Patents by Inventor Jakob Loven

Jakob Loven has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND SYSTEMS FOR EVALUATING GENES
    Publication number: 20160032387
    Abstract: Aspects and embodiments disclosed herein are directed to providing methods and systems for evaluating target genes and/or associated super enhancers and or super-enhance components. In some embodiments, the method includes selecting a gene associated with a super-enhancer, to provide a selected gene, evaluating the selected gene for contribution to a cell state, e.g., a state characterized by a disease or disorder (a disease/disorder state), and responsive to the evaluation, classifying the selected gene and/or associated super-enhancer.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Christian C. Fritz, David A. Orlando, Matthew G. Guenther, Jakob Loven, Peter B. Rahl, Charles Y. Lin
  • Super-enhancers and methods of use thereof
    Patent number: 9181580
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Grant
    Filed: October 24, 2014
    Date of Patent: November 10, 2015
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Richard A. Young, Warren Whyte, Denes Hnisz, Jakob Loven, Heather Hoke, David Orlando, Charles Y. Lin, Tony Lee
  • SUPER-ENHANCERS AND METHODS OF USE THEREOF
    Publication number: 20150111761
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Application
    Filed: October 24, 2014
    Publication date: April 23, 2015
    Inventors: Richard A. Young, Warren Whyte, Denes Hnisz, Jakob Loven, Heather Hoke, David Orlando, Charles Y. Lin, Tony Lee
  • SUPER-ENHANCERS AND METHODS OF USE THEREOF
    Publication number: 20140296218
    Abstract: The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer).
    Type: Application
    Filed: October 25, 2013
    Publication date: October 2, 2014
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Richard A. Young, Warren Whyte, Denes Hnisz, Jakob Loven, Heather Hoke, David Orlando, Charles Y. Lin, Tony Lee