Patents by Inventor Jaishree Trikha
Jaishree Trikha has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10794913Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: GrantFiled: March 4, 2019Date of Patent: October 6, 2020Assignee: CYTONOME/ST, LLCInventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Publication number: 20190195876Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: ApplicationFiled: March 4, 2019Publication date: June 27, 2019Inventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Patent number: 10222378Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: GrantFiled: November 20, 2017Date of Patent: March 5, 2019Assignee: CYTONOME/ST, LLCInventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Publication number: 20180074060Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: ApplicationFiled: November 20, 2017Publication date: March 15, 2018Inventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Patent number: 9823252Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: GrantFiled: February 13, 2014Date of Patent: November 21, 2017Assignee: CYTONOME/ST, LLCInventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Publication number: 20140170673Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: ApplicationFiled: February 13, 2014Publication date: June 19, 2014Applicant: CYTONOME/ST, LLCInventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Patent number: 8679422Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: GrantFiled: September 22, 2011Date of Patent: March 25, 2014Assignee: Cytonome/ST, LLCInventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Patent number: 8277764Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: GrantFiled: December 5, 2005Date of Patent: October 2, 2012Assignee: Cytonome/ST, LLCInventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Publication number: 20120009619Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: ApplicationFiled: September 22, 2011Publication date: January 12, 2012Applicant: CYTONOME/ST, LLCInventors: John R. Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Publication number: 20090291463Abstract: A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system. The microfluidic element may comprise a matrix having an affinity for selected molecules in a sample. The matrix binds, reacts with and/or retains the selected molecules without affecting other molecules in the sample.Type: ApplicationFiled: March 27, 2009Publication date: November 26, 2009Applicant: Cytonome, Inc.Inventors: John R. Gilbert, Manish Deshpande, Jaishree Trikha
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Patent number: 7514000Abstract: A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system. The microfluidic element may comprise a matrix having an affinity for selected molecules in a sample. The matrix binds, reacts with and/or retains the selected molecules without affecting other molecules in the sample.Type: GrantFiled: June 30, 2006Date of Patent: April 7, 2009Assignee: Cytonome, Inc.Inventors: John R. Gilbert, Manish Deshpande, Jaishree Trikha
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Publication number: 20070075010Abstract: A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system. The microfluidic element may comprise a matrix having an affinity for selected molecules in a sample. The matrix binds, reacts with and/or retains the selected molecules without affecting other molecules in the sample.Type: ApplicationFiled: June 30, 2006Publication date: April 5, 2007Applicant: Cytonome, Inc.Inventors: John Gilbert, Manish Deshpande, Jaishree Trikha
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Publication number: 20070054408Abstract: A two-pin liquid handling system for crystallizing biomolecules comprises a pair of interacting pins for holding a droplet of liquid therebetween. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The two-pin liquid handling system includes a temperature and humidity control element for controlling the temperature of the sample acquisition region to cause transpiration of water to and from a droplet of biomolecule solution to promote crystallization of the biomolecule.Type: ApplicationFiled: November 10, 2006Publication date: March 8, 2007Applicant: Cytonome, Inc.Inventors: John Gilbert, Jaishree Trikha
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Patent number: 7153699Abstract: A two-pin liquid handling system for crystallizing biomolecules comprises a pair of interacting pins for holding a droplet of liquid therebetween. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The two-pin liquid handling system includes a temperature and humidity control element for controlling the temperature of the sample acquisition region to cause transpiration of water to and from a droplet of biomolecule solution to promote crystallization of the biomolecule.Type: GrantFiled: December 23, 2002Date of Patent: December 26, 2006Assignee: Cytonome, Inc.Inventors: John Gilbert, Jaishree Trikha
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Publication number: 20060269446Abstract: A single disposable cartridge for performing a process on a particle, such as particle sorting, encapsulates all fluid contact surfaces in the cartridge for use with microfluidic particle processing technology. The cartridge interfaces with an operating system for effecting particle processing. The encapsulation of the fluid contact surfaces insures, improves or promotes operator isolation and/or product isolation. The cartridge may employ any suitable technique for processing particles.Type: ApplicationFiled: December 5, 2005Publication date: November 30, 2006Applicant: Cytonome, Inc.Inventors: John Gilbert, Hugh Lewis, Derek Beaupre, Jaishree Trikha, Manish Deshpande
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Patent number: 7094345Abstract: A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system. The microfluidic element may comprise a matrix having an affinity for selected molecules in a sample. The matrix binds, reacts with and/or retains the selected molecules without affecting other molecules in the sample.Type: GrantFiled: March 31, 2004Date of Patent: August 22, 2006Assignee: Cytonome, Inc.Inventors: John R. Gilbert, Manish Deshpande, Jaishree Trikha
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Publication number: 20050112774Abstract: A system for crystallizing a protein and other biomolecules comprises a flow channel for conveying a solution containing the biomolecule to be crystallized and one or more substations related to the crystallization process formed along the flow channel. The system operates by flowing a biomolecule solution through a the flow channel, then performing dialysis on a micro-scale to set crystallization conditions. After dialysis, the concentration of the biomolecule solution is changed by removing water or solvent from the biomolecule solution to promote formation of crystals in a segment of the flow channel. Formed crystals may be observed and harvested from the flow channel.Type: ApplicationFiled: October 25, 2004Publication date: May 26, 2005Inventors: John Gilbert, Jaishree Trikha
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Patent number: 6849459Abstract: A system for crystallizing a protein and other biomolecules comprises a flow channel for conveying a solution containing the biomolecule to be crystallized and one or more substations related to the crystallization process formed along the flow channel. The system operates by flowing a biomolecule solution through a the flow channel, then performing dialysis on a micro-scale to set crystallization conditions. After dialysis, the concentration of the biomolecule solution is changed by removing water or solvent from the biomolecule solution to promote formation of crystals in a segment of the flow channel. Formed crystals may be observed and harvested from the flow channel.Type: GrantFiled: December 23, 2002Date of Patent: February 1, 2005Assignee: Cytonome, Inc.Inventors: John Gilbert, Jaishree Trikha
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Publication number: 20040245102Abstract: A system and method for integrating microfluidic components in a microfluidic system enables the microfluidic system to perform a selected microfluidic function. A capping module includes a microfluidic element for performing a microfluidic function. The capping module is stacked on a microfluidic substrate having microfluidic plumbing to incorporate the microfluidic function into the system. The microfluidic element may comprise a matrix having an affinity for selected molecules in a sample. The matrix binds, reacts with and/or retains the selected molecules without affecting other molecules in the sample.Type: ApplicationFiled: March 31, 2004Publication date: December 9, 2004Inventors: John R. Gilbert, Manish Deshpande, Jaishree Trikha
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Publication number: 20040048388Abstract: A system for crystallizing a protein and other biomolecules comprises a flow channel for conveying a solution containing the biomolecule to be crystallized and one or more substations related to the crystallization process formed along the flow channel. The system operates by flowing a biomolecule solution through a the flow channel, then performing dialysis on a micro-scale to set crystallization conditions. After dialysis, the concentration of the biomolecule solution is changed by removing water or solvent from the biomolecule solution to promote formation of crystals in a segment of the flow channel. Formed crystals may be observed and harvested from the flow channel.Type: ApplicationFiled: December 23, 2002Publication date: March 11, 2004Applicant: Teragenics, Inc.Inventors: John Gilbert, Jaishree Trikha