Publication number: 20090293137
Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO218, PRO228, PRO271, PRO273, PRO295, PRO302, PRO305, PRO326, PRO386, PRO655, PRO162, PRO788, PRO792, PRO940, PRO941, PRO1004, PRO1012, PRO 1016, PRO474, PRO5238, PRO1069, PRO1111, PRO1113, PRO1130, PRO1195, PRO1271, PRO1865, PRO1879, PRO3446, PRO3543, PRO4329, PRO4352, PRO5733, PRO9859, PRO9864, PRO9904, PRO9907, PRO10013, PRO90948, PRO28694, PRO16089, PRO19563, PRO19675, PRO20084, PRO21434, PRO50332, PRO38465 or PRO346 genes.
Type:
Application
Filed:
November 16, 2006
Publication date:
November 26, 2009
Applicant:
Genentech, Inc.
Inventors:
Katherin E. Combs, Frederic J. de Sauvage, Liangfen Fan, Ellen Filvaroff, Allison A. B. Horner, Bryan Irving, Jagath Reddy Juntula, Erin Marie Massey, Dina Rebecca McLain, Laurie Jeanette Minze, Charles Montgomery, Bobby Joe Payne, Heidi Philips, Carolina Rangel, Tracy E. W. Sevaux, Zheng-Zheng Shi, Mary Jean Sparks, Joy Anne Stala, Teresa G. Townsend, Peter Vogel