Patents by Inventor Jake GOODWIN-TINDALL
Jake GOODWIN-TINDALL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230265079Abstract: Inhibition of indoleamine 2,3-dioxygenase (IDO1) is an attractive immunotherapeutic approach for the treatment of a variety of cancers. Dysregulation of this enzyme has also been implicated in other severe diseases such as Alzheimer's disease and arthritis. Small molecule inhibitors of IDO, syntheses, and uses thereof are provided.Type: ApplicationFiled: January 12, 2023Publication date: August 24, 2023Inventors: Donald WEAVER, Michael G. BRANT, Stephanie WOHNIG, Fan WU, Jake GOODWIN-TINDALL, Autumn MEEK, Paolo SCHIAVINI
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Patent number: 11608323Abstract: The invention relates to pyrrolone compounds of the formula (I) wherein X, R1, R2, R3, Ra, Rb, Rc and Rd are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.Type: GrantFiled: December 17, 2018Date of Patent: March 21, 2023Assignees: SYNGENTA PARTICIPATIONS AG, SYNGENTA LIMITEDInventors: James Alan Morris, Jutta Elisabeth Boehmer, Ravindra Sonawane, Timothy Robert Desson, Sally Elizabeth Russell, Kenneth Ling, Alan Joseph Hennessy, Matthew Brian Hotson, Adrian Longstaff, Sr., Mangala Phadte, Claire Janet Russell, Jake Goodwin-Tindall
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Patent number: 11572354Abstract: Inhibition of indoleamine 2,3-dioxygenase (IDO1) is an attractive immunotherapeutic approach for the treatment of a variety of cancers. Dysregulation of this enzyme has also been implicated in other severe diseases such as Alzheimer's disease and arthritis. Small molecule inhibitors of Formula (Ia) and (Ib) of IDO, their synthesis, and uses thereof are provided.Type: GrantFiled: January 9, 2019Date of Patent: February 7, 2023Assignee: University Health NetworkInventors: Donald Weaver, Michael G. Brant, Stephanie Wohnig, Fan Wu, Jake Goodwin-Tindall, Autumn Meek, Paolo Schiavini
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Publication number: 20210053942Abstract: Inhibition of indoleamine 2,3-dioxygenase (IDO1) is an attractive immunotherapeutic approach for the treatment of a variety of cancers. Dysregulation of this enzyme has also been implicated in other severe diseases such as Alzheimer's disease and arthritis. Small molecule inhibitors of Formula (Ia) and (Ib) of IDO, their synthesis, and uses thereof are provided.Type: ApplicationFiled: January 9, 2019Publication date: February 25, 2021Inventors: Donald WEAVER, Michael G. BRANT, Stephanie WOHNIG, Fan WU, Jake GOODWIN-TINDALL, Autumn MEEK, Paulo SCHIAVINI
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Publication number: 20190112288Abstract: The invention relates to pyrrolone compounds of the formula (I) wherein X, R1, R2, R3, Ra, Rb, Rc and Rd are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.Type: ApplicationFiled: December 17, 2018Publication date: April 18, 2019Applicant: SYNGENTA PARTICIPATIONS AGInventors: James Alan MORRIS, Jutta Elisabeth BOEHMER, Ravindra SONAWANE, Timothy Robert Desson, Sally Elizabeth Russell, Kenneth Ling, Alan Joseph Hennessy, Matthew Brian Hotson, Adrian Longstaff, SR., Mangala Phadte, Claire Janet Russell, Jake GOODWIN-TINDALL
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Patent number: 9751865Abstract: The invention relates to substituted dihydro-hydantoin derivatives of the formula (I) wherein X, Ra, Rb, Rc, R1, R2 and R3 are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds 10 to control or inhibit plant growth.Type: GrantFiled: December 17, 2014Date of Patent: September 5, 2017Assignee: Syngenta LimitedInventors: James Alan Morris, Ravindra Sonawane, Mangala Phadte, Jake Goodwin-Tindall, Jutta Elisabeth Boehmer, Timothy Robert Desson, Claire Janet Russell, Alan Joseph Hennessy, Matthew Brian Hotson
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Publication number: 20170121319Abstract: The invention relates to dihydro-hydantoin compounds of the formula (I) wherein X, Rb, Rc, R2 and R3 are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.Type: ApplicationFiled: June 12, 2015Publication date: May 4, 2017Applicant: Syngenta Participations AGInventors: Alan Joseph HENNESSY, James Alan MORRIS, Mangala PHADTE, Timothy Robert DESSON, Jake GOODWIN-TINDALL, Sally Elizabeth RUSSELL, Jutta Elisabeth BOEHMER, Donn Warwick MOSELEY
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Patent number: 9487502Abstract: The invention relates to pyrrolone compounds of the formula (I) wherein X, R1, R2, R3, Ra, Rc and Rd are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.Type: GrantFiled: August 14, 2014Date of Patent: November 8, 2016Assignees: Syngenta Limited, Syngenta Participations AGInventors: Mangala Phadte, Ravindra Sonaware, James Alan Morris, Alan Joseph Hennessy, Jutta Elisabeth Boehmer, Adrian Longstaff, Timothy Robert Desson, Sally Elizabeth Russell, Matthew Brian Hotson, Donn Warwick Moseley, Claire Janet Russell, Jake Goodwin-Tindall
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Publication number: 20160318906Abstract: The invention relates to substituted dihydro-hydantoin derivatives of the formula (I) wherein X, Ra, Rb, Rc, R1, R2 and R3 are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds 10 to control or inhibit plant growth.Type: ApplicationFiled: December 17, 2014Publication date: November 3, 2016Applicant: Syngenta LimitedInventors: James Alan MORRIS, Ravindra SONAWANE, Mangala PHADTE, Jake GOODWIN-TINDALL, Jutta Elisabeth BOEHMER, Timothy Robert DESSON, Claire Janet RUSSELL, Alan Joseph HENNESSY, Matthew Brian HOTSON
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Publication number: 20160264547Abstract: The invention relates to pyrrolone compounds of the formula (I), wherein X, R1, R2, R3, Ra, Rb, Rc and Rd are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.Type: ApplicationFiled: October 2, 2014Publication date: September 15, 2016Applicant: SYNGENTA PARTICIPATIONS AGInventors: Mangala PHADTE, Ravindra Sonawane, James Alan Morris, Jutta Elisabeth BOEHMER, Timothy Robert DESSON, Sally Elizabeth RUSSELL, Kenneth LING, Alan Joseph Hennessy, Matthew Brian HOTSON, Adrian LONGSTAFF, Clarie Janet RUSSELL, Jake GOODWIN-TINDALL
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Publication number: 20160251332Abstract: The invention relates to dihydro hydantoin compounds of the formula (I) wherein X, R3, Ra, Rb Rc and Rd are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.Type: ApplicationFiled: October 24, 2014Publication date: September 1, 2016Applicant: SYNGENTA PARTICIPATIONS AGInventors: Mangala PHADTE, Ravindra Sonawane, James Alan Morris, Jutta Elisabeth BOEHMER, Timothy Robert DESSON, Alan Joseph Hennessy, Jake GOODWIN-TINDALL
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Publication number: 20160200708Abstract: The invention relates to pyrrolone compounds of the formula (I) wherein X, R1, R2, R3, Ra, Rc and Rd are as defined in the specification. Furthermore, the present invention relates to processes and intermediates for making compounds of formula (I), to herbicidal compositions comprising these compounds and to methods of using these compounds to control plant growth.Type: ApplicationFiled: August 14, 2014Publication date: July 14, 2016Applicants: Syngenta Limited, Syngenta Participations AGInventors: Mangala PHADTE, Ravindra SONAWARE, James Alan MORRIS, Alan Joseph HENNESSY, Jutta Elisabeth BOEHMER, Adrian LONGSTAFF, Timothy Robert DESSON, Sally Elizabeth RUSSELL, Matthew Brian HOTSON, Donn Warwick MOSELEY, Claire Janet RUSSELL, Jake GOODWIN-TINDALL