Patents by Inventor Jahangir Igbal

Jahangir Igbal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating hyperlipidemias
    Patent number: 8455523
    Abstract: The present invention is directed to a composition and method for the treatment of hyperlipidemias by targeting Microsomal triglyceride transfer protein (MTP). In particular, the present invention is directed to a combination of at least one MTP inhibitor and at least one lipid-lowering agent, both in an amount effective to treat hyperlipidemias.
    Type: Grant
    Filed: January 7, 2011
    Date of Patent: June 4, 2013
    Assignee: The Research Foundation of State University of New York
    Inventors: M. Mahmood Hussain, Jahangir Igbal, Joby Josekutty
  • Compositions and methods for treating hyperlipidemias
    Publication number: 20120029028
    Abstract: The present invention is directed to a composition and method for the treatment of hyperlipidemias by targeting Microsomal triglyceride transfer protein (MTP). In particular, the present invention is directed to a combination of at least one MTP inhibitor and at least one lipid-lowering agent, both in an amount effective to treat hyperlipidemias.
    Type: Application
    Filed: January 7, 2011
    Publication date: February 2, 2012
    Applicant: The Research Foundation of State University of New York
    Inventors: M. Mahmood Hussain, Jahangir Igbal, Joby Josekutty
  • Fluoresence assay for mtp activity
    Publication number: 20060228764
    Abstract: The present invention is directed to methods for assaying microsomal triglyceride transfer protein (MTP) which are amenable to automation and high-throughput screening. The assays may be used to measure MTP activity in cell and tissue homogenates as well as purified MTP. The methods provided by the present invention have the advantages of ease, rapidity, sensitivity, avoidance of the use of negatively charged lipids, versatility in studying different lipid transfer activities by purified and cellular MTP and the ability to measure inhibitory activity. In addition, methods of identifying compounds that modulate the lipid transfer activity of MTP are provided.
    Type: Application
    Filed: June 25, 2004
    Publication date: October 12, 2006
    Inventors: M. Hussain, Humra Athar, Jahangir Igbal