Abstract: There is provided a magnesium phosphate gel comprising water as a dispersing phase and phosphate ions (PO43?), a divalent cation, and sodium ions (Na+), wherein the divalent cation is magnesium (Mg2+) or a mixture of magnesium and calcium (Ca2+), the mixture comprising up to 30% by weight of calcium based on the total weight of the mixture. Methods of making and manufacturing this gel are also provided.

Abstract: Discloses are stabilized calcium pyrophosphate nanotubes, a process for making calcium pyrophosphate nanotubes comprising agitating at less than 2 OkHz an aqueous suspension of a calcium and a phosphate for a time sufficient to precipitate said inorganic calcium pyrophosphate nanotubes, and uses thereof.

Abstract: Disclosed herein is a matrix for inducing or enhancing osteoclast differentiation. The matrix comprises a material having an osteoclastogenic agent associated therewith, the agent being releasable from the material in an amount which is sufficient to induce or enhance osteoclast differentiation.

Abstract: Disclosed herein is an implant for use in stimulating tissue growth. The implant comprises a body with a body core and a body surface. The body is made from a non-hydrogel polymer material. A tissue growth stimulating material is disposed within the body core or deposited onto the body surface, in an amount which is sufficient to stimulate tissue growth within the body core or adjacent to the body surface. Also disclosed are implant bodies made from ceramic, metallic materials, and non-copper containing hydrogels.

Abstract: In a first aspect, the present invention discloses a self setting calcium phosphate cement comprising:—(i) a powdered component, said powdered component having an average particle size d50 of less than 15 ?m, and (ii) a calcium phosphate based powder, said powder having an average particle size d50 greater than that of the powdered component, said powdered component and said calcium phosphate based powder being suspended in water containing a dissolved zeta potential increasing additive in sufficient quantity to increase the zeta potential of the suspended particles to at least 30 mV, and wherein the zeta potential increasing additive is chosen to be compatible with the setting pH of the same calcium phosphate cement without the zeta potential increasing additive.

Abstract: In a first aspect, the present invention discloses a self setting calcium phosphate cement comprising:—(i) a powdered component, said powdered component having an average particle size d50 of less than 15 ?m, and (ii) a calcium phosphate based powder, said powder having an average particle size d50 greater than that of the powdered component, said powdered component and said calcium phosphate based powder being suspended in water containing a dissolved zeta potential increasing additive in sufficient quantity to increase the zeta potential of the suspended particles to at least 30 mV, and wherein the zeta potential increasing additive is chosen to be compatible with the setting pH of the same calcium phosphate cement without the zeta potential increasing additive.

Abstract: The invention relates to bone cement compositions comprising a calcium component and a liquid component in which the liquid component comprises pyrophosphate ions with either orthophosphate ions or water, or with both orthophosphate ions and water.

Abstract: In a first aspect, the present invention discloses a self setting calcium phosphate cement comprising:—(i) a powdered component, said powdered component having an average particle size d50 of less than 15 ?m, and (ii) a calcium phosphate based powder, said powder having an average particle size d50 greater than that of the powdered component, said powdered component and said calcium phosphate based powder being suspended in water containing a dissolved zeta potential increasing additive in sufficient quantity to increase the zeta potential of the suspended particles to at least 30 mV, and wherein the zeta potential increasing additive is chosen to be compatible with the setting pH of the same calcium phosphate cement without the zeta potential increasing additive.