Patents by Inventor Jaime VAQUER-ALICEA

Jaime VAQUER-ALICEA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TAU BIOSENSOR CELL LINES
    Publication number: 20240043483
    Abstract: The present disclosure provides biosensor cells and methods of use thereof. The disclosure provides, for example, methods of measuring a titer of or of detecting a seed tau protein in a sample, methods of detecting Alzheimer's disease (AD), or a neurodegenerative tauopathy disease or condition linked to tau protein aggregation, and methods for the identification of putative tau protein aggregation inhibitors or modulators.
    Type: Application
    Filed: December 21, 2021
    Publication date: February 8, 2024
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Marc DIAMOND, Victor MANON, Jaime VAQUER-ALICEA, Brian HITT
  • TDP-43 BIOSENSOR CELL LINES
    Publication number: 20230288432
    Abstract: The present disclosure provides methods for the identification, characterization and ranking of putative tau monomer stabilizing agents. Specifically, the disclosure provides methods for assessing the capability of a test compound to stabilize a tau monomer, methods of prioritizing a plurality of test compounds from a library identified as tau monomer stabilizing agents, methods of screening a test compound library to identify tau monomer stabilizing agents, and a kit providing the reagents to perform the described methods.
    Type: Application
    Filed: July 2, 2021
    Publication date: September 14, 2023
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Marc I. DIAMOND, Jaime VAQUER-ALICEA, Gianna C. MAGGIORE
  • TAU PEPTIDE ANTIGENS AND ANTIBODIES BINDING THERETO FOR THE TREATMENT OF TAUOPATHIES
    Publication number: 20220273779
    Abstract: The disclosure provides methods and compositions for treating and diagnosing tauopathies. More specifically, the disclosure relates to the identification of epitopes on tau and their use as vaccines or as reagents to generate monoclonal antibodies that can be used for both diagnosis and treatment of tau-related diseases.
    Type: Application
    Filed: November 18, 2019
    Publication date: September 1, 2022
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Marc I. DIAMOND, Kenneth DROMBOSKY, Dailu CHEN, Victor MANON, Xiaohua LIU, Hamid MIRZAEI, Jaime VAQUER-ALICEA, Hilda MIRBAHA, Lukasz A. JOACHIMIAK