Patents by Inventor Jakub Golab

Jakub Golab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them, and their use as inhibitors of the thioredoxin—thioredoxin reductase system
    Patent number: 9018255
    Abstract: The subject of the present invention are novel esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them and their use in the production of drugs for the prophylaxis or treatment of oncogenic diseases and diseases connected with increased cell proliferation.
    Type: Grant
    Filed: October 16, 2011
    Date of Patent: April 28, 2015
    Assignees: Instytut Chemii Organicznej Polskiej Akademii Nauk, Warszawski Uniwersytet Medyczny
    Inventors: Ryszard Ostaszewski, Szymon Klossowski, Izabela Ziuzia, Angelika Szokalska, Marta Swiech, Jakub Golab
  • Novel Esters of (Acyloxymethyl)Acrylamide, a Pharmaceutical Composition Containing Them, and Their use as Inhibitors of the Thioredoxin - Thioredoxin Reductase System
    Publication number: 20130317102
    Abstract: The subject of the present invention are novel esters of (acyloxymethyl)acrylamide, a pharmaceutical composition containing them and their use in the production of drugs for the prophylaxis or treatment of oncogenic diseases and diseases connected with increased cell proliferation.
    Type: Application
    Filed: October 16, 2011
    Publication date: November 28, 2013
    Inventors: Ryszard Ostaszewski, Szymon Klossowski, Izabela Ziuzia, Angelika Szokalska, Marta Swiech, Jakub Golab
  • NOVEL ANTIBODY THERAPIES
    Publication number: 20110091473
    Abstract: Antibody capable of mediating effector function which specifically binds to a multiple membrane spanning antigen or to an antigen which forms dimers or multimers (i) for use in combination with a cholesterol-increasing agent in the treatment of a disease or disorder associated with said antigen, wherein antibody-induced effector function has a beneficial effect on said disease or disorder or (ii) for use in the treatment of such disease or disorder, wherein the antibody is to be administered to a subject undergoing therapy with a cholesterol-lowering agent, such as a statin, and wherein the subject is withdrawn from treatment with the cholesterol-lowering agent prior to the administration of the antibody. Furthermore, a kit of parts comprising such antibody as well as a cholesterol-increasing agent.
    Type: Application
    Filed: October 22, 2008
    Publication date: April 21, 2011
    Applicant: GENMAB A/S
    Inventors: Jakub Golab, Magdalena Winiarska, Paul Parren, Wendy Mackus, Patrick Engelberts