Patents by Inventor Jamal SAEH

Jamal SAEH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12329746
    Abstract: A method for treating AR+ breast cancer in a subject comprising administering to the subject an AR agonist (e.g., SARMs such as RAD140), or in combination with one or more therapeutic agents selected from the group consisting of cdk4/6 inhibitors, m-TOR inhibitors, PI3k inhibitors, PARP inhibitors, BCL-2 inhibitors, and MCL-1 inhibitors.
    Type: Grant
    Filed: September 29, 2023
    Date of Patent: June 17, 2025
    Assignee: Ellipses Pharma Ltd
    Inventors: Gary Hattersley, Jamal Saeh, Ziyang Yu, Chris P. Miller, Teeru Bihani
  • Publication number: 20240207234
    Abstract: A method for treating AR+ breast cancer in a subject comprising administering to the subject an AR agonist (e.g., SARMs such as RAD140), or in combination with one or more therapeutic agents selected from the group consisting of cdk4/6 inhibitors, m-TOR inhibitors, PI3k inhibitors, PARP inhibitors, BCL-2 inhibitors, and MCL-1 inhibitors.
    Type: Application
    Filed: September 29, 2023
    Publication date: June 27, 2024
    Inventors: Gary Hattersley, Jamal Saeh, Ziyang Yu, Chris P. Miller, Teeru Bihani
  • Patent number: 11771682
    Abstract: A method for treating AR+ breast cancer in a subject comprising administering to the subject an AR agonist (e.g., SARMs such as RAD140), or in combination with one or more therapeutic agents selected from the group consisting of cdk4/6 inhibitors, m-TOR inhibitors, PI3k inhibitors, PARP inhibitors, BCL-2 inhibitors, and MCL-1 inhibitors.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: October 3, 2023
    Assignee: Ellipses Pharma Ltd.
    Inventors: Gary Hattersley, Jamal Saeh, Ziyang Yu, Chris Miller, Teeru Bihani
  • Publication number: 20230277444
    Abstract: Disclosed are PTHrP analogue formulations for transdermal delivery of a therapeutically effective amount of a PTHrP analogue, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
    Type: Application
    Filed: November 4, 2022
    Publication date: September 7, 2023
    Applicants: Radius Health, Inc., Kindeva Drug Delivery L.P.
    Inventors: Gary Hattersley, Alan Harris, Jamal Saeh, Ehab Hamed, Kenneth Brown, Daniel Dohmeier, Joan Moseman, Ying Zhang, Lisa Dick
  • Publication number: 20210379162
    Abstract: Provided herein are methods for treating osteoporosis and increasing bone mass density, that includes administering once a day, for about 5 minutes, a transdermal patch loaded with about 300 ?g of abaloparatide, and ZnCl2 at a molar ratio of 2.2:1 of ZnCl2:abaloparatide. Also provided are the single-use transdermal patches loaded with about 300 ?g of abaloparatide, and ZnCl2 at a molar ratio of 2.2:1 of ZnCl2:abaloparatide.
    Type: Application
    Filed: August 6, 2021
    Publication date: December 9, 2021
    Applicants: Radius Health, Inc., Kindeva Drug Delivery L.P.
    Inventors: Kenneth Brown, Ehab Hamed, Alan Harris, Gary Hattersley, Joan Moseman, Jamal Saeh, Lisa Dick
  • Publication number: 20210369816
    Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
    Type: Application
    Filed: March 23, 2021
    Publication date: December 2, 2021
    Applicants: Radius Health, Inc., Kindeva Drug Delivery L.P.
    Inventors: Gary Hattersley, Alan Harris, Jamal Saeh, Ehab Hamed, Kenneth Brown, Daniel Dohmeier, Joan Moseman, Ying Zhang, Lisa Dick
  • Patent number: 10980862
    Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
    Type: Grant
    Filed: January 3, 2020
    Date of Patent: April 20, 2021
    Assignees: Radius Health, Inc., Kindeva Drug Delivery L.P.
    Inventors: Gary Hattersley, Alan Harris, Jamal Saeh, Ehab Hamed, Kenneth Brown, Daniel Dohmeier, Joan Moseman, Ying Zhang, Lisa Dick
  • Publication number: 20200171008
    Abstract: A method for treating AR+ breast cancer in a subject comprising administering to the subject an AR agonist (e.g., SARMs such as RAD140), or in combination with one or more therapeutic agents selected from the group consisting of cdk4/6 inhibitors, m-TOR inhibitors, PI3k inhibitors, PARP inhibitors, BCL-2 inhibitors, and MCL-1 inhibitors.
    Type: Application
    Filed: November 26, 2019
    Publication date: June 4, 2020
    Inventors: Gary Hattersley, Jamal Saeh, Ziyang Yu, Chris Miller, Teeru Bihani
  • Publication number: 20200164045
    Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
    Type: Application
    Filed: January 3, 2020
    Publication date: May 28, 2020
    Applicants: Radius Health, Inc., 3M Innovative Properties Company
    Inventors: Gary Hattersley, Alan Harris, Jamal Saeh, Ehab Hamed, Kenneth Brown, Daniel Dohmeier, Joan Moseman, Ying Zhang, Lisa Dick
  • Patent number: 10568937
    Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: February 25, 2020
    Assignees: Radius Health, Inc., 3M Innovative Properties Company
    Inventors: Gary Hattersley, Alan Harris, Jamal Saeh, Ehab Hamed, Kenneth Brown, Daniel Dohmeier, Joan Moseman, Ying Zhang, Lisa Dick
  • Publication number: 20190117739
    Abstract: Disclosed are abaloparatide formulations for transdermal delivery of a therapeutically effective amount of abaloparatide, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
    Type: Application
    Filed: April 6, 2017
    Publication date: April 25, 2019
    Inventors: Gary HATTERSLEY, Alan HARRIS, Jamal SAEH, Ehab HAMED
  • Publication number: 20190091138
    Abstract: Disclosed are PTHrP analogue formulations for transdermal delivery of a therapeutically effective amount of a PTHrP analogue, as well as transdermal patches prepared using these formulations, methods of preparing the disclosed formulations and patches, and methods of using these formulations and patches to treat osteoporosis, osteopenia, osteoarthritis, and/or bone fracture, improve bone mineral density (BMD), improve trabecular bone score (TBS), and treat, prevent, and/or reduce bone fractures.
    Type: Application
    Filed: April 9, 2018
    Publication date: March 28, 2019
    Inventors: Gary HATTERSLEY, Alan HARRIS, Jamal SAEH, Ehab HAMED
  • Publication number: 20170368036
    Abstract: A method for treating AR+ breast cancer in a subject comprising administering to the subject an AR agonist (e.g., SARMs such as RAD140), or in combination with one or more therapeutic agents selected from the group consisting of cdk4/6 inhibitors, m-TOR inhibitors, PI3k inhibitors, PARP inhibitors, BCL-2 inhibitors, and MCL-1 inhibitors.
    Type: Application
    Filed: June 20, 2017
    Publication date: December 28, 2017
    Inventors: Gary HATTERSLEY, Jamal SAEH, Ziyang YU, Chris MILLER, Teeru BIHANI