Patents by Inventor Jagan V. Valluri

Jagan V. Valluri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for stem cell production and therapy
    Patent number: 8993231
    Abstract: The present invention relates to methods for rapidly expanding a stem cell population with or without culture supplements in simulated microgravity conditions. The present invention relates to methods for rapidly increasing the life span of stem cell populations without culture supplements in simulated microgravity conditions. The present invention also relates to methods for increasing the sensitivity of cancer stem cells to chemotherapeutic agents by culturing the cancer stem cells under microgravity conditions and in the presence of omega-3 fatty acids. The methods of the present invention can also be used to proliferate cancer cells by culturing them in the presence of omega-3 fatty acids. The present invention also relates to methods for testing the sensitivity of cancer cells and cancer stem cells to chemotherapeutic agents by culturing the cancer cells and cancer stem cells under microgravity conditions.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: March 31, 2015
    Assignee: Marshall University Research Corporation
    Inventors: Pier Paolo Claudio, Jagan V. Valluri
  • Methods for Stem Cell Production and Therapy
    Publication number: 20100062435
    Abstract: The present invention relates to methods for rapidly expanding a stem cell population with or without culture supplements in simulated microgravity conditions. The present invention relates to methods for rapidly increasing the life span of stem cell populations without culture supplements in simulated microgravity conditions. The present invention also relates to methods for increasing the sensitivity of cancer stem cells to chemotherapeutic agents by culturing the cancer stem cells under microgravity conditions and in the presence of omega-3 fatty acids. The methods of the present invention can also be used to proliferate cancer cells by culturing them in the presence of omega-3 fatty acids. The present invention also relates to methods for testing the sensitivity of cancer cells and cancer stem cells to chemotherapeutic agents by culturing the cancer cells and cancer stem cells under microgravity conditions.
    Type: Application
    Filed: March 17, 2009
    Publication date: March 11, 2010
    Applicant: Marshall University Research Corporation
    Inventors: Pier Paolo Claudio, Jagan V. Valluri
  • Microgravity bioreactor systems for production of bioactive compounds and biological macromolecules
    Publication number: 20080138828
    Abstract: The present invention relates to compositions and methods of plant, fungal and bacterial cell culture that can be effectively utilized for three-dimensional plant, fungal, and bacterial cell growth and production of bioactive compounds of interest. The culture methods employ a microgravity environment such that rapid establishment and expansion of cells into tissue constructs occurs influencing expression of biological macromolecules and biopharmaceuticals. The present invention is further directed to a method for the in vitro cultivation of plant, fungal, and bacterial cells in a liquid nutrient medium in modeled microgravity with potential for large scale manipulations.
    Type: Application
    Filed: December 8, 2006
    Publication date: June 12, 2008
    Inventors: Jagan V. Valluri, Steven R. Gonda