Patents by Inventor Jamal Christo Tarazi

Jamal Christo Tarazi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF A PD-1 ANTAGONIST AND A VEGFR INHIBITOR FOR TREATING CANCER
    Publication number: 20220324979
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L1.
    Type: Application
    Filed: April 20, 2022
    Publication date: October 13, 2022
    Applicants: PFIZER INC., MERCK SHARP & DOHME CORP.
    Inventors: Jean-Francois Andre MARTINI, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro
  • COMBINATION OF A PD-1 ANTAGONIST AND A VEGFR INHIBITOR FOR TREATING CANCER
    Publication number: 20200325228
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L 1.
    Type: Application
    Filed: January 14, 2020
    Publication date: October 15, 2020
    Applicants: PFIZER INC., MERCK SHARPE & DOHME CORP.
    Inventors: Jean-Francois Andre Martini, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro
  • Combination of a PD-1 antagonist and a VEGFR inhibitor for treating cancer
    Patent number: 10570202
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L1.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: February 25, 2020
    Assignees: Pfizer Inc., Merck Sharpe & Dohme Corp.
    Inventors: Jean-Francois Andre Martini, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro
  • CANCER TREATMENT
    Publication number: 20190331687
    Abstract: Diagnostic methods for predicting whether a human tumor is sensitive to treatment with axitinib, and methods of treating a human tumor are disclosed. The methods are based on measurement of CD68 polypeptide expression levels in a tissue sample from a tumor. CD68 expression levels can be measured using immunohistochemistry, where the percentage of CD68-positive cells and density of CD68-positive cells within the tumor can be determined.
    Type: Application
    Filed: March 1, 2019
    Publication date: October 31, 2019
    Applicant: PFIZER INC.
    Inventors: Jean-François André MARTINI, Jamal Christo TARAZI, James Andrew WILLIAMS
  • CANCER TREATMENT
    Publication number: 20170184602
    Abstract: Diagnostic methods for predicting whether a human tumor is sensitive to treatment with axitinib, and methods of treating a human tumor are disclosed. The methods are based on measurement of CD68 polypeptide expression levels in a tissue sample from a tumor. CD68 expression levels can be measured using immunohistochemistry, where the percentage of CD68-positive cells and density of CD68-positive cells within the tumor can be determined.
    Type: Application
    Filed: April 16, 2015
    Publication date: June 29, 2017
    Applicant: PFIZER INC.
    Inventors: Jean-François André MARTINI, Jamal Christo TARAZI, James Andrew WILLIAMS
  • COMBINATION OF A PD-1 ANTAGONIST AND A VEGFR INHIBITOR FOR TREATING CANCER
    Publication number: 20170166641
    Abstract: The present disclosure describes combination therapies comprising an antagonist of Programmed Death 1 receptor (PD-1) and a VEGFR inhibitor, and the use of the combination therapies for the treatment of cancer, and in particular for treating cancers that express PD-L1.
    Type: Application
    Filed: February 3, 2015
    Publication date: June 15, 2017
    Inventors: Jean-Francois Andre Martini, Jamal Christo Tarazi, Rodolfo Fleury Perini, David J. Mauro