Patents by Inventor Jaime Modiano

Jaime Modiano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of tumor Fas expression to determine response to anti-cancer therapy
    Patent number: 10352936
    Abstract: The invention provides methods for using expression levels of Fas to select individuals or subpopulation of individuals who can benefit from an anti-cancer therapy and for assessing whether an individual suspected of having or developing cancerous tumors will beneficially respond to an anticancer therapy. The invention additionally provides methods of treatment for individuals selected as likely to benefit from anti-cancer therapy based on Fas expression levels.
    Type: Grant
    Filed: April 13, 2012
    Date of Patent: July 16, 2019
    Assignee: ApopLogic Pharmaceuticals, Inc.
    Inventors: Jaime Modiano, Donald Bellgrau, Richard C. Duke
  • CANCER-ASSOCIATED GERM-LINE AND SOMATIC MARKERS AND USES THEREOF
    Publication number: 20150299795
    Abstract: The invention provides methods and compositions for identifying subjects, including canine subjects, having an elevated risk of developing cancer or having an undiagnosed cancer. These subjects are identified based on the presence of germ-line allele(s) and markers and various somatic mutations.
    Type: Application
    Filed: May 30, 2013
    Publication date: October 22, 2015
    Applicants: The Broad Institute, Inc., Trustees of Tufts College, North Carolina State University, Regents of the University of Minnesota
    Inventors: Kerstin Lindblad-Toh, Noriko Tonomura, Evan Mauceli, Jaime Modiano, Matthew Breen
  • USE OF TUMOR FAS EXPRESSION TO DETERMINE RESPONSE TO ANTI-CANCER THERAPY
    Publication number: 20140294754
    Abstract: The invention provides methods for using expression levels of Fas to select individuals or subpopulation of individuals who can benefit from an anti-cancer therapy and for assessing whether an individual suspected of having or developing cancerous tumors will beneficially respond to an anticancer therapy. The invention additionally provides methods of treatment for individuals selected as likely to benefit from anti-cancer therapy based on Fas expression levels.
    Type: Application
    Filed: April 13, 2012
    Publication date: October 2, 2014
    Inventors: Jaime Modiano, Donald Bellgrau, Richard C. Duke
  • Early Detection of Hemangiosarcoma and Angiosarcoma
    Publication number: 20080050730
    Abstract: A variety of methods, compositions and kits are provided for the early detection, diagnosis and treatment of hemangiosarcoma in dogs and angiosarcomas in humans.
    Type: Application
    Filed: September 9, 2005
    Publication date: February 28, 2008
    Applicant: Regents of the University of Colorado
    Inventors: Jaime Modiano, Stuart Helfand