in one circuit the systems, such as electric power components, a driving motor, a stack, and an AC condenser which have the maximum enthalpy under similar operational temperature and use conditions, by using an integrated radiator. Therefore, it is possible to minimize air-through resistance of the radiator for cooling the stack and the electric power components and ensure smooth and stable cooling performance of the stack, electric power components, and AC condenser while improving fuel efficiency by reducing the condensation pressure of the air conditioner. Further, it is possible to improve cooling efficiency by non-repeatedly arranging heat exchangers, and reduce the weight of a vehicle, volume of the parts, and the manufacturing cost, by avoiding using too many parts, such as a radiator, a water pump, and a reservoir tank.

Abstract: A can type of heat exchanger may include a housing formed as a cylinder, having a mounting space at the inside, and formed with at least one inlet and at least one outlet, a heat dissipation unit mounted in the mounting space of the housing, receiving operating fluids from the inlet, and the operating fluids heat-exchanging with each other, a separating plate separating the mounting space and inside of the mounting portion, and a valve unit, selectively opening and closing the mounting space or a bypass passageway separated by the separating plate using linear displacement which is generated when expansion and contraction occur according to the temperature of the coolant flowing from the inlet, and adjusting flow of the operating fluids.

Abstract: A valve for a vehicle provided between a transmission and an oil cooler for cooling transmission oil may include a valve housing in which a first inflow port connected to the transmission and an exhaust port connected to the oil cooler are formed on both sides facing each other and a bypass port connected to the transmission and a second inflow port connected to the oil cooler are formed at a position spaced apart from the first inflow port and the exhaust port along a length direction of the valve housing, and a control unit that is mounted inside the valve housing selectively connects the first inflow port to the exhaust port or the bypass port while expansion or contraction is performed depending on a temperature of the transmission oil, and selectively closes the exhaust port to control a flow stream of the transmission oil.

Abstract: A sputtering target assembly for use in a vapor deposition apparatus, the sputtering target assembly comprising a sputtering surface; a sidewall extending from the sputtering surface at an angle to the sputtering surface; a particle trap formed of a roughness located along the sidewall and extending radially from the sputtering surface, wherein the roughness of the particle trap has a macrostructure and a microstructure.

Abstract: Provided are methods for treating pancreatic cancer in a patient by administering liposomal irinotecan (MM-398) alone or in combination with additional therapeutic agents. In one embodiment, the liposomal irinotecan (MM-398) is co-administered with 5-fluorouracil and leucovorin.

Abstract: A liposome-encapsulated formulation of irinotecan can be used for the treatment of pancreatic cancer in combination with 5-fluorouracil and leucovorin, including treatment of patients diagnosed with metastatic adenocarcinoma of the pancreas who have been previously treated with gemcitabine.

Abstract: Provided are methods for treating breast cancer in a patient by administering effective amounts of liposomal irinotecan sucrosofate (MM-398). The breast cancer may be triple negative breast cancer (TNBC), estrogen receptor/progesterone receptor (ER/PR) positive breast cancer, ER-positive breast cancer, or PR-positive breast cancer, or metastatic breast cancer.