Abstract: Provided herein are methods of determining loss of heterozygosity in human leukocyte antigen in liquid biopsies and applications thereof in cancer treatment.

Abstract: Systems and methods are provided for allowing users to safely and efficiently conduct repeatable dynamic experiments involving coordinated applications of force, motion, pressure, temperature, flow, dispersion and other physical events via a testing fixture positioned within an imaging environment.

Abstract: Systems and methods are provided for building a product by additive manufacturing and creating hollow volumes without including build supports in the hollow volume for the layers above the hollow volume. An additive manufacturing cell includes a material handling device, a printer a material delivery system and an energy source to feed the sheets, print on the sheets, apply a powder on the printed sheets, build a hollow volume into the sheets and consolidate the sheets into a product with a contiguous structure.

Abstract: Disclosed are Internet-of-Things (IoT) methods, systems, and devices for determining that health monitoring automated biometric data acquisition devices, the networks to which they are connected, and other connected electrical devices are correctly powered, using normal power levels, able to communicate their results over various communications networks, and can notify people and/or systems of a failure of any of these conditions either in real time or on a deferred time basis. Communications to users regarding such failures are controlled using authorization rules, which may be HIPAA-compliant.

Abstract: A LIDAR unit includes a housing defining a cavity. The LIDAR unit further include a plurality of emitters disposed on a circuit board within the cavity. Each of the emitters emits a laser beam along a transmit path. The LIDAR system further includes a first telecentric lens assembly positioned within the cavity and along the transmit path such that the laser beam emitted from each of the plurality of emitters passes through the first telecentric lens assembly. The LIDAR further includes a second telecentric lens assembly positioned within the cavity and along a receive path such that a plurality of reflected laser beams entering the cavity pass through the second telecentric lens assembly. The first telecentric lens assembly and the second telecentric lens assembly each include a field flattening lens and at least one other lens.

Abstract: A method and apparatus for processing documents is provided. The documents may be conveyed to a feeder for feeding documents to a scanner. The scanner scans each document to obtain image data and then discharges the document to one or more output or sort locations. The system may include a skew reduction assembly for reducing skew in the documents as the documents are fed to the scanner. The system may also include elements for improving image quality and reducing document damage while the document is scanned. The system may further include features for improving the stacking of the discharged documents.

Abstract: A distributed analytics system to control an operation of a monitored system, and method of operation thereof, including an architect subsystem and an edge processing device. The edge subsystem includes an edge processing device associated with the monitored system. The architect subsystem is configured to deploy an analytic model to the edge processing device based on characteristics of the monitored system. The edge processing device is configured to receive the analytic model and independently perform predictive and prescriptive analytics on dynamic input data associated with the monitored system, provide control signals to the monitored system according to the predictive and prescriptive analytics, and provide information to the architect subsystem, including monitored system responses to the control signals. The architect subsystem is configured to modify the analytic model to improve system performance of the monitored system.

Abstract: Methods and systems for evacuating lubricant from an area of an axle are described. The lubricant may be evacuated away from one or more clutches during low temperatures so that a clutch may be engaged while having to displace less lubricant to engage the clutch. In one example, an electric machine may be rotated to evacuate lubricant away from the clutch.

Abstract: Aerospace systems, and systems and methods for assembling an aerospace system or another system or structure, are disclosed. A representative system can include a propellant tank with a dome-shaped head; attachment features on the dome-shaped head; and a thrust structure with legs attached to the attachment features. A representative method can include forming shims to be positioned between the legs and the attachment features. The shims can be formed based on digital characterizations of mounting faces on the attachment features within a reference coordinate system. The method can include positioning a drill jig within the reference coordinate system and using the drill jig to make holes in the shims and/or the attachment features for fastening the legs to the attachment features. A drill jig can include plates that are movable relative to each other. At least one of the plates can include a mounting hole pattern.

Abstract: Drill jigs for positioning mounting holes using metrology processes, and associated systems and methods, disclosed. A representative drill jig system for positioning holes to be made in an object can include a drill jig having a plurality of movable plates. The plates can include: a rotatable plate carrying a hole pattern for positioning the holes to be made; a first translatable plate that is translatable along a first axis; a second translatable plate that is translatable along a second axis that is perpendicular to the first axis; and a base plate carrying one or more attachment elements positioned and configured to grasp the object. In some embodiments, the plates are manually movable via one or more adjusters. In some embodiments, the drill jig includes one or more servos for moving one or more of the plates under computer control, such as in a feedback loop using one or more encoders.

Abstract: A method and apparatus for processing documents is provided. The documents may be conveyed to a feeder for feeding documents to a scanner. The scanner scans each document to obtain image data and then discharges the document to one or more output or sort locations. The system may include a skew reduction assembly for reducing skew in the documents as the documents are fed to the scanner. The system may also include elements for improving image quality and reducing document damage while the document is scanned. The system may further include features for improving the stacking of the discharged documents.

Abstract: Disclosed are systems and methods utilizing an infrared probe and discriminating software to rapidly discriminate abnormal tissue processes from normal tissue during surgery, physical examination of in-situ lesions, and in the assessment of biopsy and resected tissue specimens. Examples demonstrate discrimination of cancerous from noncancerous tissues. The discriminating software, i.e. the metrics, algorithms, calibrant spectra, and decision equations, allows tissue to be identified as abnormal or normal using a minimum of infrared (IR) wavelengths in order to be measured rapidly. The probe records IR metrics approximately 1000 times faster than current commercial instruments, i.e. on a timescale fast enough for clinical use. The probe uses a tunable mid-infrared laser with a small set of selected wavelengths that are optimized for detecting the chemical and molecular signatures of tissue specific lesions to include, but not limited to, cancer, preneoplasia, intracellular accumulations (e.g.

Abstract: Embodiments of the instant disclosure relate to portable radio mounting apparatus (PRMA). The PRMA includes a main body, landing pad, antenna element(s), RF connector conductively coupled to the antenna element, retaining element and has “open” and “closed” states. Landing pad laterally extends from the main body and includes the antenna element(s) and a first end pivotably coupled to main body. RF connector is conductively coupled to the antenna element. In the open state, the landing pad is pivoted away from the main body and thereby exposes the retaining element; the retaining element receives a portable radio and thereby demountably secures the portable radio to the main body; and the RF connector demountably and conductively couples to the portable radio. In the close state, landing pad is pivoted towards the main body and wrapped around the portable; and is demountably coupled to the main body.

Abstract: The present invention tracks provenance (people, place, time, permissions, machine characterization and identification) for an off-chain digital asset, provides data verifiability and enforces least privileged access within a single organization or across multiple organizations via a combination of Blockchain and communication agents to enable data assured operations in a normal operating environment and Logistics Under Attack (LUA) environment. The present invention creates data assurance for a digital asset across networks and within environments as it tracks provenance of the digital asset at rest or in motion allowing a data file to move directly from the originator to a customer at the point of use or point of origin to point of use and all points in between in a prescribed or random flow.

Abstract: An electric powertrain includes a first electric motor that has an uninterrupted connection with a drive shaft of a vehicle. The electric powertrain further includes a second electric motor that has an interruptible connection with the drive shaft. In one form, this interruptible connection includes a clutch. The electric powertrain further includes a first gear train in the form of a first planetary gear and a second gear train in the form of a second planetary gear. The first gear train, second gear train, and clutch are arranged downstream from the first electric motor and second electric motor.

Abstract: The present disclosure provides a lighting apparatus generally comprising an LED module having LEDs and a control module to control the LED module. The LED module has pins positioned on an underside thereof to connect to corresponding pins on the upper surface of the LED. The LED module having a passive electrical component whose value can be detected by the control apparatus. In response to said detection, the control apparatus can perform a variety of functions, including configuring the LED module. The lighting apparatus is further comprised of a reflector, the reflector positioned within a central aperture of the control module and surrounding the LEDs. The reflector serves to focus light from the LEDs and can be secured to a diffuser releasably lockable to the lighting apparatus, the diffuser to diffuse the light from the LEDs.

Abstract: A LIDAR system includes a plurality of LIDAR units. Each of the LIDAR units includes a housing defining a cavity. Each of the LIDAR units further includes a plurality of emitters disposed within the cavity. Each of the plurality of emitters is configured to emit a laser beam. The LIDAR system includes a rotating mirror and a retarder. The retarder is configurable in at least a first mode and a second mode to control a polarization state of a plurality of laser beams emitted from each of the plurality of LIDAR units. The LIDAR system includes a polarizing beam splitter positioned relative to the retarder such that the polarizing beam splitter receives a plurality of laser beams exiting the retarder. The polarizing beam is configured to transmit or reflect the plurality of laser beams exiting the retarder based on the polarization state of the laser beams exiting the retarder.

Abstract: A LIDAR assembly is provided. The LIDAR assembly includes a LIDAR unit. The LIDAR unit includes a housing defining a cavity. The LIDAR unit further includes a plurality of emitters disposed within the cavity. Each of the plurality of emitters is configured to emit a laser beam. The LIDAR assembly further includes a switchable mirror. The switchable mirror is positioned relative to the LIDAR unit such that the switchable mirror receives a plurality of laser beams exiting the housing of the LIDAR unit. The switchable mirror is configurable in at least a reflective state to direct the plurality of laser beams along a first path and a transmissive state to direct the plurality of laser beams along a second path that is different than the first path to widen a field of view of the LIDAR unit along a first axis.

Abstract: A polymerisable liquid crystal (LC) compound, a corresponding polymerizable LC material, a polymer film with flat, negative, or positive optical dispersion obtainable from such a material, and the use of the polymerisable LC, polymerisable LC material and/or polymer film in optical, electro optical, electronic, semiconducting, or luminescent components or devices.

Abstract: The present disclosure provides a lighting apparatus generally comprising an LED module having LEDs and a control module to control the LED module. The LED module has pins positioned on an underside thereof to connect to corresponding pins on the upper surface of the LED. The LED module having a passive electrical component whose value can be detected by the control apparatus. In response to said detection, the control apparatus can perform a variety of functions, including configuring the LED module. The lighting apparatus is further comprised of a reflector, the reflector positioned within a central aperture of the control module and surrounding the LEDs. The reflector serves to focus light from the LEDs and can be secured to a diffuser releasably lockable to the lighting apparatus, the diffuser to diffuse the light from the LEDs.