Patents by Inventor Jakob FUHRMANN

Jakob FUHRMANN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-(2-(4-CYCLOPROPYL-1H-1,2,3-TRIAZOL-1-YL)ACETYL)-4-HYDROXY-N-(BENZYL)PYRROLIDIN E-2-CARBOXAMIDE DERIVATIVES AS VHL INHIBITORS FOR THE TREATMENT OF ANEMIA AND CANCER
    Publication number: 20230391766
    Abstract: The present disclosure relates to compounds comprising a VHL ligand moiety and to methods of using such compounds as ligands of VHL. The present disclosure further relates to the use of the compounds described herein, or pharmaceutical compositions thereof, to prevent and/or treat a range of diseases, disorders, and conditions.
    Type: Application
    Filed: May 9, 2023
    Publication date: December 7, 2023
    Applicant: Genentech, Inc.
    Inventors: Jakob FUHRMANN, Hao WU, Wayne J. FAIRBROTHER
  • PYRROLIDINE DERIVATIVES AND METHODS OF USE
    Publication number: 20230295145
    Abstract: The present disclosure relates to compounds and pharmaceutical compositions thereof, and methods of using the compounds and compositions in therapy, such as methods of treating cancer.
    Type: Application
    Filed: May 24, 2023
    Publication date: September 21, 2023
    Inventors: Jakob Fuhrmann, Nicholas John Skelton, Peter Scott Dragovich
  • 1-(2-(4-CYCLOPROPYL-1H-1,2,3-TRIAZOL-1-YL)ACETYL)-4-HYDROXYPYRROLIDINE-2-CARBOXA|MIDE DERIVATIVES AS VHL INHIBITORS FOR THE TREATMENT OF ANEMIA
    Publication number: 20230271944
    Abstract: The present disclosure relates to compounds comprising a VHL ligand moiety and to methods of using such compounds as ligands of VHL. The present disclosure further relates to the use of the compounds described herein, or pharmaceutical compositions thereof, to prevent and/or treat a range of diseases, disorders, and conditions.
    Type: Application
    Filed: May 9, 2023
    Publication date: August 31, 2023
    Applicant: Genentech, Inc.
    Inventors: Jakob FUHRMANN, Hao WU, Wayne J. FAIRBROTHER
  • MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20220106361
    Abstract: Provided, inter alia, are macrocyclic compounds.
    Type: Application
    Filed: June 22, 2021
    Publication date: April 7, 2022
    Applicant: Genentech, Inc.
    Inventors: Jakob FUHRMANN, Wayne FAIRBROTHER, Hao WU, Jeremy MURRAY