Patents by Inventor Jakob-Andreas Tschaepe

Jakob-Andreas Tschaepe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Invertebrate animal model with neurodegenerative phenotype for screening and testing substances
    Patent number: 7554003
    Abstract: The present invention claims an invertebrate animal that has been modified to express a set of genes, the set comprising the gene coding for a modified version of the gamma subunit of AMP-activated protein kinase (AMPKg). According to the invention, the animal displays an identifiable phenotype related to lipid metabolism and neurodegeneration. This animal provides a model of neurodegenerative diseases, particularly Alzheimer's disease, and may be useful for screening and testing modulating agents, substances and therapeutic compounds for neurodegenerative disorders.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: June 30, 2009
    Assignee: Evotec Neurosciences GmbH
    Inventors: Doris Kretschmar, Jakob-Andreas Tschaepe
  • Invertebrate animal model with neurodegenerative phenotype for screening and testing substances
    Publication number: 20070107070
    Abstract: The present invention claims an invertebrate animal that has been modified to express a set of genes, said set comprising the gene coding for a modified version of the gamma subunit of AMP-activated protein kinase (AMPKg). According to the invention, the animal displays an identifiable phenotype related to lipid metabolism and neurodegeneration. This animal provides a model of neurodegenerative diseases, particularly Alzheimer's disease, and may be useful for screening and testing modulating agents, substances and therapeutic compounds for neurodegenerative disorders.
    Type: Application
    Filed: October 10, 2006
    Publication date: May 10, 2007
    Inventors: Doris Kretzschmar, Jakob-Andreas Tschaepe
  • An invertebrate animal model with neurodegenerative phenotype for screening and testing substances
    Publication number: 20060053499
    Abstract: The present invention claims an invertebrate animal that has been modified to express a set of genes, said set comprising the gene coding for a modified version of the gamma subunit of AMP-activated protein kinase (AMPKg). According to the invention, the animal displays an identifiable phenotype related to lipid metabolism and neurodegeneration. This animal provides a model of neurodegenerative diseases, particularly Alzheimer's disease, and may be useful for screening and testing modulating agents, substances and therapeutic compounds for neurodegenerative disorders.
    Type: Application
    Filed: April 10, 2002
    Publication date: March 9, 2006
    Inventors: Doris Kretzschmar, Jakob-Andreas Tschaepe