Patents by Inventor Jagesh Vijaykumar Shah

Jagesh Vijaykumar Shah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR COMPARTMENT-SPECIFIC CARGO DELIVERY
    Publication number: 20230068547
    Abstract: Fusosome compositions and methods are described herein.
    Type: Application
    Filed: November 14, 2019
    Publication date: March 2, 2023
    Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael Travis Mee, Neal Francis Gordon, Jagesh Vijaykumar Shah, Kyle Marvin Trudeau, Brigham Jay Hartley
  • FUSOSOME COMPOSITIONS FOR HEMATOPOIETIC STEM CELL DELIVERY
    Publication number: 20230048166
    Abstract: The present disclosure provides, at least in part, methods and compositions for in vivo fusosome delivery. In some embodiments, the fusosome comprises a combination of elements that promote specificity for target cells, e.g., one or more of a fusogen, a positive target cell-specific regulatory element, and a non-target cell-specific regulatory element. In some embodiments, the fusosome comprises one or more modifications that decrease an immune response against the fusosome.
    Type: Application
    Filed: November 14, 2019
    Publication date: February 16, 2023
    Inventors: Geoffrey A. von Maltzahn, Jacob Rosenblum Rubens, Jagesh Vijaykumar Shah, Albert Ruzo Matias, Ferdinando Pucci, John Miles Milwid, Michael Travis Mee, Neal Francis Gordon
  • FUSOSOME COMPOSITIONS FOR T CELL DELIVERY
    Publication number: 20230043255
    Abstract: The present disclosure provides, at least in part, methods and compositions for in vivo fusosome delivery. In some embodiments, the fusosome comprises a combination of elements that promote specificity for target cells, e.g., one or more of a fusogen, a positive target cell-specific regulatory element, and a non-target cell-specific regulatory element. In some embodiments, the fusosome comprises one or more modifications that decrease an immune response against the fusosome.
    Type: Application
    Filed: November 14, 2019
    Publication date: February 9, 2023
    Inventors: Geoffrey A. von Maltzahn, Jacob Rosenblum Rubens, Jagesh Vijaykumar Shah, Albert Ruzo Matias, Ferdinando Pucci, John Miles Milwid, Michael Travis Mee, Neal Francis Gordon
  • USE OF CD8-TARGETED VIRAL VECTORS
    Publication number: 20220241328
    Abstract: Provided herein are methods of transducing resting or non-activated T cells using CD8-targeted viral vectors.
    Type: Application
    Filed: January 10, 2022
    Publication date: August 4, 2022
    Applicant: Sana Biotechnology, Inc.
    Inventors: Christopher BANDORO, Patricia CRUITE, Kutlu ELPEK, Akinola Olumide EMMANUEL, Lauren Pepper MACKENZIE, Jagesh Vijaykumar SHAH, Kyle Marvin TRUDEAU
  • FUSOSOME COMPOSITIONS FOR CNS DELIVERY
    Publication number: 20220008557
    Abstract: The present disclosure provides, at least in part, methods and compositions for in vivo fusosome delivery. In some embodiments, the fusosome comprises a combination of elements that promote specificity for target cells, e.g., one or more of a fusogen, a positive target cell-specific regulatory element, and a non-target cell-specific regulatory element. In some embodiments, the fusosome comprises one or more modifications that decrease an immune response against the fusosome.
    Type: Application
    Filed: November 14, 2019
    Publication date: January 13, 2022
    Inventors: Geoffrey A. von Maltzahn, Jacob Rosenblum Rubens, Jagesh Vijaykumar Shah, Albert Ruzo Matias, Ferdinando Pucci, John Miles Milwid, Michael Travis Mee, Neal Francis Gordon
  • TARGETED LIPID PARTICLES AND COMPOSITIONS AND USES THEREOF
    Publication number: 20210353543
    Abstract: Provided herein are lipid particles containing a lipid bilayer enclosing a lumen or cavity, a henipavirus F protein molecule or biologically active portion thereof, and a targeted envelope protein containing a henipavirus envelope attachment glycoprotein G (G protein) or biologically active portion thereof and a binding domain, such as a single domain antibody (sdAb) variable domain. Also provided herein are targeted envelope proteins containing a G protein fused or linked to a binding domain, such as a sdAb variable domain, and polynucleotides encoding such proteins. Also provided are producer cells and compositions containing such targeted lipid particles and methods of making and using the targeted lipid particles.
    Type: Application
    Filed: March 30, 2021
    Publication date: November 18, 2021
    Applicants: Sana Biotechnology, Inc., Flagship Pioneering Innovations V, Inc.
    Inventors: Kyle Marvin TRUDEAU, Christopher BANDORO, Lauren Pepper MACKENZIE, Jagesh Vijaykumar SHAH, Geoffrey A. VON MALTZAHN, Jacob Rosenblum RUBENS, Michael Travis MEE
  • FUSOSOME COMPOSITIONS AND USES THEREOF
    Publication number: 20210228627
    Abstract: The present disclosure provides, at least in part, methods and compositions for in vivo fusosome delivery. In some embodiments, the fusosome comprises a combination of elements that promote specificity for target cells, e.g., one or more of a re-targeted fusogen, a positive target cell-specific regulatory element, and a non-target cell-specific regulatory element. In some embodiments, the fusosome comprises one or more modifications that decrease an immune response against the fusosome.
    Type: Application
    Filed: May 15, 2019
    Publication date: July 29, 2021
    Inventors: Geoffrey A. von Maltzahn, Jacob Rosenblum Rubens, Michael Travis Mee, John Miles Milwid, Neal Francis Gordon, Jagesh Vijaykumar Shah, Kyle Marvin Trudeau, Brigham Jay Hartley, Peter Anthony Jones
  • FUSOSOME COMPOSITIONS AND USES THEREOF
    Publication number: 20210198698
    Abstract: The present disclosure provides, at least in part, methods and compositions for in vivo fusosome delivery. In some embodiments, the fusosome comprises a combination of elements that promote specificity for target cells, e.g., one or more of a fusogen, a positive target cell-specific regulatory element, and a non-target cell-specific regulatory element. In some embodiments, the fusosome comprises one or more modifications that decrease an immune response against the fusosome.
    Type: Application
    Filed: July 9, 2019
    Publication date: July 1, 2021
    Inventors: Geoffrey A. von Maltzahn, Jacob Rosenblum Rubens, John Miles Milwid, Michael Travis Mee, Neal Francis Gordon, Jagesh Vijaykumar Shah
  • CYTOBIOLOGICS AND THERAPEUTIC USES THEREOF
    Publication number: 20210187018
    Abstract: This disclosure provides, e.g., cytobiologic compositions and methods of use thereof. The cytobiologics can be used, e.g., to deliver a protein or nucleic acid to a target cell.
    Type: Application
    Filed: December 7, 2018
    Publication date: June 24, 2021
    Applicant: FLAGSHIP PIONEERING INNOVATIONS V, INC.
    Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael Travis Mee, Nathan Wilson Stebbins, Molly Krisann Gibson, Neal Francis Gordon, Bo Zhang, Kyle Marvin Trudeau, Brigham Jay Hartley, Tamar Rose Putiri, Kiana Mahdaviani, Jagesh Vijaykumar Shah, Michael Connor, Peter Anthony Jones
  • COMPOSITIONS AND METHODS FOR MEMBRANE PROTEIN DELIVERY
    Publication number: 20210137839
    Abstract: Fusosome compositions and methods are described herein.
    Type: Application
    Filed: February 15, 2019
    Publication date: May 13, 2021
    Inventors: Geoffrey A. von Maltzahn, John Miles Milwid, Jacob Rosenblum Rubens, Michael Travis Mee, Neal Francis Gordon, Jagesh Vijaykumar Shah, Kyle Marvin Trudeau, Brigham Jay Hartley