Patents by Inventor Jaime E. Ramirez-Vick

Jaime E. Ramirez-Vick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hybridization of target DNA with immobilized nucleic acid analogs
    Patent number: 7270954
    Abstract: This invention is related to the immobilization of peptide nucleic acids (PNAs) onto solid surfaces for use in hybridization, purification, biosensing, and other biochemical applications. Specifically, their use to increase the thermal stability, specificity, and lifetime of devices based on in situ hybridization is disclosed. A method is disclosed by which peptide nucleic acids replace oligonucleotides as probes in the detection of specific DNA and RNA sequences.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: September 18, 2007
    Assignee: Iris Biotechnologies, Inc.
    Inventor: Jaime E. Ramirez-Vick
  • Reversible binding of molecules to metal substrates through affinity interactions
    Patent number: 7108971
    Abstract: This invention is related to methods for the immobilization of labeled ligands on solid surfaces using soft metal-soft base bonding. The ligand-binding solid surface comprises a soft metal solid support and a heterobifunctional spacer chemi- or physisorbed to said soft metal solid support via soft metal-soft base bonding.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: September 19, 2006
    Assignee: Iris Biotechnologies, Inc.
    Inventor: Jaime E. Ramirez-Vick
  • Magnetic field enhanced hybridization of target molecules to immobilized probes
    Patent number: 6852493
    Abstract: The invention provides a method for increasing the hybridization rate of nucleic acids in a nucleic acid assay by labeling nucleic acid molecules with paramagnetic labels and activating a magnetic field inducing rapid migration of the labeled molecules to a solid support, where the labeled molecule hybridizes with its complementary pair. The paramagnetic label may be present on the target nucleic acid or the probe nucleic acid, depending upon whether the target or probe are the immobile phase.
    Type: Grant
    Filed: November 19, 2001
    Date of Patent: February 8, 2005
    Assignee: Iris Biotechnologies, Inc.
    Inventors: Jaime E. Ramirez-Vick, Simon Chin
  • Reversible binding of molecules to metal substrates through affinity interactions
    Publication number: 20040091858
    Abstract: This invention is related to methods for the immobilization of labeled ligands on solid surfaces using soft metal-soft base bonding. The ligand-binding solid surface comprises a soft metal solid support and a heterobifunctional spacer chemi- or physisorbed to said soft metal solid support via soft metal-soft base bonding.
    Type: Application
    Filed: December 19, 2001
    Publication date: May 13, 2004
    Inventor: Jaime E. Ramirez-Vick
  • Magnetic field enhanced hybridization of target molecules to immobilized probes
    Publication number: 20020164607
    Abstract: The invention provides a method for increasing the hybridization rate of nucleic acids in a nucleic acid assay by labeling nucleic acid molecules with paramagnetic labels and activating a magnetic field inducing rapid migration of the labeled molecules to a solid support, where the labeled molecule hybridizes with its complementary pair. The paramagnetic label may be present on the target nucleic acid or the probe nucleic acid, depending upon whether the target or probe are the immobile phase.
    Type: Application
    Filed: November 19, 2001
    Publication date: November 7, 2002
    Inventors: Jaime E. Ramirez-Vick, Simon Chin
  • Reversible binding of molecules to metal substrates through affinity interactions
    Publication number: 20020160391
    Abstract: This invention is related to methods for the immobilization of labeled ligands on solid surfaces using soft metal-soft base bonding. The ligand-binding solid surface comprises a soft metal solid support and a heterobifunctional spacer chemi- or physisorbed to said soft metal solid support via soft metal-soft base bonding.
    Type: Application
    Filed: December 19, 2001
    Publication date: October 31, 2002
    Inventor: Jaime E. Ramirez-Vick