Patents by Inventor James A. Baum

James A. Baum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230018327
    Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
    Type: Application
    Filed: July 26, 2022
    Publication date: January 19, 2023
    Inventors: James A. Baum, Thomas Cerruti, Stainslaw Flasinski, Xiaoran Fu, Arlene R. Howe, Sara Ann Salvador
  • Publication number: 20220356214
    Abstract: The present invent in discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Application
    Filed: May 11, 2022
    Publication date: November 10, 2022
    Inventors: James A. Baum, Artem G. Evdokimov, Farhad Moshiri, Timothy J. Rydel, Eric J. Sturman, Moritz von Rechenberg, Halong Vu, Andrew M. Wollacott, Meiying Zheng
  • Publication number: 20220356215
    Abstract: The present invention discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Application
    Filed: May 11, 2022
    Publication date: November 10, 2022
    Inventors: James A. Baum, Artem G. EVDOKIMOV, Farhad MOSHIRI, Timothy J. RYDEL, Eric J. STURMAN, Moritz von RECHENBERG, Halong VU, Andrew M. WOLLACOTT, Meiying ZHENG
  • Patent number: 11492638
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Grant
    Filed: September 19, 2017
    Date of Patent: November 8, 2022
    Assignee: MONSANTO TECHNOLOGY, LLC
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. LaRosa, Maolong Lu, Tichafa R. I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Publication number: 20220315945
    Abstract: The present invention relates to control of pest infestation by inhibiting one or more biological functions. The invention provides methods and compositions for such control, By feeding one or more recombinant double stranded RNA molecules provided by the invention to the pest, a reduction in pest infestation is obtained through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Application
    Filed: April 26, 2022
    Publication date: October 6, 2022
    Inventors: James A. Baum, Claire A. CaJacob, Pascale Feldman, Gregory R. Heck, Irene Maria Antonia Nooren, Geert Plaetinck, Wendy T. Maddelein, Ty T. Vaughn
  • Patent number: 11459359
    Abstract: The present invention discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: October 4, 2022
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: James A. Baum, Artem G. Evdokimov, Farhad Moshiri, Timothy J. Rydel, Eric J. Sturman, Moritz von Rechenberg, Halong Vu, Andrew M. Wollacott, Meiying Zheng
  • Publication number: 20220306703
    Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
    Type: Application
    Filed: February 14, 2022
    Publication date: September 29, 2022
    Inventors: James A. Baum, Thomas A. Cerruti, Crystal L. Dart, Leigh H. English, Stanislaw Flasinski, Xiaoran Fu, Victor M. Guzov, Arlene R. Howe, Jay P. Morgenstern, James K. Roberts, Sara A. Salvador, Jinling Wang
  • Publication number: 20220281927
    Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 8, 2022
    Inventors: James A. Baum, Thomas A. Cerruti, Crystal L. Dart, Leigh H. English, Stanislaw Flasinski, Xiaoran Fu, Victor M. Guzov, Arlene R. Howe, Jay P. Morgenstern, James K. Roberts, Sara A. Salvador, Jinling Wang
  • Publication number: 20220267793
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Application
    Filed: March 8, 2022
    Publication date: August 25, 2022
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. Larosa, Maolong Lu, Tichafa R. I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Publication number: 20220243221
    Abstract: Pesticidal proteins (FFPP's) are used to produce derivatives (DP's) that are ineffective and disabled relative to conferring toxic properties upon a target pest, yet the ability of the DP to bind to the receptor to which said FFPP binds is unaffected. Such DP's are useful in inhibiting the FFPP from which it was derived when both are fed to a target pest and for comparing receptor binding capability and efficiency relative to different FFPP's from which the DP has been derived, providing for an assessment of different FFPP's relative to each other, and providing uniformity and certainty in combinations of such FFPP's for compositions, including transgenic plants, that can be used to control pest populations susceptible to both FFPP's, creating more durable transgenic plant products, inhibiting the development of resistance to such FFPP's when used in plants commercially, and in providing a durable and viable resistance management strategy for crops using such FFPP combinations.
    Type: Application
    Filed: February 22, 2022
    Publication date: August 4, 2022
    Inventors: James A. Baum, Artem G. Evdokimov, Agoston Jerga, Farhad Moshiri
  • Patent number: 11396661
    Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: July 26, 2022
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Thomas Cerruti, Stanislaw Flasinski, Xiaoran Fu, Arlene R. Howe, Sara Ann Salvador
  • Patent number: 11312975
    Abstract: The present invention relates to control of pest infestation by inhibiting one or more biological functions. The invention provides methods and compositions for such control, By feeding one or more recombinant double stranded RNA molecules provided by the invention to the pest, a reduction in pest infestation is obtained through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: April 26, 2022
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Claire A. CaJacob, Pascale Feldman, Gregory R. Heck, Irene Maria Antonia Nooren, Geert Plaetinck, Wendy T. Maddelein, Ty T. Vaughn
  • Patent number: 11286284
    Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: March 29, 2022
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Thomas A. Cerruti, Crystal L. Dart, Leigh H. English, Stanislaw Flasinski, Xiaoran Fu, Victor M. Guzov, Arlene R. Howe, Jay P. Morgenstern, James K. Roberts, Sara Salvador, Jinling Hung Wang
  • Publication number: 20220081695
    Abstract: Disclosed herein are methods of controlling insect pests which infest crop plants, in particular Spodoptera frugiperda (fall armyworm), Lygus hesperus (western tarnished plant bug), Euschistus heros (neotropical brown stink bug), and Plutella xylostella (diamondback moth), and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and plants with improved resistance to infestation by these insects. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of these insect pests.
    Type: Application
    Filed: August 13, 2021
    Publication date: March 17, 2022
    Applicant: Monsanto Technology LLC
    Inventors: James A. Baum, Brian D. Eads, Jeremy A. Kroemer, Christina Marie Taylor
  • Patent number: 11267849
    Abstract: Nucleotide sequences are disclosed that encode novel chimeric insecticidal proteins exhibiting Lepidopteran inhibitory activity. Particular embodiments provide compositions and transformed plants, plant parts, and seeds containing the recombinant nucleic acid molecules encoding one or more of the chimeric insecticidal proteins.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: March 8, 2022
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: James A. Baum, Thomas A. Cerruti, Crystal L. Dart, Leigh H. English, Stanislaw Flasinski, Xiaoran Fu, Victor M. Guzov, Arlene R. Howe, Jay P. Morgenstern, James K. Roberts, Sara A. Salvador, Jinling Wang
  • Patent number: 11186837
    Abstract: The present invention provides methods for controlling invertebrate pest infestations, for instance in plants, and related compositions and polynucleotides useful in such methods. More specifically, the present invention provides polynucleotides and methods of use thereof for modifying the expression of genes in an invertebrate pest, for instance through RNA interference.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: November 30, 2021
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Lex Evan Flagel, Gerrit Cornelis Segers, James K. Roberts
  • Patent number: 11091770
    Abstract: Disclosed herein are methods of controlling insect pests which infest crop plants, in particular Spodoptera frugiperda (fall armyworm), Lygus hesperus (western tarnished plant bug), Euschistus heros (neotropical brown stink bug), and Plutella xylostella (diamondback moth), and methods of providing plants resistant to such pests. Also disclosed are polynucleotides and recombinant DNA molecules and constructs useful in such methods, insecticidal compositions such as topical sprays containing insecticidal double-stranded RNAs, and plants with improved resistance to infestation by these insects. Further disclosed are methods of selecting target genes for RNAi-mediated silencing and control of these insect pests.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: August 17, 2021
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: James A. Baum, Brian D. Eads, Jeremy A. Kroemer, Christina Marie Taylor
  • Publication number: 20210100249
    Abstract: The present invention discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Application
    Filed: December 18, 2020
    Publication date: April 8, 2021
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: James A. BAUM, Artem G. EVDOKIMOV, Farhad MOSHIRI, Timothy J. RYDEL, Eric J. STURMAN, Moritz von RECHENBERG, Halong VU, Andrew M. WOLLACOTT, Meiying ZHENG
  • Publication number: 20210087580
    Abstract: The present invention is directed to controlling pest infestation by inhibiting one or more biological functions in an invertebrate pest. The invention discloses methods and compositions for use in controlling pest infestation by feeding one or more different recombinant double stranded RNA molecules to the pest in order to achieve a reduction in pest infestation through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
    Type: Application
    Filed: August 7, 2020
    Publication date: March 25, 2021
    Inventors: James A. Baum, Larry A. Gilbertson, David K. Kovalic, Thomas J. LaRosa, Maolong Lu, Tichafa R.I. Munyikwa, James K. Roberts, Wei Wu, Bei Zhang
  • Patent number: 10897910
    Abstract: The present invention discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: January 26, 2021
    Assignee: Monsanto Technology LLC
    Inventors: James A. Baum, Artem G. Evdokimov, Farhad Moshiri, Timothy J. Rydel, Eric J. Sturman, Moritz von Rechenberg, Halong Vu, Andrew M. Wollacott, Meiying Zheng